Results 71 to 80 of about 2,517,895 (186)

GABAergic neurons of anterior thalamic reticular nucleus regulate states of consciousness in propofol‐ and isoflurane‐mediated general anesthesia

CNS Neuroscience &Therapeutics, Volume 30, Issue 6, June 2024.
Optogenetic and chemogenetic activation of the GABAergic neurons in the anterior sector of the thalamic reticular nucleus (aTRN) promote the induction of propofol‐ and isoflurane‐mediated general anesthesia. Abstract Background The thalamus system plays critical roles in the regulation of reversible unconsciousness induced by general anesthetics ...
Rulan Yi, Shiyu Chen, Fuwang Zhong, Dan Luo, Ying You, Tian Yu, Haiying Wang, Liang Zhou, Yu Zhang   +8 more
wiley   +1 more source

Overexpression of EphB2 in the basolateral amygdala is crucial for inducing visceral pain sensitization in rats subjected to water avoidance stress

CNS Neuroscience &Therapeutics, Volume 30, Issue 2, February 2024.
Overexpression of EphB2 in the basolateral amygdala may enhance synaptic plasticity through upregulating NMDARs, which results in visceral hypersensitivity and anxiety‐like behaviors in rats with psychological stress. Abstract Aims Basolateral amygdala (BLA), as a center for stress responses and emotional regulation, is involved in visceral ...
Guang‐Bing Duan, Jun‐Wen Wang, Hui‐Hui Sun, Zhi‐Yu Dong, Yan Zhang, Zhen‐Xiang Wang, Ye Chen, Ying Chen, Ying Huang, Shu‐Chang Xu   +9 more
wiley   +1 more source

Simultaneous Determination of Multi-Class Mushroom Toxins in Mushroom and Biological Liquid Samples Using LC-MS/MS

Separations
A comprehensive analytical method based on liquid chromatography–tandem mass spectrometry (LC-MS/MS) was developed for the simultaneous detection of 12 mushroom toxins (ibotenic acid, muscimol, muscarine, β-amanitin, α-amanitin, desoxoviroidin, γ ...
Junjia Lu, Jing Zhang, Haijiao Li, Chengye Sun   +3 more
doaj   +1 more source

Ibotenic acid induced demyelination in the central nervous system: a consequence of a local inflammatory response.

, 1988
We examined the effects of injections of ibotenic acid into the medial septum (MS), dorsal lateral geniculate nucleus (dLGN), caudate-putamen (CP) or fornix-fimbria (FF) on fibres close to the injection site.
Coffey, PJ, Allen, Y, Rawlins, John, Sinden, J, Perry, VH   +4 more
core   +1 more source

Visually or auditorily induced seizures involve the activation of nonhippocampal brain areas and hippocampal removal does not alleviate seizures in a mouse model of temporal lobe epilepsy

Epilepsia, Volume 65, Issue 1, Page 218-237, January 2024.
Abstract Objective Several studies have attributed epileptic activities in temporal lobe epilepsy (TLE) to the hippocampus; however, the participation of nonhippocampal neuronal networks in the development of TLE is often neglected. Here, we sought to understand how these nonhippocampal networks are involved in the pathology that is associated with TLE
Stephen Temitayo Bello, Shenghui Xu, Xiao Li, Junming Ren, Peter Jendrichovsky, Feixu Jiang, Zhoujian Xiao, Xiaoxiao Wan, Xi Chen, Jufang He   +9 more
wiley   +1 more source

Effects of ibotenic acid lesions of the dorsal hippocampus on contextual fear conditioning in mice: comparison with mammillary body lesions

, 2004
The goals of the present study were to determine if ibotenic acid lesions of the dorsal hippocampus (dHPC) or of mammillary body (MB) of the hypothalamus would induce similar contextual conditioning deficit in a fear-conditioning paradigm, previously ...
Beracochea, Daniel, Pierard, Christophe, Aurélie, Celerier   +2 more
core   +1 more source

Modified sensory processing in the barrel cortex of the Rat model of Alzheimer’s disease

مجله دانشگاه علوم پزشکی گرگان, 2011
Background and Objective: Alzheimer’s disease is caractrized by brain degenerative alterations with subsequent learning and memory loss. Learning and memory is closely associated with brain colinergic system.
Goshadrou F (PhD)
doaj  

Hippocampus-dependent place learning enables spatial flexibility in mice

Frontiers in Behavioral Neuroscience, 2012
Spatial navigation is a fundamental capability necessary in everyday life to locate food, social partners and shelter. It results from two very different strategies: (i) place learning which enables for flexible way finding and (ii) response learning ...
Karl R. Kleinknecht, Benedikt T. Bedenk, Sebastian F. Kaltwasser, Barbara eGruenecker, Yi-Chun eYen, Michael eCzisch, Carsten T. Wotjak   +6 more
doaj   +1 more source

Enzyme-luminescence method: Tool for real-time monitoring of natural neurotoxins in vitro and l-glutamate release from primary cortical neurons

Biotechnology Reports, 2016
Novel enzyme-luminescence method is used for the rapid and sensitive in vitro detection of natural neurotoxins (e.g., shellfish and mushroom toxins) using model brain cells. Paralytic shellfish poisons gonyautoxins (e.g., GTX2,3 and GTX1,4) were detected
S.M. Zakir Hossain
doaj   +1 more source

The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid

, 2004
We have determined the pharmacological activity of N-hydroxypyrazole analogues (3a and 4a) of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid (AMAA), as well as substituted ...
Egebjerg, Jan, Begtrup, Mikael, Bräuner-Osborne, Hans, Calí, Patrizia, Greenwood, Jeremy R, Hansen, Kasper B, Nielsen, Birgitte, Clausen, Rasmus P   +7 more
core   +1 more source