HER2 (neu) Signaling Increases the Rate of Hypoxia-Inducible Factor 1α (HIF-1α) Synthesis: Novel Mechanism for HIF-1-Mediated Vascular Endothelial Growth Factor Expression [PDF]
Erik Laughner+4 more
openalex +1 more source
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
G. Semenza
semanticscholar +1 more source
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen+7 more
wiley +1 more source
Glyceryl trinitrate inhibits hypoxia-induced release of soluble fms-like tyrosine kinase-1 and endoglin from placental tissues [PDF]
Preeclampsia is associated with increased circulating levels of proinflammatory molecules, such as soluble fms-like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sEng).
Barsoum, Ivraym B.+2 more
core +1 more source
Involvement of Hypoxia-Inducible Factor 1 in Human Cancer.
Hypoxia-inducible factor 1 (HIF-1) mediates transcriptional responses to hypoxia. HIF-1 is composed of an O2- and growth factor-regulated HIF-1alpha subunit and a constitutively-expressed HIF-1beta subunit. Four lines of evidence indicate that HIF-1 contributes to tumor progression.
openaire +4 more sources
State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis+6 more
wiley +1 more source
Hypoxia-Inducible Factor 1-Mediated Inhibition of Peroxisome Proliferator-Activated Receptor α Expression During Hypoxia [PDF]
Sailaja Narravula, Sean P. Colgan
openalex +1 more source
Engineering Magnetotactic Bacteria as Medical Microrobots
Magnetotactic bacteria (MTB) are living microorganisms that produce magnetosomes for navigation using the Earth's geomagnetic field. Their built‐in magnetic components, along with their intrinsic and/or modified biological functions, make them one of the most promising platforms for making future living and programmable microrobots.
Jiaqi Wang+9 more
wiley +1 more source
Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasis
Gregg L. Semenza
openalex +1 more source
Cobalt Induces Heme Oxygenase-1 Expression by a Hypoxia-inducible Factor-independent Mechanism in Chinese Hamster Ovary Cells [PDF]
Pengfei Gong+7 more
openalex +1 more source