Results 81 to 90 of about 60,513 (316)
UA-ICON with the NWP physics package (version ua-icon-2.1): mean state and variability of the middle atmosphere [PDF]
Geoscientific Model DevelopmentThe Icosahedral Nonhydrostatic (ICON) general circulation model with an upper-atmospheric extension (UA-ICON) in the configuration with the physics package for numerical weather prediction (NWP) is presented with optimized parameter settings for the non ...
M. Kunze +8 more
doaj +1 more source
Nauka, bezbednost, policija, 2016 The paper first considers certain issues related to the Orthodox icons, and points out to their specific features that differentiate them in relation to any other religious picture. As a hallmark of Orthodox religion, icons represent the artistic expression of theology and service of the Church, whose nature and meaning were defined at the Seventh ...
openaire +4 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
CeROArt, 2009 This article is based on the thesis „Icon Forgery. A historical, ethical and technological reflection” by the author, which explains, when is an Icon genuine or a forgery. In doing so, the terms Icon and Icon-copy will be defined by taking the aspects of the religious significance as well as the historical development into consideration.
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Dates of the parts of P. S. Pallas's ‘Icones Insect. p. Ross. Sibir.’ and ‘Nov. spec. Quadr. Glirium’ [PDF]
, 1891 C. Davies Sherborn
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, 2017 My ambition in these few pages is to draw attention to the three types of icons identified by Peirce - images, diagrams or metaphors - which, I shall be arguing, must be reckoned with when examining the processes by which human agency invents (or re-invents) the real. In order to illustrate these types of icon, I shall propose a few exemple.
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Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source