Results 251 to 260 of about 678,452 (368)

Mammalian oxygen sensing and hypoxia inducible factor-1

The International Journal of Biochemistry & Cell Biology, 1997
Wood, S, Ratcliffe, P
openaire   +2 more sources

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Iron Chelators in the Management of Autoimmune-Induced Alopecia: A Focus on Hypoxia-Inducible Factor 1 Modulation and Hair Restoration. [PDF]

J Clin Med
Pagani A, Thor D, Panayi AC, Klein SM, Geis S, Knoedler L, Knoedler S, Perozzo FAG, Sofo G, Loucas R, Prantl L, Duscher D.   +11 more
europepmc   +1 more source

Cholesterol Exacerbates the Pathophysiology of Non-Alcoholic Steatohepatitis by Upregulating Hypoxia-Inducible Factor 1 and Modulating Microcirculatory Dysfunction. [PDF]

Nutrients, 2023
Pereira ENGDS, Araujo BP, Rodrigues KL, Silvares RR, Guimarães FV, Martins CSM, Flores EEI, Silva PMRE, Daliry A.   +8 more
europepmc   +1 more source

Akt and Hypoxia-Inducible Factor-1 Independently Enhance Tumor Growth and Angiogenesis [PDF]

, 2004
Andrew M. Arsham, David R. Plas, Craig B. Thompson, M. Celeste Simon   +3 more
openalex   +1 more source

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Advanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu, Min Chen, Chen‐Yu Jiang, Dai‐Ji Jiang, Xu Zhang, Xiao‐He Xu, Yi‐Wei Liu, Bei Feng, Lin‐Cai Ye, Yang‐Yang He, Xu Huang, Yi‐Chi Zhang, Xing‐Liang Zhou, Yi Shen, Tian‐Yu Liu, Li‐Jun Fu, Yi Yan, Hao Zhang   +17 more
wiley   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia-Inducible Factor-1 Signaling Pathway. [PDF]

Adv Sci (Weinh)
Zhao LN, Wang RL, Liu RX, Zheng MR, Zhao L, Li BF, Li JL, Liu DS, He XX, Peng QB, Li K, Lin TX, Liu YY, He SP, Lu J, Zheng SY, Liu X, Huang FZ.   +17 more
europepmc   +1 more source

Tale of two transcription factors: NF-кB and HIF crosstalk [PDF]

, 2013
Bandarra, D., Rocha, S.
core   +1 more source

Transcriptional Up-regulation of Inhibitory PAS Domain Protein Gene Expression by Hypoxia-inducible Factor 1 (HIF-1) [PDF]

, 2007
Yuichi Makino, Rie Uenishi, Kensaku Okamoto, Tsubasa Isoe, Osamu Hosono, Hirotoshi Tanaka, Arvydas Kanopka, Lorenz Poellinger, Masakazu Haneda, Chikao Morimoto   +9 more
openalex   +1 more source

Targeting Hypoxia‐Inducible Factor‐1&agr;/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin‐induced Pulmonary Fibrosis

American Journal of Respiratory Cell and Molecular Biology, 2017
Justin Goodwin, Hyunsung Choi, Meng-Hsiung Hsieh, Michael L. Neugent, Jung-Mo Ahn, Heather N. Hayenga, P. Singh, D. Shackelford, In-kyu Lee, V. Shulaev, S. Dhar, Norihiko Takeda, Jung-whan Kim   +12 more
semanticscholar   +1 more source