Results 31 to 40 of about 757 (98)

Iatrogenic cerebral amyloid angiopathy after red blood cell transfusion? [PDF]

open access: yesEur J Neurol
DiFrancesco JC   +6 more
europepmc   +3 more sources

Iatrogenic cerebral amyloid angiopathy: an emerging clinical phenomenon

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 2022
In the last 6 years, following the first pathological description of presumed amyloid-beta (Aβ) transmission in humans (in 2015) and subsequent experimental confirmation (in 2018), clinical cases of iatrogenic cerebral amyloid angiopathy (CAA)—attributed to the transmission of Aβ seeds—have been increasingly recognised and reported.
Gargi Banerjee   +15 more
openaire   +3 more sources

Spontaneous intracerebral haemorrhage associated with early-onset cerebral amyloid angiopathy and Alzheimer’s disease neuropathological changes five decades after cadaveric dura mater graft

open access: yesActa Neuropathologica Communications, 2023
Cerebral amyloid angiopathy (CAA) is a small vessel disease, causing spontaneous intracerebral hemorrhage (ICH) in the elderly. It is strongly associated with Alzheimer disease (AD), as most CAA patients show deposition of Aβ—i.e.
Riccardo Milani   +11 more
doaj   +1 more source

Exogenous Aβ seeds induce Aβ depositions in the blood vessels rather than the brain parenchyma, independently of Aβ strain-specific information

open access: yesActa Neuropathologica Communications, 2021
Little is known about the effects of parenchymal or vascular amyloid β peptide (Aβ) deposition in the brain. We hypothesized that Aβ strain-specific information defines whether Aβ deposits on the brain parenchyma or blood vessels.
Tsuyoshi Hamaguchi   +7 more
doaj   +1 more source

Transmission of amyloid-beta and tau pathologies is associated with cognitive impairments in a primate

open access: yesActa Neuropathologica Communications, 2021
Amyloid-β (Aβ) pathology transmission has been described in patients following iatrogenic exposure to compounds contaminated with Aβ proteins. It can induce cerebral Aβ angiopathy resulting in brain hemorrhages and devastating clinical impacts ...
Suzanne Lam   +11 more
doaj   +1 more source

Amyloid-β Seeds in Alzheimer's Disease: Research Challenges and Implications. [PDF]

open access: yesJ Neurochem
The amyloid cascade hypothesis places amyloid‐β (Aβ) at the center of Alzheimer's disease (AD) pathogenesis. Evidence suggests that AD progresses in two phases: an early phase driven by Aβ aggregation and a later phase that progresses at least partly independently of Aβ.
Beschorner N   +3 more
europepmc   +2 more sources

IATROGENIC AMYLOID ANGIOPATHY AS A NEW CLINICAL PHENOMENON

open access: yesБайкальский медицинский журнал
Background. A literature search of various databases revealed mixed and largely contradictory results regarding the etiology, pathogenesis, prevalence, and diagnostic criteria of cerebral amyloid angiopathies and iatrogenic amyloid angiopathies, which ...
Ivan A. Stepanov   +2 more
doaj   +1 more source

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