Neuroprotective Mechanisms of Hyperbaric Oxygen Therapy in Cerebral Ischemia-Hypoxia Injury Following Cardiopulmonary Resuscitation. [PDF]
Huang Y, Liu X, Yang X, Zhang S.
europepmc +1 more source
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Integrated Gut-Brain Axis Response to Freezing and Recovery in Freeze-Tolerant Fish, <i>Perccottus glenii</i>. [PDF]
Huang Y +7 more
europepmc +1 more source
TMEM16A channel signalling microdomains in the regulation of vascular function
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley +1 more source
The interplay between neuroinflammation and endothelial dysfunction in cerebral small vessel disease. [PDF]
Jin C, Zhao Y.
europepmc +1 more source
14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley +1 more source
The nitrate-nitrite-nitric oxide pathway of neuroinflammation and cognitive impairment in ischemic stroke. [PDF]
Liu J +9 more
europepmc +1 more source
Neuromuscular fatigability with repeated exercise in hypoxia: From single‐joint paradigms to sprints
Abstract figure legend Acute hypobaric or normobaric hypoxic exposure accelerates neuromuscular fatigability during repeated exercise. Indices of peripheral and central fatigue are not different at exhaustion in mild, moderate and severe hypoxia compared with normoxia, but task failure occurs earlier.
Luca Ruggiero +5 more
wiley +1 more source
Noble gases xenon and argon: from cellular signalling mechanisms to organoprotection and clinical applications. [PDF]
Chen Q +7 more
europepmc +1 more source
Mechanisms of haemoglobin mass expansion following heat stress
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins +4 more
wiley +1 more source

