Results 31 to 40 of about 77,918,908 (98)
Summary of the 11th International Conference on Human Herpesviruses‐6A, ‐6B, and ‐7
Abstract The 11th International Conference on Human Herpesviruses (HHV)‐6A, ‐6B, and ‐7 was held in Quebec City, from 23 to 26 June 2019. It attracted 144 basic, translational, and clinical scientists from 20 countries. Important new information was presented regarding: the mechanisms of chromosomal integration for HHV‐6A and ‐6B; the biology of ...
Anthony L. Komaroff +2 more
wiley +1 more source
The five years old boy with recurrent respiratory tract infections was under observation of infectiologist due to high levels of human herpes virus type 6 (HHV-6), found in patient’s blood and saliva during a few years.
M. A. Nikolsky +4 more
doaj +1 more source
Fetal inheritance of chromosomally integrated human herpesvirus 6 predisposes the mother to pre-eclampsia. [PDF]
Pre-eclampsia (typically characterized by new-onset hypertension and proteinuria in the second half of pregnancy) represents a major determinant of the global burden of disease1,2.
Lee, Wai Kwong, +16 more
core +2 more sources
Evolutionary analysis of exogenous and integrated HHV-6A/HHV-6B populations [PDF]
Human betaherpesviruses 6A and 6B (HHV-6A and HHV-6B) are highly prevalent in human populations. The genomes of these viruses can be stably integrated at the telomeres of human chromosomes and be vertically transmitted (inherited chromosomally integrated
M Sironi +4 more
core +1 more source
Viral Proteins U41 and U70 of Human Herpesvirus 6A Are Dispensable for Telomere Integration
Human herpesvirus-6A and -6B (HHV-6A and -6B) are two closely related betaherpesviruses that infect humans. Upon primary infection they establish a life-long infection termed latency, where the virus genome is integrated into the telomeres of latently ...
Darren J. Wight +5 more
doaj +1 more source
Unlike other human herpesviruses, human herpesvirus 6A and 6B (HHV-6A/B) infection can lead to integration of the viral genome in human chromosomes. When integration occurs in germinal cells, the integrated HHV-6A/B genome can be transmitted to 50% of ...
Vanessa Collin, Louis Flamand
doaj +1 more source
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far +4 more
wiley +1 more source
Investigating the Consequences of Herpesvirus Integration into Host Telomeres
The two species of human herpesvirus 6 (HHV-6A and HHV-6B) and chicken Marek's disease virus (MDV) include sequences homologous to (TTAGGG)n within their genomes and have the capacity to integrate into telomeres in their hosts.
Michael L. Wood (3007005)
core +1 more source
Human herpesvirus-6A and -6B (HHV-6) are betaherpesviruses that reach >90% seroprevalence in the adult population. Unique among human herpesviruses, HHV-6 can integrate into the subtelomeric regions of human chromosomes; when this occurs in germ line ...
Linda Cook +19 more
core +1 more source
Inherited chromosomally integrated HHV-6 demonstrates tissue-specific RNA expression in vivo [PDF]
Thesis (Master's)--University of Washington, 2019Human herpesvirus-6A and 6B (HHV-6A, HHV-6B) are highly prevalent viruses unique in that they, besides Epstein-Barr virus, are the only human herpesviruses capable of chromosomal integration.
Peddu, Vikas
core

