Results 11 to 20 of about 787 (101)

Cerebral Amyloid Angiopathy-Related Inflammation in Iatrogenic Cerebral Amyloid Angiopathy [PDF]

European Journal of Neurology
ABSTRACT Introduction Cerebral amyloid angiopathy (CAA) related inflammation (CAA‐ri) is considered to be a distinct syndrome caused by an inflammatory response to amyloid‐β deposition in the walls of small leptomeningeal and cortical vessels in patients with sporadic CAA.
Dermot Mallon, Larysa Panteleienko, Michael S. Zandi   +2 more
exaly   +5 more sources

Ethical considerations of disclosure of iatrogenic cerebral amyloid angiopathy [PDF]

Alzheimer's and Dementia
Abstract Cerebral amyloid angiopathy (CAA) causes stroke and cognitive decline. The recently identified iatrogenic CAA subtype (iCAA) is thought to be transmitted through medical procedures involving cadaveric human material and potentially neurosurgical instruments or blood transfusions. This raises ethical questions concerning disclosure of iCAA.
Nienke de Graeff, Marieke Wermer, Ellis S. van Etten   +2 more
exaly   +7 more sources

Iatrogenic Cerebral Amyloid Angiopathy in Patients Treated With Cadaveric Dura Mater During Childhood Neurosurgery: A Retrospective Cohort Study [PDF]

European Journal of Neurology
ABSTRACT Background Iatrogenic cerebral amyloid angiopathy (iCAA) is a recently identified clinico‐neuroradiological syndrome associated with medical procedures, particularly neurosurgical treatments involving cadaveric dura mater (e.g., Lyodura). iCAA can manifest as intracerebral hemorrhages, focal seizures, and cognitive impairment, with the risk ...
Pikija S, Toma A, Radlberger R, Griessenauer CJ, Hecker C, Trinka E, Ki PH, Kraus T, Weis S, Wermer MJH, van Etten ES, Kaushik K.   +11 more
exaly   +7 more sources

Seed to Bleed: Iatrogenic Cerebral Amyloid Angiopathy [PDF]

Stroke, 2023
Andreas Charidimou
exaly   +4 more sources

Iatrogenic Cerebral Amyloid Angiopathy Post Neurosurgery: Frequency, Clinical Profile, Radiological Features, and Outcome [PDF]

Stroke, 2023
Background: Prion-like transmission of amyloid-ß through cadaveric dura, decades after neurosurgical procedures, has been hypothesized as an iatrogenic cause of cerebral amyloid angiopathy (CAA). We investigated new and previously described patients to assess the clinical profile, radiological features, and ...
Jaap Kappelle, Marieke Wermer, Floris Schreuder   +2 more
exaly   +9 more sources

Iatrogenic cerebral amyloid angiopathy: Two case reports to explore clinical heterogeneity and pathological patterns

Journal of Stroke and Cerebrovascular Diseases
Introduction: These case reports illustrate Iatrogenic Cerebral Amyloid Angiopathy (iCAA) due to neurosurgical procedures. Recent studies propose prion transmission during neurosurgery as a potential mechanism for β-amyloid seed implantation, linking ...
Mikel Terceño, Joaquin Serena, Yolanda Silva   +2 more
exaly   +6 more sources

Iatrogenic cerebral amyloid angiopathy in older adults [PDF]

European Journal of Neurology
AbstractBackground and purposeAn increasing number of cases of iatrogenic cerebral amyloid angiopathy (CAA) have now been reported worldwide. Proposed diagnostic criteria require a history of medical intervention with potential for amyloid‐β transmission, for example those using cadaveric dura mater or requiring instrumentation of the brain or spinal ...
Dermot Mallon, Ahmed Toosy, Marieke Wermer   +2 more
exaly   +7 more sources

Iatrogenic cerebral proteinopathies—The dawn of transmissible neurodegeneration? The example of cerebral amyloid angiopathy [PDF]

Frontiers in Neurology
Matija Zupan, Matija Zupan, Bruno Splavski, Bruno Splavski, Senta Frol, Senta Frol   +5 more
doaj   +5 more sources

Inflammatory Episode in a Patient With Probable Iatrogenic Cerebral Amyloid Angiopathy: An ARIA Before the Storm? [PDF]

Eur J Neurol
ABSTRACT Introduction Amyloid related imaging abnormalities effusion/edema (ARIA‐E) is seen in patients treated with antiamyloid antibodies. It resembles cerebral amyloid angiopathy (CAA) related inflammation (CAA‐ri) caused by an inflammatory response to amyloid deposition in the walls of cortical and leptomeningeal vessels in patients with sporadic ...
Jensen-Kondering U, Kuhlenbäumer G, Margraf NG.   +2 more
europepmc   +4 more sources

Iatrogenic cerebral amyloid angiopathy: two new cases and systematic review of case reports with neuropathological data [PDF]

Neurological Research and Practice
Awareness concerning iatrogenic cerebral amyloid angiopathy (iCAA) is increasing but its pathophysiology remains unclear. We discuss the implications of the clinical, imaging and neuropathological findings in two previously unpublished cases of probable ...
Ana Sofia Costa, João Pinho, Arno Reich, Omid Nikoubashman, Kay Nolte, Joachim Weis, Christian Boy, Felix M. Mottaghy, Jörg B. Schulz, Kathrin Reetz   +9 more
doaj   +2 more sources