Anticoagulation with direct thrombin inhibitors was a reasonable periprocedural anticoagulation regimen to reduce periprocedural complications in atrial fibrillation ablation. Abstract Background The guidelines recommend anticoagulation management with uninterrupted warfarin or direct thrombin inhibitors (DTIs) during the atrial fibrillation (AF ...
Yuta Taomoto +27 more
wiley +1 more source
Abstract In the last three decades, ablation of atrial fibrillation (AF) has become an evidence‐based safe and efficacious treatment for managing the most common cardiac arrhythmia. In 2007, the first joint expert consensus document was issued, guiding healthcare professionals involved in catheter or surgical AF ablation. Mounting research evidence and
Stylianos Tzeis +44 more
wiley +1 more source
State of play and future direction with NOACs: An expert consensus. [PDF]
Atrial fibrillation (AF) and venous thromboembolism (VTE) are cardiovascular conditions significant in contemporary practice. In both, the use of anticoagulation with vitamin K antagonists (VKAs) has been traditionally used to prevent adverse events ...
A.J. Camm +135 more
core +5 more sources
CDR L3 Loop Rearrangement Switches Multispecific SPE‐7 IgE Antibody From Hapten to Protein Binding
ABSTRACT The monoclonal IgE antibody SPE‐7 was originally raised against a 2,4‐dinitrophenyl (DNP) target. Through its ability to adopt multiple conformations, the antibody is capable of binding to a diverse range of small haptens and large proteins.
Clarissa A. Seidler, Klaus R. Liedl
wiley +1 more source
Viewpoint Stroke prevention in recent guidelines for the management of patients with atrial fibrillation: An appraisal. [PDF]
Formal guidelines play an important role in disseminating the best available evidence knowledge and are expected to provide simple and practical recommendations for the most optimal management of patients with various conditions.
Camm, AJ +4 more
core +3 more sources
Reversal of the Anticoagulation Effects of Dabigatran Etexilate by Idarucizumab in Three Patients Needing Urgent Surgical Intervention and One Case of Intravenous Thrombolysis in Ischaemic Stroke [PDF]
Objective: To describe the benefits of reversal of the anticoagulation effects of dabigatran etexilate in patients requiring urgent surgery or thrombolysis for ischaemic stroke. Materials and methods: Four patients, treated with dabigatran etexilate and
Brizzi, Marco +2 more
core +1 more source
Outcome of intracerebral hemorrhage associated with different oral anticoagulants [PDF]
Objective: In an international collaborative multicenter pooled analysis, we compared mortality, functional outcome, intracerebral hemorrhage (ICH) volume, and hematoma expansion (HE) between non-vitamin K antagonist oral anticoagulation-related ICH ...
Ambler, Gareth +31 more
core +4 more sources
Intravenous Thrombolysis after Reversal of Dabigatran by Idarucizumab: A Case Report
We describe a 75-year-old female patient with nonvalvular atrial fibrillation who presented with acute ischemic stroke during treatment with dabigatran 2 × 110 mg per day.
Waldemar Kafke +2 more
doaj +1 more source
Anticoagulantes orais diretos, antídotos e possíveis interações [PDF]
Monografia realizada no âmbito da unidade de Estágio Curricular do Mestrado Integrado em Ciências Farmacêuticas, apresentada à Faculdade de Farmácia da Universidade de CoimbraA terapêutica anticoagulante foi, durante um longo período e até há pouco tempo,
Graça, João Pedro Antunes
core
JCS/JHRS 2024 Guideline Focused Update on Management of Cardiac Arrhythmias
Journal of Arrhythmia, Volume 41, Issue 3, June 2025.
Yu‐ki Iwasaki +37 more
wiley +1 more source

