Results 281 to 290 of about 240,846 (306)

Zinc-dependent suppression of TNF-alpha production is mediated by protein kinase A-induced inhibition of Raf-1, I kappa B kinase beta, and NF-kappa B.

Journal of immunology (Baltimore, Md. : 1950), 2007
Excessive and permanent cytokine production in response to bacterial LPS causes cell and tissue damage, and hence organ failure during sepsis. We have previously demonstrated that zinc treatment prevents LPS-induced TNF-alpha expression and production in human monocytes by inhibiting cyclic nucleotide phosphodiesterase (PDE) activity and expression ...
Verena, von Bülow, Svenja, Dubben, Gabriela, Engelhardt, Silke, Hebel, Birgit, Plümäkers, Holger, Heine, Lothar, Rink, Hajo, Haase   +7 more
openaire   +1 more source

The activity of a 70 kilodalton I kappa B molecule identical to the carboxyl terminus of the p105 NF-kappa B precursor is modulated by protein kinase A.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1993
The p50 subunit of NF-kappa B is derived from the amino terminus of a 105 kilodalton precursor. The p105 carboxyl terminus, which contains ankyrin-like repeats, a feature of I kappa B molecules, regulates the cytoplasmic retention of p105 and inhibits DNA binding by the precursor.
S, Gerondakis, N, Morrice, I B, Richardson, R, Wettenhall, J, Fecondo, R J, Grumont   +5 more
openaire   +1 more source

Overexpression of RelB in transgenic mice does not affect I kappa B alpha levels: differential regulation of RelA and RelB by the inhibitor protein.

Oncogene, 1996
In mouse lymphoid tissues, RelB heterodimers represent the constitutive kappa B-binding activity, whereas RelA and c-Rel complexes most likely are involved in inducible kappa B-binding and gene activation. Our laboratory has previously shown that the potential excess of NF-kappa B activity in transgenic mice overexpressing RelA is counteracted by a ...
F, Weih, S A, Lira, R, Bravo
openaire   +1 more source

Activation of the NF-kappa B and I kappa B system in smooth muscle cells after rat arterial injury. Induction of vascular cell adhesion molecule-1 and monocyte chemoattractant protein-1.

The American journal of pathology, 1997
The NF-kappa B transcription factor family and its inhibitory proteins (I kappa B) form an autoregulatory system that has been linked to endothelial gene expression and vascular disease. To determine the role of the NF-kappa B/I kappa B system in smooth muscle cells (SMCs) in vivo, the present study used the balloon catheter injury model in the rat ...
D B, Landry, L L, Couper, S R, Bryant, V, Lindner   +3 more
openaire   +1 more source

Higher-order band topology

Nature Reviews Physics, 2021
Bi-Ye Xie, Hai-Xiao Wang, Xiujuan Zhang
exaly  

TNF-alpha-induced cyclooxygenase-2 expression in human lung epithelial cells: involvement of the phospholipase C-gamma 2, protein kinase C-alpha, tyrosine kinase, NF-kappa B-inducing kinase, and I-kappa B kinase 1/2 pathway.

Journal of immunology (Baltimore, Md. : 1950), 2000
TNF-alpha induced a dose- and time-dependent increase in cyclooxygenase-2 (COX-2) expression and PGE2 formation in human NCI-H292 epithelial cells. Immunofluorescence staining demonstrated that COX-2 was expressed in cytosol and nuclear envelope. Tyrosine kinase inhibitors (genistein or herbimycin) or phosphoinositide-specific phospholipase C inhibitor
C C, Chen, Y T, Sun, J J, Chen, K T, Chiu   +3 more
openaire   +1 more source

Broadband convolutional processing using band-alignment-tunable heterostructures

Nature Electronics, 2022
Pengfei Wang, Shi-Jun Liang, Xing Zhou
exaly  

Pseudospin-selective Floquet band engineering in black phosphorus

Nature, 2023
Shaohua Zhou, Changhua Bao
exaly  

Catalogue of flat-band stoichiometric materials

Nature, 2022
Nicolas Regnault, Yuanfeng Xu, Ming-Rui Li   +2 more
exaly  

Band structure engineering and defect control of Ta3N5 for efficient photoelectrochemical water oxidation

Nature Catalysis, 2020
Yequan Xiao, Chao Feng, Faze Wang
exaly