Results 21 to 30 of about 161 (76)

Summary of the 11th International Conference on Human Herpesviruses‐6A, ‐6B, and ‐7

open access: yesJournal of Medical Virology, Volume 92, Issue 1, Page 4-10, January 2020., 2020
Abstract The 11th International Conference on Human Herpesviruses (HHV)‐6A, ‐6B, and ‐7 was held in Quebec City, from 23 to 26 June 2019. It attracted 144 basic, translational, and clinical scientists from 20 countries. Important new information was presented regarding: the mechanisms of chromosomal integration for HHV‐6A and ‐6B; the biology of ...
Anthony L. Komaroff   +2 more
wiley   +1 more source

The case of inherited chromosomal integrated human herpes virus type 6b in child with recurrent respiratory tract infections

open access: yesЖурнал инфектологии, 2020
The five years old boy with recurrent respiratory tract infections was under observation of infectiologist due to high levels of human herpes virus type 6 (HHV-6), found in patient’s blood and saliva during a few years.
M. A. Nikolsky   +4 more
doaj   +1 more source

Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6

open access: yesBMC Genomics, 2018
Background Human herpesvirus-6A and -6B (HHV-6) are betaherpesviruses that reach > 90% seroprevalence in the adult population. Unique among human herpesviruses, HHV-6 can integrate into the subtelomeric regions of human chromosomes; when this occurs in ...
Alexander L. Greninger   +19 more
doaj   +1 more source

Latency, Integration, and Reactivation of Human Herpesvirus-6

open access: yesViruses, 2017
Human herpesvirus-6A (HHV-6A) and human herpesvirus-6B (HHV-6B) are two closely related viruses that infect T-cells. Both HHV-6A and HHV-6B possess telomere-like repeats at the terminal regions of their genomes that facilitate latency by integration into
Shara N. Pantry, Peter G. Medveczky
doaj   +1 more source

Chromosomal integration of HHV-6A during non-productive viral infection

open access: yesScientific Reports, 2017
Human herpesvirus 6A (HHV-6A) and 6B (HHV-6B) are two different species of betaherpesviruses that integrate into sub-telomeric ends of human chromosomes, for which different prevalence rates of integration have been reported.
Nitish Gulve   +3 more
doaj   +1 more source

Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A

open access: yesFrontiers in Microbiology, 2019
Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis.
Anthony J. Saviola   +12 more
doaj   +1 more source

Viral Proteins U41 and U70 of Human Herpesvirus 6A Are Dispensable for Telomere Integration

open access: yesViruses, 2018
Human herpesvirus-6A and -6B (HHV-6A and -6B) are two closely related betaherpesviruses that infect humans. Upon primary infection they establish a life-long infection termed latency, where the virus genome is integrated into the telomeres of latently ...
Darren J. Wight   +5 more
doaj   +1 more source

HHV-6A/B Integration and the Pathogenesis Associated with the Reactivation of Chromosomally Integrated HHV-6A/B

open access: yesViruses, 2017
Unlike other human herpesviruses, human herpesvirus 6A and 6B (HHV-6A/B) infection can lead to integration of the viral genome in human chromosomes. When integration occurs in germinal cells, the integrated HHV-6A/B genome can be transmitted to 50% of ...
Vanessa Collin, Louis Flamand
doaj   +1 more source

The proteomic and metabolomic signature of inherited chromosomally integrated HHV‐6 and its role in all‐cause dementia and mortality risk: The UK Biobank study

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 3, July/September 2026.
Abstract OBJECTIVE To examine associations of inherited chromosomally integrated human herpesvirus 6 (iciHHV‐6) with incident dementia and mortality, characterize proteomic and metabolomic correlates of carrier status, and evaluate whether these biomarkers relate to dementia and mortality risk.
May A. Beydoun   +10 more
wiley   +1 more source

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