Human Herpesvirus 6 and Malignancy: A Review [PDF]
, 2018 In order to determine the role of human herpesvirus 6 (HHV-6) in human disease, several confounding factors, including methods of detection, types of controls, and the ubiquitous nature of the virus, must be considered.
Dharam Ablashi +9 more
core +1 more source
HHV-6A infection induces amyloid-beta expression and activation of microglial cells. [PDF]
, 2019 BACKGROUND: The control of viral infections in the brain involves the activation of microglial cells, the macrophages of the brain that are constantly surveying the central nervous system, and the production of amyloid-beta (Aβ) as an anti-microbial ...
Bortolotti, Daria +4 more
core +1 more source
Differential Impacts of HHV-6A versus HHV-6B Infection in Differentiated Human Neural Stem Cells [PDF]
, 2022 Within the family Herpesviridae, sub-family β-herpesvirinae, and genus Roseolovirus, there areonly three human herpesviruses that have been described: HHV-6A, HHV-6B, and HHV-7.
Bahramian, Elham
core +3 more sources
Cell Proliferation, Volume 58, Issue 11, November 2025.CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far +4 more
wiley +1 more source
Characterization Of Higher Order Chromatin Structures And Chromatin States In Cell Models Of Human Herpesvirus Infection [PDF]
, 2021 Human herpesviruses are ubiquitous pathogens worldwide with 90% of the global population infected with one or more Human herpesviruses (HHV’s) by adulthood. All herpesviruses have three unique life cycle stages.
Mariani, Michael
core +1 more source
Lymphoproliferative syndromes associated with human herpesvirus-6A and human herpesvirus-6B [PDF]
, 2018 Human herpesvirus 6A and 6B (HHV-6A and HHV-6B) have been noted since their discovery for their T-lymphotropism. Although it has proven difficult to determine the extent to which HHV-6A and HHV-6B are involved in the pathogenesis of many diseases ...
Ablashi, Dharam +3 more
core +2 more sources
Inherited chromosomally integrated human herpesvirus 6: demographics and disease [PDF]
, 2016 Human herpesvirus (HHV) –6A and HHV-6B are unique among herpesviruses in their ability to integrate into the telomeres of human chromosomes and be inherited in a Mendelian fashion. Based on current data, inherited chromosomally integrated HHV-6 (iciHHV-6)
Bell, Adam Joseph
core
Characterisation of herpesviruses in KORA cohort and association with type 2 diabetes [PDF]
, 2021 Introduction: Herpesviruses are a class of highly prevalent and contagious DNA viruses with low pathogenicity. Type 2 diabetes is among the most important metabolic diseases with increasing worldwide prevalence and is one of the major risk factors for ...
Wölfle, Tim
core
Inherited Chromosomally Integrated Human Herpesvirus 6 and Breast Cancer [PDF]
, 2017 Background: Inherited chromosomally integrated human herpesvirus 6 (iciHHV-6) is a condition observed in approximately 1% of the population. Whether such a genetic alteration predisposes to cancer development in currently unknown.
Angela Brooks-Wilson +7 more
core +1 more source
Investigating the Consequences of Herpesvirus Integration into Host Telomeres
, 2023 The two species of human herpesvirus 6 (HHV-6A and HHV-6B) and chicken Marek's disease virus (MDV) include sequences homologous to (TTAGGG)n within their genomes and have the capacity to integrate into telomeres in their hosts.
Michael L. Wood (3007005)
core +1 more source