Results 151 to 160 of about 56,007 (232)

Elevated cortisol concentration in preterm sheep fetuses impacts heart development

Experimental Physiology, EarlyView.
Abstract The prepartum rise in cortisol promotes cardiac development and maturation. Here, we investigated the impact of elevated circulating cortisol during mid‐late gestation on cardiac growth and metabolism in fetal sheep. Saline or cortisol (2–3 mg in 4.4 mL/24 h) was infused into the fetal jugular vein from 109 to 116 days gestation (dG, term ...
Reza Amanollahi, Stacey L. Holman, Melanie R. Bertossa, Ashley S. Meakin, Vicki L. Clifton, Kent L. Thornburg, I. Caroline McMillen, Michael D. Wiese, Mitchell C. Lock, Janna L. Morrison   +9 more
wiley   +1 more source

Unraveling the role of hypoxia-inducible factors in cutaneous melanoma: from mechanisms to therapeutic opportunities. [PDF]

Cell Commun Signal
Bellazzo A, Montico B, Guerrieri R, Colizzi F, Steffan A, Polesel J, Fratta E.   +6 more
europepmc   +1 more source

A future hope for the treatment of diabetic retinopathy, manipulating hypoxia-inducible factor-1 alpha pathway [PDF]

, 2009
Abu El-Asrar, Ahmed M.
core   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker, James Andrew, Mastitskaya Svetlana   +2 more
wiley   +1 more source

Limiting Premenstrual Endometrial Hypoxia Inducible Factor 2 Alpha May Fine-Tune Endometrial Function at Menstruation.

J Clin Endocrinol Metab
Martínez-Aguilar R, Rowley BM, Walker C, Critchley HOD, Carmeliet P, Maybin JA.   +5 more
europepmc   +1 more source

Elucidating the Interplay of Hypoxia-Inducible Factor and Circadian Clock Signaling in Obstructive Sleep Apnea Patients. [PDF]

Int J Mol Sci
Gabryelska A, Turkiewicz S, Gajewski A, Białasiewicz P, Strzelecki D, Ditmer M, Chałubiński M, Sochal M.   +7 more
europepmc   +1 more source

Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase-2 and EGF receptor signaling [PDF]

, 2003
ATTOUB, S, Bruyneel, Erik, EMAMI, S, GESPACH, C, Mareel, Marcus, MAY, FEB, NGUYEN, QD, RODRIGUES, S, THIM, L, Van Aken, Elisabeth, VAN BOCXLAER, S, WESTLEY, BR   +11 more
core   +1 more source

Dietary nitrate supplementation mitigates age‐related changes at the neuromuscular junction in mice

The Journal of Physiology, EarlyView.
Abstract figure legend Ageing is associated with a decline in muscle mass and strength, namely sarcopenia, significantly impacting the quality of life in older individuals. Different strategies are being explored to counteract these detrimental effects. In the present study, we investigated a non‐invasive nutritional approach: the impact of 2 months of
Maira Rossi, Lucrezia Zuccarelli, Lorenza Brocca, Cristiana Sazzi, Clarissa Gissi, Paola Rossi, Bruno Grassi, Simone Porcelli, Roberto Bottinelli, Maria Antonietta Pellegrino   +9 more
wiley   +1 more source

Salivary levels of suPAR, HIF-1α and TNF-α in different grades of stage III periodontitis. [PDF]

BMC Oral Health
Taşdemir İ, Özgören Ö, Yılmaz HE, Kartal E, Altunyaprak Ş, Sağlam M.   +5 more
europepmc   +1 more source

Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbations [PDF]

, 2016
et al,, Urano, Fumihiko
core   +1 more source