Results 181 to 190 of about 40,233 (217)

Subchronic toxicity of chlorpropham (CIPC) in ICR mice

Food and Chemical Toxicology, 2000
Male and female ICR mice were given 0, 1875, 7500 or 30,000 ppm of chlorpropham (CIPC) in the diet for 13 weeks. Methemoglobin levels of male and female mice in the 7500 and 30,000 ppm groups were significantly elevated. Hemoglobin concentration, packed cell volume, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin ...
T, Fujitani, Y, Tada, A, Fujii, M, Kimura, M, Yoneyama   +4 more
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Subchronic toxicity of thiabendazole (TBZ) in ICR mice

Food and Chemical Toxicology, 1996
The subchronic toxic effects of thiabendazole (TBZ) administered in the diet at levels of 0 (control), 0.8 and 1.6% for 13 wk to male and female ICR mice were investigated. Mean body weights of male mice fed 0.8 or 1.6% TBZ showed a significant decrease compared with controls, except for wk 3 and 8 for mice fed 0.8% TBZ.
Y, Tada, T, Fujitani, M, Yoneyama
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Subacute toxicity of piperonyl butoxide in ICR mice

Toxicology, 1993
Piperonyl butoxide, alpha-[2-(2-butoxyethoxy)ethoxy]-4,5-methylenedioxy-2-propyltol uene, is a pesticide synergist. ICR mice of both sexes were maintained on diet containing 0, 0.1, 0.3 or 0.9% of piperonyl butoxide for 20 days. At the end of the experimental period, they were necropsied. Selected organs were weighed and serum chemistries were analyzed.
T, Fujitani, T, Tanaka, Y, Hashimoto, M, Yoneyama   +3 more
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Cyclophosphamide‐induced teratogenesis in ICR mice: The role of apoptosis

Teratogenesis, Carcinogenesis, and Mutagenesis, 1995
AbstractIt is known that programmed cell death (apoptosis) is an important physiological determinant of embryonic development. In parallel, it may be one of the major events involved in induced teratogenesis. The present study was designated to evaluate to what extent is apoptosis involved in the formation of some final abnormalities induced by ...
A, Torchinsky, S, Savion, M, Gorivodsky, J, Shepshelovich, Z, Zaslavsky, A, Fein, V, Toder   +6 more
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Subcutaneous toxicity of melittin-dKLA in ICR mice

Molecular & Cellular Toxicology, 2021
Melittin, a major component of honeybee venom, is known to possess anti-allergic, anti-inflammatory, anti-arthritis, and anti-cancer. Despite its great promise as an agent for various diseases, the therapeutic applications of melittin have been severely limited by its nonspecific cytotoxicity and hemolytic activity.
Jiham Sung, Yura Kim, Pei Fu Yu, Younsub Kim, Ik-Hwan Han, Hyunsu Bae   +5 more
openaire   +1 more source

The embryotoxic effects of ultrasound exposure in pregnant ICR mice

Teratology, 1983
AbstractThe embryotoxicity of ultrasound exposure during pregnancy was investigated in DUB:(ICR) mice. On day 0 of gestation (day of plug), pregnant mice were assigned to one of five groups: cage control, sham exposed (0 W/cm2), 0.05 W/cm2, 0.50 W/cm2, or 1.00 W/cm2.
C A, Kimmel, M E, Stratmeyer, W D, Galloway, J B, Laborde, N, Brown, F, Pinkavitch   +5 more
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Effects of Cow's Milk on Reproduction in ICR Male Mice

Biomedical and Environmental Sciences, 2009
To study the effects of Cow's milk on the reproduction in male mice.Twenty-four male mice were divided randomly into two groups: milk group (M) and control group (C). Each mouse was given 10 mL milk per day from 4 to 16 weeks in the group M. At the age of 17 weeks, all the mice were sacrificed.Serum testosterone was decreased in the group M (P=0.037 ...
Yu-Xia, Ma, Naoyuki, Ebine, Kazuo, Aoki, Masahiro, Kusunoki, Junichi, Misumi   +4 more
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Thiabendazole (TBZ) nephrotoxicity and recovery in ICR adult mice

Toxicology, 1994
The nephrotoxicity and recovery following administration of thiabendazole (TBZ) were investigated in ICR adult mice. A single oral administration of TBZ (500-2000 mg/kg body wt.) caused a dose-dependent proximal tubular necrosis in the kidney and increase in serum urea nitrogen 24 h after dosing.
Y, Tada, T, Fujitani, M, Yoneyama
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Developmental toxicity of orally administered thiabendazole in ICR mice

Food and Chemical Toxicology, 2001
Thiabendazole (TBZ) is a potent anthelmintic and fungicide used in the treatment of parasitic infections in humans and domestic animals and post-harvest protection of agricultural commodities. TBZ is not teratogenic or selectively foetotoxic in rats or rabbits, in contrast to several other benzimidazole derivatives. However, when administered orally to
G R, Lankas, T, Nakatsuka, Y, Ban, T, Komatsu, H, Matsumoto   +4 more
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Acetazolamide affects breathing differently in ICR and C57 mice

Respiratory Physiology & Neurobiology, 2006
Acetazolamide (ACZ) administration was compared on ventilation in outbred male ICR Swiss Webster (ICR) and inbred C57BL/6J (C57) mice, used in development of transgenic strains. We hypothesized that in both strains ACZ would affect breathing similarly. Mice received intraperitoneally vehicle and the next week ACZ (40 mg/kg), and were exposed to air for
Evelyn, Schlenker, Yijiang, Shi, Chris, Johnson, Joni, Wipf   +3 more
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