Results 31 to 40 of about 208 (88)

The Telomeric Repeats of Human Herpesvirus 6A (HHV-6A) Are Required for Efficient Virus Integration [PDF]

, 2016
Human herpesvirus 6A (HHV-6A) and 6B (HHV-6B) are ubiquitous betaherpesviruses that infects humans within the first years of life and establishes latency in various cell types.
Flamand, Louis, Gravel, Annie, Kaufer, Benedikt B., Mori, Yasuko, Pirzer, Fabian, Sanyal, Anirban, Wallaschek, Nina   +6 more
core   +3 more sources

Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6

BMC Genomics, 2018
Background Human herpesvirus-6A and -6B (HHV-6) are betaherpesviruses that reach > 90% seroprevalence in the adult population. Unique among human herpesviruses, HHV-6 can integrate into the subtelomeric regions of human chromosomes; when this occurs in ...
Alexander L. Greninger, Giselle M. Knudsen, Pavitra Roychoudhury, Derek J. Hanson, Ruth Hall Sedlak, Hong Xie, Jon Guan, Thuy Nguyen, Vikas Peddu, Michael Boeckh, Meei-Li Huang, Linda Cook, Daniel P. Depledge, Danielle M. Zerr, David M. Koelle, Soren Gantt, Tetsushi Yoshikawa, Mary Caserta, Joshua A. Hill, Keith R. Jerome   +19 more
doaj   +1 more source

Maternal natural killer cells at the intersection between reproduction and mucosal immunity [PDF]

, 2021
: Many maternal immune cells populate the decidua, which is the mucosal lining of the uterus transformed during pregnancy. Here, abundant natural killer (NK) cells and macrophages help the uterine vasculature adapt to fetal demands for gas and nutrients,
Colucci, Francesco, Shmeleva, Evgeniya V.   +1 more
core   +2 more sources

Clinical and etiological aspects of human Betaherpesvirus infection 6: a review [PDF]

, 2022
The literature review is devoted to the modern concept of human betaherpesvirus 6 (human herpesvirus 6; HHV-6). The analysis of the literature mainly for the last five years was carried out.
I. V. Babachenko, N. S. Tian, O. V. Goleva   +2 more
core   +2 more sources

The Eruptive Fevers at Sixes and Sevens. [PDF]

Open Access Emerg Med
Robert J Petrella1– 6 1Harvard Medical School, Boston, MA, USA; 2Department of Chemistry & Chemical Biology, Harvard University, Cambridge, MA, USA; 3Emergency Departments, CharterCARE Health Partners, Providence and North Providence, RI, USA; 4Emergency
Petrella RJ, Petrella RJ.
europepmc   +3 more sources

Comparative analysis of Roseoloviruses in humans, pigs, mice, and other species [PDF]

, 2019
Viruses of the ...
Bigley, Tarin M, Denner, Joachim, Kaufer, Benedikt B, Phan, Tuan L, Zhou, Xiaofeng, Zimmermann, Cosima   +5 more
core   +2 more sources

Viral Proteins U41 and U70 of Human Herpesvirus 6A Are Dispensable for Telomere Integration

Viruses, 2018
Human herpesvirus-6A and -6B (HHV-6A and -6B) are two closely related betaherpesviruses that infect humans. Upon primary infection they establish a life-long infection termed latency, where the virus genome is integrated into the telomeres of latently ...
Darren J. Wight, Nina Wallaschek, Anirban Sanyal, Sandra K. Weller, Louis Flamand, Benedikt B. Kaufer   +5 more
doaj   +1 more source

HHV-6A/B Integration and the Pathogenesis Associated with the Reactivation of Chromosomally Integrated HHV-6A/B

Viruses, 2017
Unlike other human herpesviruses, human herpesvirus 6A and 6B (HHV-6A/B) infection can lead to integration of the viral genome in human chromosomes. When integration occurs in germinal cells, the integrated HHV-6A/B genome can be transmitted to 50% of ...
Vanessa Collin, Louis Flamand
doaj   +1 more source

Evolutionary history of endogenous Human Herpesvirus 6 reflects human migration out of Africa [PDF]

, 2020
Human herpesvirus 6A and 6B (HHV-6) can integrate into the germline, and as a result, ∼70 million people harbor the genome of one of these viruses in every cell of their body. Until now, it has been largely unknown if 1) these integrations are ancient, 2)
Aimola, G, Aswad, A, Breuer, J, Charnock-Jones, DS, Greninger, AL, Hill, J, Huang, M-L, Kaufer, BB, Lager, S, Lassner, D, Parrish, NF, Roychoudhury, P, Schultheiss, H-P, Smith, GCS, Venturini, C, Wight, D, Xie, H, Zimmermann, C   +17 more
core  

Telomeres and Telomerase: Role in Marek’s Disease Virus Pathogenesis, Integration and Tumorigenesis [PDF]

, 2017
Telomeres protect the ends of vertebrate chromosomes from deterioration and consist of tandem nucleotide repeats (TTAGGG)n that are associated with a number of proteins.
Ahmed Kheimar, Benedikt Kaufer, Caselli, Darren Wight, Davison, Delecluse, Delecluse, Deng, Dobbelstein, Kaufer, Kishi, Lee, Parcells, Prusty, Renato Previdelli   +14 more
core   +3 more sources