Results 151 to 160 of about 65,592 (181)

The role of bHLH-PAS transcription factors in endoplasmic reticulum stress. [PDF]

Front Mol Biosci
Krauze I, Krzystek-Korpacka M, Maciejewska K, Greb-Markiewicz B.   +3 more
europepmc   +1 more source

Identification and validation of hypoxia-associated genes positively correlated with <i>HIF1A</i> in pulmonary adenocarcinoma. [PDF]

Transl Cancer Res
Zhu H, Wang Y, Chen Z, Guo R, Wu X, Jiang Y, Shu Y, Huang H.   +7 more
europepmc   +1 more source

Iron, the Essential Micronutrient: A Comprehensive Review of Regulatory Pathways of Iron Metabolism. [PDF]

Nutrients
Horváth A, Tamási K, Pap R, Jánosa G, Pandur E.   +4 more
europepmc   +1 more source

Theranostic Nanoparticles in Prostate Cancer: Disrupting Hypoxia-Induced Glycolysis by Targeting Hypoxia-Inducible Factor-1 Alpha and Downstream Metabolites. [PDF]

Cancer Med
Uti DE, Omang WA, Alum EU, Bawa I, Ugwu OP, Idowu AO, Atangwho IJ, Egbung GE.   +7 more
europepmc   +1 more source

Effects of intermittent hypoxia on adipose-derived mesenchymal stem cells in protecting alveolar type II cells from injury. [PDF]

PLoS One
Lai R, Chen S, Cui J, Liu X, Li Y.
europepmc   +1 more source

Bibliometric analysis and core target identification of network pharmacology on neuroinflammation in central nervous system disorders: Trends, collaborations, and future directions. [PDF]

Neuroprotection
Zhang Y, Hou S, Li J, Wang W, Jia S, Wang X, Xia Y, Wang Y.   +7 more
europepmc   +1 more source

Impact of Hypoxia-Inducible Factor-1α Gene Polymorphisms on Renal Cell Carcinoma Susceptibility in a Chinese Han Population.

Lifestyle Genom
Liao X, Zhou H, Huang P.
europepmc   +1 more source

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Apatinib Inhibits Angiogenesis in Intrahepatic Cholangiocarcinoma by Regulating the Vascular Endothelial Growth Factor Receptor-2/Signal Transducer and Activator of Transcription Factor 3/Hypoxia Inducible Factor 1 Subunit Alpha Signaling Axis

Pharmacology, 2021
<b><i>Introduction:</i></b> Intrahepatic cholangiocarcinoma (ICC), which is difficult to diagnose and is usually fatal due to its late clinical presentation and a lack of effective treatment, has risen over the past decades but without much improvement in prognosis. <b><i>Objective:</i></b> The study aimed
Man-Ping, Huang, Shan-Zhi, Gu, Bin, Huang, Guo-Wen, Li, Zheng-Ping, Xiong, Tian, Tang, Sai-Nan, Zeng   +6 more
openaire   +2 more sources

Abstract 4853: Knockout of hypoxia inducible factor 1 subunit alpha (HIF1a) augments the antitumor activity of EGFR CAR-NK cells

Cancer Research
Abstract Chimeric antigen receptor T-cell (CAR-T) therapies have gained remarkable success with durable remissions in hematologic malignancies. However, the potential adverse effects, including cytokine release syndrome (CRS), graft-versus-host disease (GVHD), neurotoxicity, and off-tumor toxicity, and high production cost have limited ...
Fanxiang Gao, Tingting Liu, Qin Wang, Yanxue Gong, Chao Wang, Feng Zhou, Zhuoxiao Cao   +6 more
openaire   +1 more source

Nimodipine ameliorates cognitive dysfunction and neurological injury after subarachnoid hemorrhage in rats by upregulating microRNA-31-5p targeting hypoxia-inducible factor 1 subunit alpha inhibitor.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Subarachnoid hemorrhage (SAH) is a hemorrhagic stroke with high short-term mortality that can lead to cognitive and neurological impairment. Accurate and appropriate treatment strategies are urgently needed. Nimodipine (NDP) can not only improve blood circulation in SAH patients but also repair ischemic neuronal damage.
S, Lu, T T, Chen, J K, Zhang
openaire   +2 more sources