Results 21 to 30 of about 2,517,895 (186)

A Revised Model for Muscarine Biosynthesis Involving Lysine Trimethylation. [PDF]

Angew Chem Int Ed Engl
The fatal mushroom toxin l‐(+)‐muscarine is one of the most prominent natural products. We elucidated its biosynthetic origin in the sweating mushroom Collybia rivulosa based on incorporation of stable isotope‐labeled compounds and extensive mass spectrometric analyses.
Dörner S, Rogge K, Trottmann F, Hertweck C, Hoffmeister D.   +4 more
europepmc   +3 more sources

Mycotoxins in Basidiomycete Mycelium and Fruiting Bodies: Implications for Eu Novel Food Assessment and Selected International Regulatory Frameworks. [PDF]

Compr Rev Food Sci Food Saf
ABSTRACT Advances in technology have enabled the efficient and sustainable production of basidiomycete vegetative mycelium, particularly from Pleurotus species, as a novel food source. However, mycelium has yet to receive regulatory approval in many global markets, requiring a better understanding of factors affecting its safety.
Berglund NEW, Lankinen PV, Mikkonen KS.
europepmc   +2 more sources

Synthesis and pharmacology of N-alkylated derivatives of the excitotoxin ibotenic acid

Bioorganic & Medicinal Chemistry Letters, 1998
Three amino-alkylated derivatives of the naturally occurring excitatory amino acid (EAA) receptor agonist ibotenic acid (Ibo) have been synthesized and tested pharmacologically.
Madsen, U, Dumpis, M A, Bräuner-Osborne, Hans, Piotrovsky, L B   +3 more
core   +4 more sources

Mediodorsal thalamus lesion increases paradoxical sleep in rats [PDF]

Sleep Science, 2021
Introduction: The mediodorsal thalamic nucleus has extensive connections with prefrontal cortex, which is considered as seat of cognition. It also receives connections from sleep-wakefulness regulating areas in the brainstem and ...
S N Sriji, Nasreen Akhtar, Hruda Nanda Mallick   +2 more
doaj   +1 more source

Equipped for success: genomes and metabolomes of the European Amanita muscaria are conserved in its novel South African range. [PDF]

New Phytol
Summary Plants and soils have been moved around the world for centuries, but invasive mushrooms receive scant attention. The Amanita muscaria species complex was introduced to South Africa in the context of forestry, but its origins, ecology and recent evolution are unstudied. We sequenced the genomes of 24 Northern and Southern Hemisphere A. muscaria,
Nickles GR, Stokes CK, Narh DL, Lynn KMT, Fuqua SR, Bryan C, Allen BM, Bivins CP, Woo Bok J, Brewer JS, Buthelezi ST, Clark JPRM, Coon KL, Corby LR, Coetzee MPA, Dewing C, Duong TA, Harris MA, Keller NP, Kopotsa K, Lane FA, Nichols HL, Nieuwoudt A, Nuñez MA, Medina Munoz ME, Park SC, Pham NQ, Ryan KT, Solís M, Vilgalys R, Wallace JM, Wang YW, Wingfield BD, Wingfield MJ, Worley TK, Zallek TA, Zamanian M, Hoeksema JD, Drott MT, Pringle A.   +39 more
europepmc   +2 more sources

Confirmation of the Enhancement Effect of ANCE Treatment on Functional Recovery of Manual Dexterity From Primary Motor Cortex (M1) Lesion in Adult Macaque Monkeys. [PDF]

Brain Behav
Together, an earlier pilot study and the current confirmatory study show that an autologous cellular therapy promotes beneficial, significant enhancement of manual dexterity recovery after lesion of the primary motor cortex. ABSTRACT Introduction A pilot study provided preliminary evidence indicating that peri‐lesional adult autologous neural cell ...
Roux C, Savidan J, Brunet JF, Bloch J, Rouiller EM, Schmidlin E, Kaeser M.   +6 more
europepmc   +2 more sources

The contribution of the lateral posterior and anteroventral thalamic nuclei on spontaneous recurrent seizures in the pilocarpine model of epilepsy [PDF]

Arquivos de Neuro-Psiquiatria, 2002
The pilocarpine model of epilepsy in rats is characterised by the occurrence of spontaneous seizures (SRSs) during the chronic period that recur 2-3 times per week during the whole animal life.
Fulvio Alexandre Scorza, Ricardo Mario Arida, Margareth Priel, Lineu Calderazzo, Esper Abrão Cavalheiro   +4 more
doaj   +1 more source

Five new species of Inosperma from China: Morphological characteristics, phylogenetic analyses, and toxin detection

Frontiers in Microbiology, 2022
Many species of Inosperma cause neurotoxic poisoning in humans after consumption around the world. However, the toxic species of Inosperma and its toxin content remain unclear.
Sai-Nan Li, Fei Xu, Pan Long, Feng Liu, Ping Zhang, Yu-Guang Fan, Zuo-Hong Chen   +6 more
doaj   +1 more source

Synthesis of [³H]muscimol. [PDF]

J Labelled Comp Radiopharm
A novel synthetic approach for the preparation of [3H]muscimol (48.3 Ci/mmol, 1.8 TBq/mmol) based on the reduction of a suitably protected amide precursor using in situ generated tritioborane (BT3·THF) is reported. The method avoids the use of bulk tritiated water employed in established synthetic protocols and enables safe, reliable, and efficient ...
Kriegelstein M, Marek A.
europepmc   +2 more sources

The Deceptive Mushroom: Accidental Amanita muscaria Poisoning

European Journal of Case Reports in Internal Medicine, 2021
Amanita muscaria is considered to be one of the most remarkable and beautiful mushrooms. It has a red or orange cap covered with small white plaques and its distinctive appearance makes accidental and severe intoxication very rare.
Francesca Irene Rampolli, Premila Kamler, Claudio Carnevale Carlino, Francesca Bedussi   +3 more
doaj   +1 more source