Results 191 to 200 of about 40,233 (217)
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Insights into modeling streptozotocin-induced diabetes in ICR mice
Lab Animal, 2009Streptozotocin (STZ)-induced diabetes in ICR mice is often used to model diabetes mellitus and its complications, as well as other pathologies. In studies of diabetes progression and effects of newly developed treatments, experimental results may be difficult to interpret because blood glucose levels (BGLs) of untreated diabetic control animals tend to
Yaron, Dekel +3 more
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Acute renal toxicity of thiabendazole (TBZ) in ICR mice
Food and Chemical Toxicology, 1992The acute toxic effects of thiabendazole [2-(4'-thiazolyl)benzimidazole; TBZ] on the kidneys of ICR mice were investigated. The mice were given 0, 250, 500 or 1000 mg TBZ/kg body weight by gavage (using olive oil as a vehicle), and the kidneys were subjected to pathological examination at 1, 3, 5 or 24 hr after dosing.
Y, Tada, T, Fujitani, M, Yoneyama
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Genetic effects of benzene and radiation in ICR and XGf mice
Cancer Letters, 1989X/Gf mice (a tumor-resistant strain) were compared with ICR mice (moderately tumor-sensitive) for their sensitivity to chromosomal damage caused by benzene, cyclophosphamide (CP), benzo(a)pyrene (BP) and radiation. There was no difference between strains in the level of micronucleus formation caused by BP, CP or radiation.
B L, Harper +3 more
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Ageing in irradiated and unirradiated germfree ICR mice
Experimental Gerontology, 1967Abstract The life span and incidence of disease were studied in germfree, conventional, and barrier ICR mice which had not been exposed to X-irradiation and in germfree and conventional male mice of the same strain which had been exposed to 600–900 R of X-radiaiton at 12 weeks of age.
H.E. Walburg, G.E. Cosgrove
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Thiabendazole induces urinary tract toxicity in male ICR mice
Toxicology, 2001Male ICR mice were administered thiabendazole (TBZ) in the diet at concentration of 0 (control), 0.8, 1.2 and 1.6% for 44 weeks. The mortality was 10, 6, 40 or 90% in control, 0.8, 1.2 or 1.6% TBZ group, respectively. In dead mice, the gross findings included the abnormalities of kidney such as atrophy, hydronephrosis or swelling in 2, 67, 95 or 96% of
Y, Tada +5 more
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SELENATE- AND SELENOMETHIONINE-INDUCED LEUKOPENIA IN ICR FEMALE MICE
Journal of Toxicology and Environmental Health, Part A, 1998The investigations reported here were conducted to gain a better understanding of the comparative toxicity of selenium. Sodium selenate and selenomethionine were administered to young adult ICR female mice. Peripheral leukocyte counts and ratios of agranulocyte (Ag) to granulocyte (G) leukocytes were determined from blood that was collected at ...
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Diurnal variation of cisplatin-induced renal toxicity in ICR mice
Biochemical and Biophysical Research CommunicationsCisplatin (CDDP) is a platinum-based anticancer drug widely prescribed for its effectiveness in treating various forms of cancer. However, its major side effect is nephrotoxicity. Although several methods have been developed to mitigate CDDP-induced nephrotoxicity, an optimal approach has yet to be established.
Sarah Tominaga +5 more
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Acquired Immunity to Nematospiroides dubius in ICR Mice
The Journal of Parasitology, 1973D W, Hosier, M D, Feller
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