Results 81 to 90 of about 471,112 (353)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Iconic memory of icon? [PDF]

open access: yes, 1987
The objectives of the present commentary are to show that (1) one important theoretical property of iconic memory is inconsistent with a retinotopic icon, (2) data difficult for the notion of an icon do not necessarily challenge the notion of an iconic ...
Chow, Dr Siu L.
core  

Children's interactions with interactive toy technology [PDF]

open access: yes, 2003
Digital toys offer the opportunity to explore software scaffolding through tangible interfaces that are not bound to the desktop computer. This paper describes the empirical work completed by the CACHET (Computers and Children's Electronic Toys) project ...
Airey, S.   +3 more
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

We have a steak in it: Eliciting interventions to reduce beef consumption and its impact on biodiversity

open access: yesConservation Letters, 2020
Beef production is a major driver of biodiversity loss and greenhouse gas emissions globally, and multiple studies recommend reducing beef production and consumption.
Matthew J. Selinske   +5 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Content validity of a novel patient-reported and observer-reported outcomes assessment to evaluate ocular symptoms associated with infectious conjunctivitis in both adult and pediatric populations

open access: yesHealth and Quality of Life Outcomes, 2019
Background Acute infectious conjunctivitis is a common condition most frequently caused by viruses or bacteria. Clinical outcome assessments have been used to assess signs and symptoms of bacterial and viral conjunctivitis, but have not been evaluated ...
Sujata P. Sarda   +6 more
doaj   +1 more source

The Substitution Principle Revisited [PDF]

open access: yes, 2018
In their Anachronic Renaissance, Alexander Nagel and Christopher Wood identify two principles upon which, in fifteenth-century Europe, a work of art might establish its validity or authority: substitution and performance. It has become established wisdom
Stejskal, Jakub
core   +1 more source

iPod... icon

open access: yes, 2008
The iPod became, for a moment at least, iconic amongst those hand-held electronic devices with buttons and screens, noises and "connectivity" that proliferated at the beginning of the twenty-first century. This essay explores how the iPod, in becoming an unobtrusive memory machine as absent as an internal organ on the body of its user, provides a ...
openaire   +2 more sources

Iconics: Icon Evolution in Digitality

open access: yestripleC: Communication, Capitalism & Critique. Open Access Journal for a Global Sustainable Information Society, 2010
Image manipulation, archiving, and sharing are all critical technological aspects of Western culture and postmodern civilization. Consequently, creation, identification, dissemination, and proliferation of powerful images across media channels today indicate a burgeoning area of information technology.While words alone are capable of conveying adequate
openaire   +3 more sources

Home - About - Disclaimer - Privacy