Results 251 to 260 of about 35,931 (278)
Understanding the Impact of Hypoxia on Pulmonary Artery Endothelial Cells in Chronic Thromboembolic Pulmonary Hypertension Patients. [PDF]
Int J Mol SciRoger Y +17 more
europepmc +1 more source
Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling. [PDF]
Mol Med RepLi SJ +7 more
europepmc +1 more source
Tumor Biology, 2017 Hypoxia-inducible factor 1 is believed to play a prominent role in the survival and developing progress of cancers. As a result, inhibiting α subunit of hypoxia-inducible factor 1 represents an attractive strategy against tumor.
Le Zhao, Huilian Hou
exaly +2 more sources
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Pharmacology, 2021
<b><i>Introduction:</i></b> Intrahepatic cholangiocarcinoma (ICC), which is difficult to diagnose and is usually fatal due to its late clinical presentation and a lack of effective treatment, has risen over the past decades but without much improvement in prognosis. <b><i>Objective:</i></b> The study aimed
Man-Ping, Huang +6 more
openaire +2 more sources
<b><i>Introduction:</i></b> Intrahepatic cholangiocarcinoma (ICC), which is difficult to diagnose and is usually fatal due to its late clinical presentation and a lack of effective treatment, has risen over the past decades but without much improvement in prognosis. <b><i>Objective:</i></b> The study aimed
Man-Ping, Huang +6 more
openaire +2 more sources
International Journal of Surgical Pathology
Objective This study aims to evaluate the diagnostic utility of hypoxia inducible factor 1 subunit alpha (HIF1A) and carbonic anhydrase 9 (CA9) expression in differentiating between the 3 main types of pancreatic cystic neoplasms (PCNs): serous cystic neoplasms (SCNs), mucinous cystic neoplasms (MCNs), and ...
Cuiping Li +5 more
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Objective This study aims to evaluate the diagnostic utility of hypoxia inducible factor 1 subunit alpha (HIF1A) and carbonic anhydrase 9 (CA9) expression in differentiating between the 3 main types of pancreatic cystic neoplasms (PCNs): serous cystic neoplasms (SCNs), mucinous cystic neoplasms (MCNs), and ...
Cuiping Li +5 more
openaire +1 more source
Cellular and molecular biology (Noisy-le-Grand, France), 2016
To determine the significance of miR—214 expression in ischemic post—conditioning. Sixty rats were grouped to establish animal models. Immuno— luminescence and chemical methods were used to detect oxidative stress indicators. Hemodynamics indexes were measured by carotid artery intubation, and ischemia and infarction areas by Evans ...
D-Y, Wan, Z, Zhang, H-H, Yang
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To determine the significance of miR—214 expression in ischemic post—conditioning. Sixty rats were grouped to establish animal models. Immuno— luminescence and chemical methods were used to detect oxidative stress indicators. Hemodynamics indexes were measured by carotid artery intubation, and ischemia and infarction areas by Evans ...
D-Y, Wan, Z, Zhang, H-H, Yang
openaire +1 more source
Cancer Research
Abstract Chimeric antigen receptor T-cell (CAR-T) therapies have gained remarkable success with durable remissions in hematologic malignancies. However, the potential adverse effects, including cytokine release syndrome (CRS), graft-versus-host disease (GVHD), neurotoxicity, and off-tumor toxicity, and high production cost have limited ...
Fanxiang Gao +6 more
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Abstract Chimeric antigen receptor T-cell (CAR-T) therapies have gained remarkable success with durable remissions in hematologic malignancies. However, the potential adverse effects, including cytokine release syndrome (CRS), graft-versus-host disease (GVHD), neurotoxicity, and off-tumor toxicity, and high production cost have limited ...
Fanxiang Gao +6 more
openaire +1 more source
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Subarachnoid hemorrhage (SAH) is a hemorrhagic stroke with high short-term mortality that can lead to cognitive and neurological impairment. Accurate and appropriate treatment strategies are urgently needed. Nimodipine (NDP) can not only improve blood circulation in SAH patients but also repair ischemic neuronal damage.
S, Lu, T T, Chen, J K, Zhang
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Subarachnoid hemorrhage (SAH) is a hemorrhagic stroke with high short-term mortality that can lead to cognitive and neurological impairment. Accurate and appropriate treatment strategies are urgently needed. Nimodipine (NDP) can not only improve blood circulation in SAH patients but also repair ischemic neuronal damage.
S, Lu, T T, Chen, J K, Zhang
openaire +2 more sources
Variation of Hypoxia Inducible Factor 1 alpha subunit (HIF-1α) and Prolyl Hydroxylase Domain 2 (PHD2) transcripts in Toxoplasma gondii infection: a preliminary comparative analysis. [PDF]
, 2017 Toxoplasma gondii infects nearly one-third of the world population [1]. Virtually all species can be infected, but the parasite spreads more easily among some species (e.g. Pig) that infect humans more often than others (e.g. Horse). Investigating which host pathways are modulated by T.
Annamaria Castello +4 more
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