Thanks to a more widespread knowledge of the disease, and improved diagnostic techniques, the clinical spectrum of cerebral amyloid angiopathy (CAA) is now broad.
Benedetta Storti +7 more
doaj +3 more sources
Cerebrospinal fluid biomarkers in cerebral amyloid angiopathy: insights from a clinical case series [PDF]
Cerebral amyloid angiopathy (CAA) is a small vessel disease characterized by the deposition of amyloid-beta in small cerebral vessels, which can lead to intracerebral hemorrhages and cognitive impairment.
Ana Silvia Sobreira Lima Verde +6 more
doaj +2 more sources
Iatrogenic cerebral amyloid angiopathy: two new cases and systematic review of case reports with neuropathological data [PDF]
Awareness concerning iatrogenic cerebral amyloid angiopathy (iCAA) is increasing but its pathophysiology remains unclear. We discuss the implications of the clinical, imaging and neuropathological findings in two previously unpublished cases of probable ...
Ana Sofia Costa +9 more
doaj +2 more sources
CSF and Plasma Biomarkers in Patients With Iatrogenic Cerebral Amyloid Angiopathy. [PDF]
Recently, a subset of patients affected by cerebral amyloid angiopathy (CAA) distinguished by atypical juvenile onset and a hypothesized iatrogenic origin (iatrogenic CAA, iCAA) has emerged. β-Amyloid (Aβ) accumulation evidenced by amyloid PET positivity or CSF Aβ decrease was included in the iCAA diagnostic criteria.
Pollaci G +20 more
europepmc +5 more sources
Iatrogenic cerebral amyloid angiopathy: An illustrative case of a newly introduced disease
AbstractBackground and purposeIatrogenic cerebral amyloid angiopathy (iCAA) is a specific type of cerebral amyloid angiopathy which is becoming increasingly diagnosed. It has been hypothesized that iCAA might arise as a late consequence of past neurosurgical interventions involving dural patch grafts.
Benedetta Storti, Anna Bersano
exaly +3 more sources
Iatrogenic cerebral amyloid angiopathy with inflammatory pathogenesis: A case report and literature review. [PDF]
Background: Iatrogenic cerebral amyloid angiopathy (iCAA) is a rare form of amyloid β (Aβ)-mediated small vessel disease associated with prior neurosurgical exposure, such as cadaveric dura mater grafting or other Aβ-contaminated materials.
Miyaoka R +3 more
europepmc +3 more sources
QUESTIONS UNDER STUDY: Alzheimer-type amyloid-β (Aβ) pathology was reported in brains of individuals developing iatrogenic Creutzfeldt-Jakob disease (iCJD) after treatment with human cadaveric growth hormone, and interpreted as evidence of human ...
Karl Frontzek +4 more
doaj +4 more sources
ABSTRACT NUMBER: ESOC2026A1784 LONG-TERM OUTCOME OF PATIENTS WITH IATROGENIC CEREBRAL AMYLOID ANGIOPATHY [PDF]
Abstract Background and aims Iatrogenic cerebral amyloid angiopathy (iCAA) has emerged as a rare but distinct CAA subtype, with increasing recognition worldwide. However, information on long-term prognosis remains limited. Methods
Simon Fandler-Höfler +9 more
europepmc +2 more sources
Medicolegal aspects of iatrogenic cerebral amyloid angiopathy. [PDF]
Jensen-Kondering U.
europepmc +2 more sources
Diagnosis, pathomechanisms and therapy of cerebral amyloid angiopathy-related inflammation (CAA-ri) [PDF]
Background Research of the past years has refined our perception of cerebral amyloid angiopathy-related inflammation (CAA-ri) as a subacute autoimmune encephalopathy, which is presumably caused by elevated CSF concentrations of anti-amyloid β (Aβ ...
Rebecca M. Seifert +2 more
doaj +2 more sources

