Results 71 to 80 of about 1,288 (185)

871. Oral Ibrexafungerp Outcomes by Fungal Disease in Patients from an Interim Analysis of a Phase 3 Open-label Study (FURI)

open access: yesOpen Forum Infectious Diseases, 2022
Background There are limited oral treatment options for patients with fungal infections who fail currently available antifungals or have an infection caused by resistant organisms.
G. Thompson   +4 more
semanticscholar   +1 more source

Nine Things Genomics Can Tell Us About Candida auris [PDF]

open access: yes, 2020
FUNDING RF was supported by MRC grant MR/N006364/2 and a Wellcome Trust Seed Award (215239/Z/19/Z). ACKNOWLEDGMENTS We would like to give thanks to Carolina Coelho for helpful discussions and assistance with Figure 1 and Jose Muñoz for valuable feedback ...
Childers, Delma S   +2 more
core   +1 more source

Rezafungin—mechanisms of action, susceptibility and resistance: Similarities and differences with the other echinocandins [PDF]

open access: yes, 2020
Rezafungin (formerly CD101) is a new β-glucan synthase inhibitor that is chemically related with anidulafungin. It is considered the first molecule of the new generation of long-acting echinocandins. It has several advantages over the already approved by
Garcia, Guillermo Manuel
core   +1 more source

Ibrexafungerp Demonstrates In Vitro Activity against Fluconazole-Resistant Candida auris and In Vivo Efficacy with Delayed Initiation of Therapy in an Experimental Model of Invasive Candidiasis

open access: yesAntimicrobial Agents and Chemotherapy, 2021
Candida auris is an emerging pathogen that has rapidly spread to many countries on multiple continents. Invasive infections caused by this species are associated with significant mortality, and treatment options are limited due to antifungal resistance ...
N. Wiederhold   +6 more
semanticscholar   +1 more source

Targeting Staphylococcus aureus Biofilms Through Aurisin Derivatives From Neonothopanus nambi of African Origin

open access: yesChemistry &Biodiversity, Volume 23, Issue 2, February 2026.
This study describes the isolation and characterization of potent bioactive compounds from the fungal strain Neonothopanus nambi, followed by structural elucidation. The compounds shown are dimeric aristolane‐type sesquiterpenoids, identified as aurisins D (1) and B (2).
Syeda J. Khalid   +8 more
wiley   +1 more source

Topical Treatment of Recurrent Vulvovaginal Candidiasis: An Expert Consensus

open access: yesWomen's Health Reports, 2022
Background: Recurrent vulvovaginal candidiasis (RVVC), defined as three or more confirmed infections over 1 year, occurs in up to 10% of women. In these women, the objective is often symptomatic control rather than mycologic cure.
Nancy A. Phillips   +4 more
doaj   +1 more source

Epidemiology and Outcomes of Sporotrichosis: A Descriptive Real‐World Analysis From a Global Cohort

open access: yesMycoses, Volume 69, Issue 2, February 2026.
ABSTRACT Background Sporotrichosis is a dimorphic fungal infection of increasing global relevance. Although usually cutaneous or lymphocutaneous, disseminated disease occurs in immunocompromised hosts. Large‐scale data on its epidemiology, treatment and outcomes remain limited. Objectives To characterise the clinical features, comorbidities, antifungal
Samantha Schapiro   +8 more
wiley   +1 more source

Hope in the Treatment of Candida Vaginitis: Ibrexafungerp

open access: yesTürk Mikrobiyoloji Cemiyeti Dergisi, 2021
Candida vaginitis (CV) is a neglected but growing public health problem. It is estimated that three out of four women have had at least one CV attack. The diagnosis and treatment of CV is often inadequate due to the tendency of women to self-diagnose and use over-the-counter drugs when they have vaginal or vulvar complaints, and clinicians plan ...
openaire   +1 more source

Candida auris in Austria—What Is New and What Is Different

open access: yesJournal of Fungi, 2023
Candida auris is a novel and emerging pathogenic yeast which represents a serious global health threat. Since its first description in Japan 2009, it has been associated with large hospital outbreaks all over the world and is often resistant to more than
Kathrin Spettel   +10 more
doaj   +1 more source

Terapêutica antifúngica: novas moléculas, novas formas de administração e diferentes estratégias para alcançar a toxicidade seletiva [PDF]

open access: yes, 2021
Nos últimos anos verificou-se um aumento das infeções fúngicas invasivas, devido ao aumento da esperança de vida e do número de doentes imunodeprimidos e ao aparecimento de resistência aos antifúngicos.
Moreira, Marta Alexandra Macedo
core  

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