Results 91 to 100 of about 543,737 (387)

Large‐eddy simulations over Germany using ICON: a comprehensive evaluation

, 2017
Large‐eddy simulations (LES) with the new ICOsahedral Non‐hydrostatic atmosphere model (ICON) covering Germany are evaluated for four days in spring 2013 using observational data from various sources. Reference simulations with the established Consortium
Rieke Heinze, A. Dipankar, C. C. Henken, C. Moseley, O. Sourdeval, S. Trömel, Xinxin Xie, P. Adamidis, F. Ament, H. Baars, C. Barthlott, A. Behrendt, U. Blahak, S. Bley, Slavko Brdar, M. Brueck, S. Crewell, H. Deneke, P. Di Girolamo, Raquel Evaristo, J. Fischer, Christopher Frank, P. Friederichs, Tobias Göcke, Ksenia Gorges, L. Hande, M. Hanke, Akio Hansen, H. Hege, C. Hoose, T. Jahns, N. Kalthoff, D. Klocke, S. Kneifel, P. Knippertz, A. Kuhn, Thriza van Laar, A. Macke, V. Maurer, B. Mayer, C. Meyer, S. K. Muppa, R. Neggers, E. Orlandi, Florian Pantillon, B. Pospichal, N. Röber, L. Scheck, A. Seifert, P. Seifert, F. Senf, P. K. Siligam, C. Simmer, S. Steinke, B. Stevens, K. Wapler, M. Weniger, V. Wulfmeyer, G. Zängl, Dan Zhang, J. Quaas   +60 more
semanticscholar   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Designing an Adaptive Interface: Using Eye Tracking to Classify How Information Usage Changes Over Time in Partially Automated Vehicles [PDF]

, 2020
While partially automated vehicles can provide a range of benefits, they also bring about new Human Machine Interface (HMI) challenges around ensuring the driver remains alert and is able to take control of the vehicle when required.
Birrell, S., Jennings, P., Oliveira, L., Ulahannan, Arun   +3 more
core   +2 more sources

The iconicity toolbox: empirical approaches to measuring iconicity [PDF]

Language and Cognition, 2019
abstractGrowing evidence from across the cognitive sciences indicates that iconicity plays an important role in a number of fundamental language processes, spanning learning, comprehension, and online use. One benefit of this recent upsurge in empirical work is the diversification of methods available for measuring iconicity.
MOTAMEDI, Y, LITTLE, H, NIELSEN, A, SULIK, J   +3 more
openaire   +4 more sources

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Faktor Pemanfaatan Imunisasi Inactivated Polio Vaccine (IPV)

Jurnal Kesehatan, 2020
The low utilization of IPV immunization services in Palembang in 2017 was 66,7% while the national target was 95%. The purpose of this study was to determine the factors associated with the utilization of IPV immunization services in Palembang. The study
Icon Harizon, Misnaniarti Misnaniarti, Haerawati Idris   +2 more
doaj   +1 more source

ICON: Eosinophil Disorders [PDF]

World Allergy Organization Journal, 2012
SUMMARY Eosinophil disorders and related syndromes are a heterogeneous group of conditions characterized by marked persistent blood eosinophilia and involvement of one or more organ systems. The hypereosinophilic (HE) state is defined by a persistent eosinophil count exceeding 1.5 · 10 9 /L blood.
Valent, Peter, Klion, Amy, Rosenwasser, Lanny, Arock, Michel, Bochner, Bruce, Butterfield, Joe, Gotlib, Jason, Haferlach, T, Hellmann, A, Horny, H, Leiferman, Kristin, Metzgeroth, Georgia, Matsumoto, K, Reiter, Andreas, Roufosse, Florence, Rothenberg, Marc, Simon, Hans-Uwe, Sotlar, K, Vandenberghe, Peter, Weller, Peter, Gleich, Gerald   +20 more
openaire   +5 more sources

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

Good practices for the translation, cultural adaptation, and linguistic validation of clinician-reported outcome, observer-reported outcome, and performance outcome measures

Journal of Patient-Reported Outcomes, 2020
Within current literature and practice, the category of patient-reported outcome (PRO) measures has been expanded into the broader category of clinical outcome assessments (COAs), which includes the subcategory of PRO, as well as clinician-reported ...
Shawn McKown, Catherine Acquadro, Caroline Anfray, Benjamin Arnold, Sonya Eremenco, Christelle Giroudet, Mona Martin, Dana Weiss   +7 more
doaj   +1 more source

Health-related quality of life scores of metastatic pancreatic cancer patients responsive to first line chemotherapy compared to newly derived EORTC QLQ-C30 reference values

BMC Cancer, 2022
Background Metastatic pancreatic cancer (mPC) and its treatments significantly impact health-related quality of life (HRQoL). POLO, a randomized, double-blind, placebo-controlled phase 3 trial evaluated the efficacy of olaparib as maintenance therapy in ...
Suvina Amin, Seongjung Joo, Sandra Nolte, Hyun Kyoo Yoo, Nikunj Patel, Hilary F. Byrnes, Sara Costa-Cabral, Colin D. Johnson   +7 more
doaj   +1 more source