Results 1 to 10 of about 1,151 (123)

Iatrogenic cerebral amyloid angiopathy and Alzheimer's disease co‐pathology [PDF]

Annals of Clinical and Translational Neurology
Iatrogenic cerebral amyloid angiopathy, a disease caused by contact with neurosurgical material or human growth hormone contaminated by beta‐amyloid peptide (Aβ), has a prion‐like transmission mechanism.
Francisco Hernández‐Fernández, Isabel Martínez‐Fernández, Rosa Barbella‐Aponte, Inmaculada Feria Vilar, Oscar Ayo‐Martín, Jorge García‐García, Rosa Collado, Alberto Andrés, Mar Hernández‐Guillamón, Francisco José Pena Pardo, Cristina Barrena, Miguel de laFuente, Gemma Serrano‐Heras, María Melero, Elena Lozano Setién, Luis López, Tomás Segura   +16 more
doaj   +5 more sources

Iatrogenic Cerebral Amyloid Angiopathy in Patients Treated With Cadaveric Dura Mater During Childhood Neurosurgery: A Retrospective Cohort Study [PDF]

European Journal of Neurology
Background: Iatrogenic cerebral amyloid angiopathy (iCAA) is a recently identified clinico-neuroradiological syndrome associated with medical procedures, particularly neurosurgical treatments involving cadaveric dura mater (e.g., Lyodura).
Slaven Pikija, Christoph J Griessenauer, Marieke J H Wermer   +2 more
exaly   +6 more sources

Case report of iatrogenic cerebral amyloid angiopathy after exposure to Lyodura: an Australian perspective [PDF]

Frontiers in Neuroscience, 2023
BackgroundRecently proposed diagnostic criteria for iatrogenic cerebral amyloid angiopathy (iCAA) have sparked increased recognition of cases across the globe.
Claire Muller, Claire Muller
doaj   +4 more sources

Cerebral Amyloid Angiopathy‐Related Inflammation in Iatrogenic Cerebral Amyloid Angiopathy [PDF]

European Journal of Neurology
ABSTRACT Introduction Cerebral amyloid angiopathy (CAA) related inflammation (CAA‐ri) is considered to be a distinct syndrome caused by an inflammatory response to amyloid‐β deposition in the walls of small leptomeningeal and cortical vessels in patients with sporadic CAA.
Larysa Panteleienko, Dermot Mallon, Gargi Banerjee   +2 more
exaly   +3 more sources

Ethical considerations of disclosure of iatrogenic cerebral amyloid angiopathy [PDF]

Alzheimer's and Dementia
Abstract Cerebral amyloid angiopathy (CAA) causes stroke and cognitive decline. The recently identified iatrogenic CAA subtype (iCAA) is thought to be transmitted through medical procedures involving cadaveric human material and potentially neurosurgical instruments or blood transfusions. This raises ethical questions concerning disclosure of iCAA.
Kanishk Kaushik, Nienke De Graeff, Gargi Banerjee   +2 more
exaly   +3 more sources

Iatrogenic cerebral amyloid angiopathy in older adults [PDF]

European Journal of Neurology
Background and purpose: An increasing number of cases of iatrogenic cerebral amyloid angiopathy (CAA) have now been reported worldwide. Proposed diagnostic criteria require a history of medical intervention with potential for amyloid-β transmission, for ...
Larysa Panteleienko, Dermot Mallon, Ahmed T Toosy   +2 more
exaly   +9 more sources

Iatrogenic cerebral amyloid angiopathy: Two case reports to explore clinical heterogeneity and pathological patterns [PDF]

Journal of Stroke and Cerebrovascular Diseases
Introduction: These case reports illustrate Iatrogenic Cerebral Amyloid Angiopathy (iCAA) due to neurosurgical procedures. Recent studies propose prion transmission during neurosurgery as a potential mechanism for β-amyloid seed implantation, linking ...
Carla Vera-Cáceres, MD, Nerses Nersesyan, MD, Maria Obon, MD, Ph.D, Mikel Terceño, MD, Ph.D, Joaquin Serena, MD, Ph.D, Juan Álvarez-Cienfuegos, MD, Tomàs Xuclà, MD, Saima Bashir, MD, Yolanda Silva, MD, Ph.D   +8 more
doaj   +5 more sources

Iatrogenic Cerebral Amyloid Angiopathy Post Neurosurgery: Frequency, Clinical Profile, Radiological Features, and Outcome [PDF]

Stroke, 2023
Background: Prion-like transmission of amyloid-ß through cadaveric dura, decades after neurosurgical procedures, has been hypothesized as an iatrogenic cause of cerebral amyloid angiopathy (CAA).
Kanishk Kaushik, Ellis S Van Etten, Bob Siegerink   +2 more
exaly   +5 more sources

Iatrogenic cerebral proteinopathies—The dawn of transmissible neurodegeneration? The example of cerebral amyloid angiopathy [PDF]

Frontiers in Neurology
Matija Zupan, Matija Zupan, Bruno Splavski, Bruno Splavski, Senta Frol, Senta Frol   +5 more
doaj   +5 more sources

The Inflammatory Side of Iatrogenic Cerebral Amyloid Angiopathy: Rethinking Therapeutic Opportunities [PDF]

Brain Sciences
Background: Iatrogenic cerebral amyloid angiopathy (iCAA) is a rare form of CAA occurring decades after neurosurgical procedures involving cadaveric dural grafts.
Mattia Losa, Andrea Donniaquio, Ilaria Gandoglia, Federico Massa, Fabio Gotta, Luca Sofia, Lorenzo Gualco, Enrico Peira, Andrea Chincarini, Luca Roccatagliata, Fabrizio Piazza, Massimo Del Sette, Matteo Pardini   +12 more
doaj   +2 more sources