Results 81 to 90 of about 448,633 (304)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
, 2008 The iPod became, for a moment at least, iconic amongst those hand-held electronic devices with buttons and screens, noises and "connectivity" that proliferated at the beginning of the twenty-first century. This essay explores how the iPod, in becoming an unobtrusive memory machine as absent as an internal organ on the body of its user, provides a ...
openaire +2 more sources
Iconics: Icon Evolution in Digitality
tripleC: Communication, Capitalism & Critique. Open Access Journal for a Global Sustainable Information Society, 2010 Image manipulation, archiving, and sharing are all critical technological aspects of Western culture and postmodern civilization. Consequently, creation, identification, dissemination, and proliferation of powerful images across media channels today indicate a burgeoning area of information technology.While words alone are capable of conveying adequate
openaire +3 more sources
Bhima in Postmodern Meaningfulness [PDF]
, 2012 The Bhīma character is the strongest character among the Panca Pandawas in the Mahabharata, this perception has been held since the classical age up to now, which made Bhīma becomes a cultural icon of the Archipelago.
I NYOMAN , LINGGIH
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Journal of Patient-Reported Outcomes, 2020 Within current literature and practice, the category of patient-reported outcome (PRO) measures has been expanded into the broader category of clinical outcome assessments (COAs), which includes the subcategory of PRO, as well as clinician-reported ...
Shawn McKown +7 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Students’ Attitudes and Perceptions on Xenophobia: A Study of a University in Durban
Journal of Student Affairs in Africa, 2019 The recurrence of xenophobic violence in South Africa has been attributed to the proliferation of antimigrant sentiments that stems from social, political, economic and cultural misconceptions and cleavages.
Olubunmi Damilola Akande +2 more
doaj +1 more source
Conservation Letters, 2020 Beef production is a major driver of biodiversity loss and greenhouse gas emissions globally, and multiple studies recommend reducing beef production and consumption.
Matthew J. Selinske +5 more
doaj +1 more source