Results 41 to 50 of about 40,233 (217)

Comparison of therapeutic responses to an anticancer drug in three stocks of ICR mice derived from three different sources

Laboratory Animal Research, 2017
Korl:ICR mice, established by the Korean National Institute of Food and Drug Safety Evaluation (NIFDS), are characterized based on their genetic variation, response to gastric injury, and response to constipation inducers.
Ji Eun Sung, Ji Eun Kim, Hyun Ah Lee, Woo Bin Yun, Jun Young Choi, Mi Rim Lee, Jin Ju Park, Hye Ryeong Kim, Bo Ram Song, Young Suk Jung, Kil Soo Kim, Dae Youn Hwang   +11 more
doaj   +1 more source

Degenerative Osteoarthrosis in Aged ICR Mice

Experimental Animals, 1986
The tibia of 117 aged ICR mice was examined histologically to provide further information on degenerative osteoarthrosis. Incidence of the lesion became higher in the male older than 480 days of age and in the female older than 450 days. Main gross changes were roughening of the articular surface, narrowing or focal thickening of the articular ...
openaire   +3 more sources

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

SINGLE NUCLEOTIDE POLYMORPHISMS APPROACH FOR GENETIC BACKGROUND OF ICR MICE USING MASSARRAY [PDF]

Exploratory Animal and Medical Research
Single nucleotide polymorphisms (SNPs) are an effective method for determining the genetic background of ICR outbred mice in the National Laboratory Animal Center, Mahidol University. We screened 20 SNPs on all autosomes and X chromosome.
Nopparat Phumkumarn, Jarasporn Tangkhabuanbutra, Piyapha Hirunpatrawong, Panya Chariyahpongpun   +3 more
doaj   +1 more source

Abrupt Change in Electrophysiological Properties Begins From Postnatal Day 7 Before Hearing Onset in the Developing Mice Auditory Cortical Layer II/III Neurons [PDF]

Clinical and Experimental Otorhinolaryngology, 2019
Objectives In the developing auditory cortex, maturation of electrophysiological properties and cell types before and after hearing onset has been reported previously. However, the exact timing of firing pattern change has not been reported.
Seung Cheol Ahn
doaj   +1 more source

Scratching Behavior of ICR-Derived Glomerulonephritis (ICGN) Mice

Journal of Veterinary Medical Science, 2010
The ICR-derived glomerulonephritis (ICGN) mouse, an inbred strain with a hereditary nephrotic syndrome, is considered a good animal model of human idiopathic nephrotic syndrome. ICGN mice show proteinuria at a young age, developing hypoalbuminemia, hyperlipidemia, anemia and edema later on.
MIYAMOTO, Yohei, UMEUCHI, Hideo, KUROKAWA, Takahiro, NAKAO, Kaoru, OKANO, Kiyoshi   +4 more
openaire   +3 more sources

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

Comparison of the anesthetic effects of 2,2,2-tribromoethanol on ICR mice derived from three different sources

Laboratory Animal Research, 2018
This study was conducted to compare the anesthetic effects of 2,2,2-tribromoethanol (TBE, Avertin®) in ICR mice obtained from three different sources.
Mi Ree Lee, Hye Rin Suh, Myeong Whan Kim, Joon Young Cho, Hyun Keun Song, Young Suk Jung, Dae Youn Hwang, Kil Soo Kim   +7 more
doaj   +1 more source

Pharmacokinetic Interactions of Flunixin Meglumine and Enrofloxacin in ICR Mice

Experimental Animals, 2007
We examined the pharmacokinetic interactions of enrofloxacin and flunixin in male ICR mice that were subcutaneously (SC) administered with both or either one of the drugs. The experiments were performed on the following three groups: flunixin alone (2 mg/kg, SC), combination of flunixin (2 mg/kg, SC) and enrofloxacin (10 mg/kg, SC), and enrofloxacin ...
OGINO, Tomoe, ARAI, Toshiro
openaire   +3 more sources