Results 241 to 250 of about 409,719 (296)

Dysregulation of Brain Cholesterol Biosynthetic Pathway following Hypoxia Ischemia in Neonatal Mice.

Dev Neurosci
Lu F, Yen C, Corley CD, McDonald JG, Manninen T, Stewart NR, Zhu CM, Ferriero DM, Jiang X.   +8 more
europepmc   +1 more source

Enhancing 7-dehydrocholesterol suppresses brain ferroptosis and tissue injury after neonatal hypoxia-ischemia. [PDF]

Sci Rep
Genaro-Mattos TC, Korade Z, Sahar NE, Angeli JPF, Mirnics K, Peeples ES.   +5 more
europepmc   +1 more source

Acute seizure activity in neonatal inflammation-sensitized hypoxia-ischemia in mice. [PDF]

PLoS One
June A, Matysik W, Marlicz M, Zucker E, Wagley PK, Kuan CY, Burnsed J.   +6 more
europepmc   +1 more source

Deep Learning for Generalized EEG Seizure Detection after Hypoxia-Ischemia-Preclinical Validation. [PDF]

Bioengineering (Basel)
Abbasi H, Davidson JO, Dhillon SK, Zhou KQ, Wassink G, Gunn AJ, Bennet L.   +6 more
europepmc   +1 more source

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Transgenerational effects of neonatal hypoxia‐ischemia in progeny

International Journal of Developmental Neuroscience, 2013
AbstractNeonatal hypoxia‐ischemia (HI) affects 60% of low birth weight infants and up to 40% of preterm births. Cell death and brain injury after HI have been shown to cause long‐lasting behavioral deficits. By using a battery of behavioral tests on second generation 3‐week‐old rodents, we found that neonatal HI is associated with behavioral outcomes ...
Smitha K, Infante, Harriett C, Rea, J R, Perez-Polo   +2 more
openaire   +2 more sources

Regional Changes in Metabolism in Hypoxia-Ischemia

1977
The purpose of this study is to describe regional metabolic changes following an episode of cerebral ischemia in the cat. Regional characterization of metabolic derangements is imperative because it is unlikely that cerebral blood flow is uniformly reduced in most hypoxic-ischemic episodes.1, 2, 3 Furthermore, neurons in discrete anatomic regions such ...
F A, Welsh, M J, O'Connor, W, Rieder, V R, Marcy   +3 more
openaire   +2 more sources

New concepts in perinatal hypoxia ischemia encephalopathy

Current Neurology and Neuroscience Reports, 2008
This article summarizes recent insights into perinatal hypoxic-ischemic brain injury in the neonate. Before effective treatments can be offered, diagnosis, timing, and an understanding of the pathogenesis are imperative. The analysis of appropriate animal models is also summarized in this review.
Joseph, Scafidi, Vittorio, Gallo
openaire   +2 more sources

Impairment of perinatal hypoxia–ischemia to the preterm brainstem

Journal of the Neurological Sciences, 2009
Hypoxia-ischemia is a major perinatal problem that results in severe damage to the newborn brain. This study assessed functional integrity of the brainstem at term in preterm infants after perinatal hypoxia-ischemia to shed light on the influence of hypoxia-ischemia on the preterm brainstem.
Ze D, Jiang, Dorothea M, Brosi, C, Chen, Andrew R, Wilkinson   +3 more
openaire   +2 more sources

Pre- and Perinatal Ischemia-Hypoxia, the Ischemia-Hypoxia Response Pathway, and ADHD Risk [PDF]

Behavior Genetics, 2016
This review focuses on how measured pre- and perinatal environmental and (epi)genetic risk factors are interrelated and potentially influence one, of many, common developmental pathway towards ADHD. Consistent with the Developmental Origins of Health and
Jessica Kaczorowski, Taylor Smith, Valerie Knopik   +2 more
exaly   +1 more source

Autophagy in hypoxia-ischemia induced brain injury

The Journal of Maternal-Fetal & Neonatal Medicine, 2012
Autophagy is an endogenous tightly regulated process responsible for the degradation of damaged and dysfunctional cellular organelles and protein aggregates. Emerging data indicate a strong and complex interaction among autophagy, apoptosis and necrosis. We studied these interactions in a neonatal model of hypoxia-ischemia (HI).
BALDUINI, WALTER, CARLONI, SILVIA, G. Buonocore   +2 more
openaire   +5 more sources