Results 21 to 30 of about 6,884,741 (113)

Reactivation of a Transplant Recipient's Inherited Human Herpesvirus 6 and Implications to the Graft. [PDF]

J Infect Dis
Background The implications of inherited chromosomally integrated human herpesvirus 6 (iciHHV-6) in solid organ transplantation remain uncertain.
Hannolainen L, Pyöriä L, Pratas D, Lohi J, Skuja S, Rasa-Dzelzkaleja S, Murovska M, Hedman K, Jahnukainen T, Perdomo MF.   +9 more
europepmc   +2 more sources

Pityriasis rosea in der Schwangerschaft: Eine Fallserie und Literaturübersicht

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 20, Issue 7, Page 953-960, July 2022., 2022
Zusammenfassung Hintergrund und Zielsetzung Pityriasis rosea (PR), eine häufige Hauterkrankung bei jungen Erwachsenen, kann den Verlauf der Schwangerschaft und das ungeborene Kind nachteilig beeinträchtigen. Patienten und Methodik Sechsundvierzig schwangere Frauen mit PR, die zwischen 2003 und 2018 an der dermatologischen Universität vorstellig waren ...
Lena Wenger‐Oehn, Thomas Graier, Christina Ambros‐ Rudolph, Robert Müllegger, Christina Bittighofer, Peter Wolf, Angelika Hofer   +6 more
wiley   +1 more source

Fetal inheritance of chromosomally integrated human herpesvirus 6 predisposes the mother to pre-eclampsia. [PDF]

Nat Microbiol, 2020
Pre-eclampsia (typically characterized by new-onset hypertension and proteinuria in the second half of pregnancy) represents a major determinant of the global burden of disease1,2.
Gaccioli F, Lager S, de Goffau MC, Sovio U, Dopierala J, Gong S, Cook E, Sharkey A, Moffett A, Lee WK, Delles C, Venturini C, Breuer J, Parkhill J, Peacock SJ, Charnock-Jones DS, Smith GCS.   +16 more
europepmc   +2 more sources

Summary of the 11th International Conference on Human Herpesviruses‐6A, ‐6B, and ‐7

Journal of Medical Virology, Volume 92, Issue 1, Page 4-10, January 2020., 2020
Abstract The 11th International Conference on Human Herpesviruses (HHV)‐6A, ‐6B, and ‐7 was held in Quebec City, from 23 to 26 June 2019. It attracted 144 basic, translational, and clinical scientists from 20 countries. Important new information was presented regarding: the mechanisms of chromosomal integration for HHV‐6A and ‐6B; the biology of ...
Anthony L. Komaroff, Danielle M. Zerr, Louis Flamand   +2 more
wiley   +1 more source

The case of inherited chromosomal integrated human herpes virus type 6b in child with recurrent respiratory tract infections

Журнал инфектологии, 2020
The five years old boy with recurrent respiratory tract infections was under observation of infectiologist due to high levels of human herpes virus type 6 (HHV-6), found in patient’s blood and saliva during a few years.
M. A. Nikolsky, A. A. Vyazovaya, D. A. Lioznov, O. V. Narvskaya, N. N. Smirnova   +4 more
doaj   +1 more source

Chromosomal integration of HHV-6A during non-productive viral infection

Scientific Reports, 2017
Human herpesvirus 6A (HHV-6A) and 6B (HHV-6B) are two different species of betaherpesviruses that integrate into sub-telomeric ends of human chromosomes, for which different prevalence rates of integration have been reported.
Nitish Gulve, Celina Frank, Maximilian Klepsch, Bhupesh K. Prusty   +3 more
doaj   +1 more source

Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A

Frontiers in Microbiology, 2019
Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis.
Anthony J. Saviola, Cosima Zimmermann, Michael P. Mariani, Sylvia A. Signorelli, Diana L. Gerrard, Joseph R. Boyd, Darren J. Wight, Guillaume Morissette, Annie Gravel, Isabelle Dubuc, Louis Flamand, Benedikt B. Kaufer, Seth Frietze   +12 more
doaj   +1 more source

Viral Proteins U41 and U70 of Human Herpesvirus 6A Are Dispensable for Telomere Integration

Viruses, 2018
Human herpesvirus-6A and -6B (HHV-6A and -6B) are two closely related betaherpesviruses that infect humans. Upon primary infection they establish a life-long infection termed latency, where the virus genome is integrated into the telomeres of latently ...
Darren J. Wight, Nina Wallaschek, Anirban Sanyal, Sandra K. Weller, Louis Flamand, Benedikt B. Kaufer   +5 more
doaj   +1 more source

HHV-6A/B Integration and the Pathogenesis Associated with the Reactivation of Chromosomally Integrated HHV-6A/B

Viruses, 2017
Unlike other human herpesviruses, human herpesvirus 6A and 6B (HHV-6A/B) infection can lead to integration of the viral genome in human chromosomes. When integration occurs in germinal cells, the integrated HHV-6A/B genome can be transmitted to 50% of ...
Vanessa Collin, Louis Flamand
doaj   +1 more source

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

Cell Proliferation, Volume 58, Issue 11, November 2025.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far, Marziyeh Akbari, Mohammad Amin Habibi, Morteza Katavand, Sherko Nasseri   +4 more
wiley   +1 more source