Results 81 to 90 of about 240,846 (306)

Portulaca oleracea L. alleviates liver injury in streptozotocin-induced diabetic mice

Drug Design, Development and Therapy, 2017
Guoyin Zheng,1,* Fengfeng Mo,2,* Chen Ling,3,* Hao Peng,1 Wei Gu,1 Min Li,2 Zhe Chen1 1Department of Traditional Chinese Medicine, Changhai Hospital, 2Department of Military Hygiene, Second Military Medical University, 3Department of Biology, School of ...
Zheng G, Mo F, Ling C, Peng H, Gu W, Li M, Chen Z   +6 more
doaj  

Bioactive Constituents from the Roots of Eurycoma longifolia

Molecules, 2019
Four new phenolic components, eurylophenolosides A (1) and B (2), eurylolignanosides A (3) and B (4), along with twelve known compounds were isolated from the roots of Eurycoma longifolia Jack.
Jingya Ruan, Zheng Li, Ying Zhang, Yue Chen, Mengyang Liu, Lifeng Han, Yi Zhang, Tao Wang   +7 more
doaj   +1 more source

Trajectories of Physical Function in Canadian Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objectives We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham, Meghan McPherson, Lillian Lim, Roberta A. Berard, Matthew Berkowitz, Jean‐Philippe Proulx‐Gauthier, Brian M. Feldman, Nicole Johnson, Dax G. Rumsey, Heinrike Schmeling, Lori B. Tucker, Thomas Loughin, Kristin M. Houghton, Jaime Guzman, The CAPRI Registry Investigators   +14 more
wiley   +1 more source

Immunomodulatory effects of 17-O-acetylacuminolide in RAW264.7 cells and HUVECs: involvement of MAPK and NF-κB pathways

Drug Design, Development and Therapy, 2014
Mouna Achoui,1 Karen Heyninck,2 Chung Yeng Looi,1 Ali Mohd Mustafa,1 Guy Haegeman,2 Mohd Rais Mustafa1 1Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia; 2Department of Physiology, Laboratory of Eukaryotic ...
Achoui M, Heyninck K, Looi CY, Mustafa AM, Haegeman G, Mustafa MR   +5 more
doaj  

Identification of an I kappa B alpha-associated protein kinase in a human monocytic cell line and determination of its phosphorylation sites on I kappa B alpha.

The Journal of biological chemistry, 1996
Nuclear factor kappa B (NF-kappa B) is stored in the cytoplasm as an inactive form through interaction with I kappa B. Stimulation of cells leads to a rapid phosphorylation of I kappa B alpha, which is presumed to be important for the subsequent degradation.
K, Kuno, Y, Ishikawa, M K, Ernst, M, Ogata, N R, Rice, N, Mukaida, K, Matsushima   +6 more
openaire   +1 more source

A Novel Specific Role for IκB Kinase Complex-associated Protein in Cytosolic Stress Signaling [PDF]

Journal of Biological Chemistry, 2002
We demonstrate here a novel role for the I kappa B kinase complex-associated protein (IKAP) in the regulation of activation of the mammalian stress response via the c-Jun N-terminal kinase (JNK)-signaling pathway. We cloned IKAP as a JNK-associating protein using the Ras recruitment yeast two-hybrid system.
Holmberg, Christian Henrik, Katz, S., Lerdrup, M., Herdegen, T., Jaattela, M., Aronheim, A., Kallunki, T.   +6 more
openaire   +2 more sources

Developmental regulation of the heat shock response by nuclear transport factor karyopherin-α3 [PDF]

, 2001
During early stages of Drosophila development the heat-shock response cannot be induced. It is reasoned that the adverse effects on cell cycle and cell growth brought about by Hsp70 induction must outweigh the beneficial aspects of Hsp70 induction in the
Chen, Tianxin, Fang, Xiang-dong, Parker, Carl S., Tran, Kim   +3 more
core  

New insights into the classification and nomenclature of cortical GABAergic interneurons. [PDF]

, 2013
A systematic classification and accepted nomenclature of neuron types is much needed but is currently lacking. This article describes a possible taxonomical solution for classifying GABAergic interneurons of the cerebral cortex based on a novel, web ...
A Karagiannis, A von Kölliker, AK Jain, Alex Thomson, Alfonso Fairén, Andreas Burkhalter, Bernardo Rudy, Bruno Cauli, C Golgi, CC Sherwood, Chet C. Sherwood, Chris J. McBain, Concha Bielza, D Amaral, D Feldmeyer, D Hamilton, David A. Lewis, David Fitzpatrick, Dirk Feldmeyer, E Clarke, Edward G. Jones, EG Jones, G Meyer, GA Ascoli, GA Ascoli, Giorgio A. Ascoli, Gord Fishell, Gordon M. Shepherd, Guillermo González-Burgos, Gábor Tamás, Hannah Monyer, Hanno S. Meyer, Henry Markram, HS Meyer, J DeFelipe, J DeFelipe, J Pearl, J Welagen, Javier DeFelipe, Jean Rossier, JF Staiger, JH Jackson, Jochen F. Staiger, John L. R. Rubenstein, Josh Huang, JT Porter, Kathleen Rockland, KS Rockland, L Tricoire, M Marín-Padilla, Massimo Scanziani, Oscar Marín, P Rakic, P Rakic, Patrick R. Hof, Pedro L. López-Cruz, Pedro Larrañaga, PL López-Cruz, PR Hof, R Berlin, R Malach, R Tomioka, Rafael Yuste, RF Hevner, RO Duda, Ruth Benavides-Piccione, S Melzer, Sacha B. Nelson, SD Larson, Sean Hill, Shaul Hestrin, SR Cajal, Stewart Anderson, T Meynert, Tamás F. Freund, TG Chowdhury, VB Mountcastle, VC Raykar, Y Kubota, Yasuo Kawaguchi, Yoshiyuki Kubota, Yun Wang, Zoltán Kisvárday   +82 more
core   +3 more sources

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

The dorsal protein enhances the biosynthesis and stability of theDrosophilaIkB homologue cactus [PDF]

Nucleic Acids Research, 1995
The cactus and dorsal proteins are Drosophila homologues of mammalian I kappa B cytoplasmic anchor proteins and rel/NF kappa B transcription factors respectively. They are required for the generation of embryonic dorsoventral polarity and probably at later developmental stages for an innate immune response.
K, Kubota, N J, Gay
openaire   +2 more sources