Respiratory sympathetic modulation is augmented in chronic kidney disease [PDF]
Respiratory Physiology and Neurobiology, Elsevier, In press, 2019 Respiratory modulation of sympathetic nerve activity (respSNA) was studied in a hypertensive rodent model of chronic kidney disease (CKD) using Lewis Polycystic Kidney (LPK) rats and Lewis controls. In adult animals under in vivo anaesthetised conditions (n=8-10/strain), respiratory modulation of splanchnic and renal nerve activity was compared under ...
arxiv
Predicting Hypoxia in Brain Tumors from Multiparametric MRI [PDF]
arXivThis research paper presents a novel approach to the prediction of hypoxia in brain tumors, using multi-parametric Magnetic Resonance Imaging (MRI). Hypoxia, a condition characterized by low oxygen levels, is a common feature of malignant brain tumors associated with poor prognosis.
arxiv
Multi-scale modeling of Snail-mediated response to hypoxia in tumor progression [PDF]
arXivTumor cell migration within the microenvironment is a crucial aspect for cancer progression and, in this context, hypoxia has a significant role. An inadequate oxygen supply acts as an environmental stressor inducing migratory bias and phenotypic changes.
arxiv
A phenotype-structured mathematical model for the influence of hypoxia on oncolytic virotherapy [PDF]
arXivThe effectiveness of oncolytic virotherapy is significantly affected by several elements of the tumour microenvironment, which reduce the ability of the virus to infect cancer cells. In this work, we focus on the influence of hypoxia on this therapy and develop a novel continuous mathematical model that considers both the spatial and epigenetic ...
arxiv
Oxygen, Angiogenesis, Cancer and Immune Interplay in Breast Tumor Micro-Environment: A Computational Investigation [PDF]
arXivBreast cancer is one of the most challenging global health problems among women. This study investigates the intricate breast tumor microenvironment (TME) dynamics utilizing data from Mammary-specific Polyomavirus Middle T Antigen Overexpression mouse models (MMTV-PyMT).
arxiv
Utility of the Respiratory Compensation Point for Estimating Critical Power: Insights From Normoxia and Hypoxia. [PDF]
Eur J Sport SciMarwood S +4 more
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Differential influence of 1,8-Cineol on distinct hypoxia-related immune alterations in human monocytes. [PDF]
Sci RepJagodzinski N +6 more
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Progressive Deactivation of Hydroxylases Controls Hypoxia-Inducible Factor-1α-Coordinated Cellular Adaptation to Graded Hypoxia. [PDF]
Research (Wash D C)Wang P, Zhang XP, Liu F, Wang W.
europepmc +1 more source
Manganese Uptake and Lethality in the Sea Star Asterias rubens: Effect of Hypoxia. [PDF]
Bull Environ Contam ToxicolBjerregaard P, Hansen SN.
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How reducing oxygen-transport may lower the risk of developing Parkinson's disease. [PDF]
NPJ Parkinsons DisBurtscher J +5 more
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