Results 31 to 40 of about 2,517,895 (186)

Correction: Ameliorative Effects of a Combination of Baicalin, Jasminoidin and Cholic Acid on Ibotenic Acid-Induced Dementia Model in Rats

open access: yesPLoS ONE, 2013
Junying Zhang   +6 more
doaj   +4 more sources

Amanita muscaria: Ecology, Chemistry, Myths

open access: yesEncyclopedia, 2021
Amanita muscaria is the most emblematic mushroom in the popular representation. It is an ectomycorrhizal fungus endemic to the cold ecosystems of the northern hemisphere.
Quentin Carboué, Michel Lopez
doaj   +1 more source

MRI Overestimates Excitotoxic Amygdala Lesion Damage in Rhesus Monkeys

open access: yesFrontiers in Integrative Neuroscience, 2017
Selective, fiber-sparing excitotoxic lesions are a state-of-the-art tool for determining the causal contributions of different brain areas to behavior. For nonhuman primates especially, it is advantageous to keep subjects with high-quality lesions alive ...
Benjamin M. Basile   +4 more
doaj   +1 more source

The Discovery and Characterization of Targeted Perikaryal-Specific Brain Lesions With Excitotoxins

open access: yesFrontiers in Neuroscience, 2020
The neurotoxic action of glutamic acid was first described by Lucas and Newhouse, who demonstrated neural degeneration in the inner layers of the neonatal mouse retina after systemic treatment with L-glutamate.
Joseph T. Coyle, Robert Schwarcz
doaj   +1 more source

In vivo co-ordinated interactions between inhibitory systems to control glutamate mediated hippocampal excitability. [PDF]

open access: yes, 2013
We present an overview of the long-term adaptation of hippocampal neurotransmission to cholinergic and GABAergic deafferentation caused by excitotoxic lesion of the medial septum.
Rodríguez Allué, Manuel José   +3 more
core   +1 more source

Human Neural Stem Cells Genetically Modified to Express Human Nerve Growth Factor (NGF) Gene Restore Cognition in the Mouse with Ibotenic Acid-Induced Cognitive Dysfunction

open access: yesCell Transplantation, 2012
Alzheimer's disease (AD) is characterized by degeneration and loss of neurons and synapses throughout the brain, causing the progressive decline in cognitive function leading to dementia. No effective treatment is currently available. Nerve growth factor
Hong J. Lee   +5 more
doaj   +1 more source

Effects of bilateral anterior agranular insula lesions on food anticipatory activity in rats. [PDF]

open access: yesPLoS ONE, 2017
Food anticipatory activity (FAA) refers to a daily rhythm of locomotor activity that emerges under conditions of food restriction, whereby animals develop an intense, predictable period of activity in the few hours leading up to a predictable, daily ...
Alex M Gavrila   +3 more
doaj   +1 more source

 Pseudosperma arenarium (Inocybaceae), a new poisonous species from Eurasia, based on morphological, ecological, molecular and biochemical evidence [PDF]

open access: yesMycoKeys, 2022
In this study, Pseudosperma arenarium is proposed as a new species, based on morphological, ecological, molecular and biochemical evidence. The new species grows on sandy ground under Populus and Pinus sylvestris in north-western China and northern ...
Ya-Ya Yan   +6 more
doaj   +3 more sources

Neurotoxic Dorsal CA1 Lesions versus 4 VO Ischaemic Lesions: Behavioural Comparisons

open access: yesBehavioural Neurology, 1999
Anterograde amnesia, a common consequence of transient cerebral ischaemia, has been attributed to cell loss in the hippocampal CA1 subfield. However, variable, widespread damage outside hippocampal CA1 can also occur following ischaemia.
J. A. Nunn, J. A. Gray, H. Hodges
doaj   +1 more source

Studies on Acetylenic Compounds. XLIII. Synthesis of Ibotenic Acid.

open access: yesChemical and Pharmaceutical Bulletin, 1966
Ibotenic acid (α-amino-3-hydroxy-5-isoxazoleacetic acid monohydrate) (I), a flycidal amino acid isolated from Amanitae fungi, was synthesized. The reaction of ethyl 4, 4-diethoxytetrolate (V) with hydroxylamine in the presence of alkali gave 3-hydroxy-5-isoxazolecarboxaldehyde diethyl acetal (VI), which was hydrolyzed with 50% AcOH to the corresponding
Kishida, Yukichi   +4 more
openaire   +2 more sources

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