Results 51 to 60 of about 2,517,895 (186)

Ibotenic Acid-Induced Hematological Disorders in Rat Model of Alzheimer's Disease

, 2010
The present study was conducted in order to investigate the effects of right-unilateral lesion of substantia nigra neurons by means of Ibotenic acid, a cholinergic-selective neurotoxin, on hematological parameters in rats.
Keikhaei, B., RAHIM, FAKHER, Doulah, A. H., Sarkaki, A.   +3 more
core   +1 more source

Wherefore the Magic? The Evolutionary Role of Psilocybin in Nature

Ecology and Evolution, Volume 16, Issue 4, April 2026.
This study explores the evolutionary role of psilocybin, the psychedelic compound found in Psilocybe mushrooms. We provide the first experimental tests of defence and community‐level evidence for invertebrate responses to psilocybin‐producing fungi, revealing significant negative effects on invertebrate locomotion, development, and survival.
K. J. Matthews Nicholass, I. Flis, M. E. Hanley, M. E. Knight, S. M. Lane, G. Littlejohn, M. D. F. Thom, R. A. Billington, R. Boden, R. Cummins, B. J. Green, C. Griffin, S. Jones, D. Salmon, I. Sleep, N. Smirnoff, J. S. Ellis   +16 more
wiley   +1 more source

Synthetic Strategies to Access Fluorinated Azoles

European Journal of Organic Chemistry, Volume 28, Issue 47, December 15, 2025.
This review highlights recent synthetic strategies for introducing fluorine groups (mono‐, di‐, and trifluoromethylation) into 11 major azole classes, identifying research gaps to inform future innovations in materials science, medicinal chemistry, and biomedical research.
Mohammed K. Abd El‐Gaber, Mario Djugovski, Tzu‐Yu Huang, Sweta Adhikari, Sudeshna Roy   +4 more
wiley   +1 more source

Ibotenic acid lesion of the DG impairs RM and WM but improves the processing of interference.

, 2015
(A-C) Percentage of correct choices ± s.e.m per Block of days in RM (A), LIWM (B) and in HIWM (C) for ibotenic acid lesioned and control animals. † Group effect; * Block effect; * p < 0.05; ** p < 0.01; # interaction p < 0.05.
Paul-Antoine Libourel (561599), Emilie Sapin (268239), Paul Antoine Salin (821437), Régis Parmentier (821436), Nicolas Fraize (821434), Jennifer Ansoud-Lerouge (821435), Gaël Malleret (821438), Mickaël Antoine Joseph (821433), Sébastien Arthaud (561600), Christelle Peyron (2131)   +9 more
core   +1 more source

Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024

ELECTROPHORESIS, Volume 46, Issue 13-14, Page 829-862, July 2025.
ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of ...
Peter C. Hauser, Pavel Kubáň
wiley   +1 more source

The effect of treadmill running on passive avoidance learning in animal model of Alzheimer disease

International Journal of Preventive Medicine, 2013
Background : Alzheimer′s disease was known as a progressive neurodegenerative disorder in the elderly and is characterized by dementia and severe neuronal loss in the some regions of brain such as nucleus basalis magnocellularis.
Nasrin Hosseini, Hojjatallah Alaei, Parham Reisi, Maryam Radahmadi   +3 more
doaj  

Transient DREADD Manipulation of the Dorsal Dentate Gyrus in Rats Impairs Initial Learning of Place‐Outcome Associations

Hippocampus, Volume 35, Issue 3, May 2025.
ABSTRACT The dentate gyrus subfield of the hippocampus is thought to be critically involved in the disambiguation of similar episodic experiences and places in a context‐dependent manner. However, most empirical evidence has come from lesion and gene knock‐out studies in rodents, in which the dentate gyrus is permanently perturbed and compensation of ...
J. Lim, A. Souiki, P. Ahmad, C. A. Oomen, G. J. Huis in ’t Veld, C. S. Lansink, C. M. A. Pennartz, U. Olcese   +7 more
wiley   +1 more source

Early‐Life Ventral Hippocampal Lesion and Circadian Disruption Result in Altered Behavior in Adult Mice in a Sex‐Dependent Manner

European Journal of Neuroscience, Volume 61, Issue 9, May 2025.
Schizophrenia (SZ) may arise because of the interaction of risk factors acting during neurodevelopment. In mice, we show that abnormal ventral hippocampal development interacts with circadian disruption during adolescence to alter behavior relevant to SZ.
Ahmed A. Bouteldja, Lianne A. Marceau, Lalit K. Srivastava, Nicolas Cermakian   +3 more
wiley   +1 more source

The Effects of Mild Forced Treadmill Exercise and GABA-B Agonist on Locomotor Activity and Anxiety-Behavior in Rats with Striatum Dysfunction

Annals of Applied Sport Science, 2017
Background. the basal ganglia’s circuit dysfunction has a major role in a range of movement disorders. Some evidence has shown that exercise can improve performance, especially locomotor activity after brain injuries.
Shaghayegh Modaberi, Mehdi Shahbazi, Nasser Naghdi, Abolfazl Bagherzadeh   +3 more
doaj  

Visual Exploration and the Primate Hippocampal Formation

Hippocampus, Volume 35, Issue 1, January 2025.
ABSTRACT During the 1990s and early 2000s, research in humans and in the nonhuman primate model of human amnesia revealed that tasks involving free viewing of images provided an exceptionally sensitive measure of recognition memory. Performance on these tasks was sensitive to damage restricted to the hippocampus as well as to damage that included ...
Elizabeth A. Buffalo
wiley   +1 more source