Results 91 to 100 of about 2,519 (184)
Dabigatran, the first novel oral anticoagulant (NOAC) with a reversal agent, heralded a paradigm shift in the treatment of nonvalvular atrial fibrillation.
Steven Song +5 more
doaj +1 more source
Direct oral anticoagulants: first airbag
The safety profile of oral anticoagulants (DOACs) was confirmed in the large-scale studies, the increased risk of hemorrhagic events does still exist, which may be caused by the nature of the patient’s concomitant pathology, the resulting injury or the ...
A. N. Sokolova, A. I. Skripka
doaj +1 more source
Idarucizumab is a specific reversal agent that rapidly neutralizes dabigatran’s anticoagulant activity [(1–3)][1]. We investigated restoration of dabigatran anticoagulation 24 h after idarucizumab treatment and the safety and effectiveness of a second idarucizumab treatment.
Stephan, Glund +11 more
openaire +2 more sources
A dabigatran-antidótum, az intravénás idarucizumab első hazai alkalmazása | The first use of iv. idarucizumab for dabigatran reversal in Hungary [PDF]
Absztrakt: Az új típusú, direkt orális antikoagulánsok közül jelenleg egyedül a direkt trombingátló dabigatran rendelkezik hatékony antidótummal.
Zoltán Szántó +15 more
core +1 more source
Practical considerations on anticoagulation reversal: spotlight on the reversal of dabigatran
David Giannandrea,1,2,* Anna Mengoni,3,* Erberto Carluccio,3 Giuseppe Ambrosio31Neurology Departement - Stroke Unit, Gubbio/Gualdo Tadino Hospitals, Perugia, Italy; 2Association “Naso Sano”, Umbria Regional Registry of No-Profit Organization,
Giannandrea D +3 more
doaj
Reducing of cardiovascular risk, morbidity and mortality is considered as one of the main aims of modern cardiology, which should help increase life expectancy.
Yu. A. Karpov
doaj +1 more source
© 2020 Elsevier Ltd. All rights reserved.Introduction: Direct thrombin inhibitor, dabigatran and factor Xa inhibitors, apixaban, edoxaban, and rivaroxaban (DOACs/NOACs), are currently the first-choice drugs in some indications.
Ferreira, Joaquim J +5 more
core +1 more source
Dabigatran, an oral direct thrombin inhibitor, is frequently used in treatment of venous thromboembolism and prevention of stroke in non-valvular atrial fibrillation.
Lene Rosenberg +5 more
core +1 more source

