Results 251 to 260 of about 123,355 (307)

Neuroprotective Effect of Clemastine Improved Oligodendrocyte Proliferation through the MAPK/ERK Pathway in a Neonatal Hypoxia Ischemia Rat Model. [PDF]

Int J Mol Sci
Bernis ME, Hakvoort C, Nacarkucuk E, Burkard H, Bremer AS, Zweyer M, Maes E, Grzelak KA, Sabir H.   +8 more
europepmc   +1 more source

The Temporal Relationship between Blood-Brain Barrier Integrity and Microglial Response following Neonatal Hypoxia Ischemia. [PDF]

Cells
Jithoo A, Penny TR, Pham Y, Sutherland AE, Smith MJ, Petraki M, Fahey MC, Jenkin G, Malhotra A, Miller SL, McDonald CA.   +10 more
europepmc   +1 more source

Neonatal hypoxia-ischemia alters the events governing the hippocampal critical period of postnatal synaptic plasticity leading to deficits in working memory in mice. [PDF]

Neurobiol Dis
Parmar P, Spahic H, Lechner C, St Pierre M, Carlin K, Nugent M, Chavez-Valdez R.   +6 more
europepmc   +1 more source

Prevalence of hearing impairment in neonatal encephalopathy due to hypoxia-ischemia: a systematic review and meta-analysis. [PDF]

Pediatr Res
Pawale D, Fursule A, Tan J, Wagh D, Patole S, Rao S.   +5 more
europepmc   +1 more source

URB447 Is Neuroprotective in Both Male and Female Rats after Neonatal Hypoxia-Ischemia and Enhances Neurogenesis in Females. [PDF]

Int J Mol Sci
Beldarrain G, Chillida M, Hilario E, Herrero de la Parte B, Álvarez A, Alonso-Alconada D.   +5 more
europepmc   +1 more source

Intestinal microbiota modulates neuroinflammatory response and brain injury after neonatal hypoxia-ischemia. [PDF]

Gut Microbes
Drobyshevsky A, Synowiec S, Goussakov I, Fabres R, Lu J, Caplan M.   +5 more
europepmc   +1 more source

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New concepts in perinatal hypoxia ischemia encephalopathy

Current Neurology and Neuroscience Reports, 2008
This article summarizes recent insights into perinatal hypoxic-ischemic brain injury in the neonate. Before effective treatments can be offered, diagnosis, timing, and an understanding of the pathogenesis are imperative. The analysis of appropriate animal models is also summarized in this review.
Joseph, Scafidi, Vittorio, Gallo
openaire   +2 more sources

Brief Hypoxia-Ischemia Initially Damages Cerebral Neurons

Archives of Neurology, 1975
Rats were studied during cerebral hypoxic ischemia to determine whether neurons or blood vessels suffered the first damage. Ten or more minutes of unilateral carotid artery occlusion combined with systemic hypoxemia (PaO-2, 21 mm Hg) produced neuronal but not vascular damage in the ipsilateral cerebral hemispheres of 18 of 29 rats (62%); two and five ...
D E, Levy, J B, Brierley, D G, Silverman, F, Plum   +3 more
openaire   +2 more sources

Autophagy in hypoxia-ischemia induced brain injury

The Journal of Maternal-Fetal & Neonatal Medicine, 2012
Autophagy is an endogenous tightly regulated process responsible for the degradation of damaged and dysfunctional cellular organelles and protein aggregates. Emerging data indicate a strong and complex interaction among autophagy, apoptosis and necrosis. We studied these interactions in a neonatal model of hypoxia-ischemia (HI).
BALDUINI, WALTER, CARLONI, SILVIA, G. Buonocore   +2 more
openaire   +5 more sources

ORP150 protects against hypoxia/ischemia-induced neuronal death

Nature Medicine, 2001
Oxygen-regulated protein 150 kD (ORP150) is a novel endoplasmic-reticulum-associated chaperone induced by hypoxia/ischemia. Although ORP150 was sparingly upregulated in neurons from human brain undergoing ischemic stress, there was robust induction in astrocytes.
Osamu Hori, Masaru Okabe
exaly   +3 more sources