Results 91 to 100 of about 1,203 (200)

Lactams Exhibit Potent Antifungal Activity Against Monospecies and Multispecies Interkingdom Biofilms on a Novel Hydrogel Skin Model

APMIS, Volume 133, Issue 1, January 2025.
ABSTRACT Infections of intact and damaged skin barriers and keratin are frequently associated with complex biofilm communities containing bacteria and fungi, yet there are limited options for successful management. This study intended to focus on the utility of some novel proprietary lactam molecules, quorum sensing (QS)–derived halogenated furanones ...
Hafsa Abduljalil, Om Alkhir Alshanta, Safa Chougule, Mark Butcher, Bryn Short, William McLean, Neil Parry, Joanne O'Keeffe, Gordon Ramage   +8 more
wiley   +1 more source

Exploring the Depths of Cryptic Aspergillosis: Species Variability, Clinical Spectrum, Diagnostic Quandaries and Therapeutic Options [PDF]

Journal of Clinical and Diagnostic Research
Cryptic aspergillosis, characterised by infections caused by non classical Aspergillus species, presents unique challenges in clinical management due to species variability, diverse clinical manifestations, diagnostic complexities, and limited treatment ...
Almas Fathima Upaisal, Anupma Jyoti Kindo   +1 more
doaj   +1 more source

The Significance of Mono‐ and Dual‐Effective Agents in the Development of New Antifungal Strategies

Chemical Biology &Drug Design, Volume 105, Issue 1, January 2025.
The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates.
Cengiz Zobi, Oztekin Algul
wiley   +1 more source

Research progress of hydrogels in the prevention of pelvic inflammatory disease

MedComm – Biomaterials and Applications, Volume 3, Issue 4, December 2024.
This image summarizes pathogens and therapeutic interventions for pelvic inflammatory disease. We summarize the intrinsic properties of hydrogels and the application methods used in vagina and urinary tract infections. Abstract Pelvic inflammatory disease (PID) is a critical global health concern with the potential to lead to adverse outcomes ...
Yile Xiao, Teng Ma, Haoming Wu, Qiao Su, Yayu Zhou, Bingnan Zhou, Keyi Yang, Zhengguang Pu, Wanyue Feng, Xin Yong, Huili Zhu, Xulin Hu   +11 more
wiley   +1 more source

Multidrug resistance mechanisms and therapeutic strategies in Candida auris [PDF]

In recent years, Candida auris has emerged as a formidable global health threat due to its multidrug resistance, high transmissibility in healthcare settings, and diagnostic challenges. Unlike most Candida species, C. auris can colonize the skin, persist
Alkaabi, Sara
core   +2 more sources

The Candida auris Infection After the COVID‐19 Pandemic Seems to be an Urgent Public Health Emergency: A Call to Attention

Health Science Reports, Volume 7, Issue 11, November 2024.
Abstract Background and Aims Inconsequential diseases can sometimes become extremely dangerous through mutation. Antifungal resistance has increased by 24%, and resistance only due to Candida auris (C. auris) species have increased by 60%. Here, we aimed to assess the knowledge of antifungal treatment and preventative measures to mitigate the ...
Md. Ashrafur Rahman, Evangelos Victoros, Yeasna Shanjana, Marie Roke Thomas, Md. Rabiul Islam   +4 more
wiley   +1 more source

Overcoming Global Antifungal Challenges: Medical and Agricultural Aspects [PDF]

The prevalence of fungal infections and contamination has increased alarmingly over the past decade, posing a significant threat to human health and the food supply and negatively affecting welfare.
Galgóczi László Norbert
core   +1 more source

Effect of Star Topology Versus Linear Polymers on Antifungal Activity and Mammalian Cell Toxicity

Macromolecular Bioscience, Volume 24, Issue 5, May 2024.
Synthetic polymers inspired by natural antimicrobial peptides have shown promise for the treatment of fungal infections. The present study compares linear to star‐like topology of amphiphilic, positively charged polymers. A low‐Xn 3‐arm polymer shows favourable activity against Candida spp. and biocompatibility with fibroblasts.
Sebastian Schaefer, Daniele Melodia, Nathaniel Corrigan, Megan Denise Lenardon, Cyrille Boyer   +4 more
wiley   +1 more source

Primary antifungal prophylaxis in hematological malignancies. Updated clinical practice guidelines by the European Conference on Infections in Leukemia (ECIL). [PDF]

At the 10th European Conference on Infections in Leukaemia (ECIL), the guidelines for antifungal prophylaxis in pediatric and adult patients with hematological malignancies (HM) were updated and some changes introduced.
Blennow, O., Blijlevens, N.M.A., Busca, A., Cordonnier, C., Lamoth, F., Maertens, J., Maschmeyer, G., Pagano, L., Spadea, M., Xhaard, A.   +9 more
core   +1 more source

FUNGAL INFECTIONS ASSOCIATED WITH COVID-19 [PDF]

, 2021
To study fungal infections such as Mucormycosis, Aspergillosis, Candidiasis, Cryptococcosis associated with Covid-19. A detailed study was done with the information gathered from the articles in specified databases, online sources, and online published ...
AGARWAL, RICHA, ASIJA, RAJESH, SHARMA, ANTA, TANWAR, SONIKA   +3 more
core   +1 more source