Results 61 to 70 of about 2,468 (182)

Neck‐vein thrombosis during spaceflight

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 24-34, January 2026.
Spaceflight imposes unique environmental challenges, including weightlessness, increased radiation exposure and confinement, which can lead to unexpected health effects. One such example is neck‐vein thrombosis, a condition rarely seen on Earth without predisposing factors such as venous catheters or infections.
Ulrich Limper, Jens Jordan
wiley   +1 more source

Successful thrombolysis with recombinant tissue plasminogen activator after antagonizing dabigatran by idarucizumab: a case report [PDF]

, 2016
Background Effective anticoagulation routinely precludes patients from receiving intravenous thrombolysis with recombinant tissue plasminogen activator to reverse severe symptoms of ischemic stroke.
Pawel Kermer, Gawehn, Annemarie, Kaste, Matthias, Kermer, Pawel, Heuschkel, Christian, Annemarie Gawehn, Ayari, Yassine, Yassine Ayari, Christian Heuschkel, Matthias Kaste   +9 more
core   +2 more sources

Volume replacement strategies do not impair the binding of dabigatran to idarucizumab: Porcine model of hemodilution.

PLoS ONE, 2019
BackgroundIdarucizumab is a humanized Fab fragment that specifically reverses dabigatran anticoagulation. In trauma, volume expanders are used for resuscitation to compensate for blood loss and hemorrhagic shock, but it is unknown whether volume ...
Oliver Grottke, Joanne van Ryn, Christian Zentai, Guanfa Gan, Markus Honickel, Rolf Rossaint, Hugo Ten Cate, Henri M H Spronk   +7 more
doaj   +1 more source

Intracerebral Hemorrhage: Advances, Knowledge Gaps, and Future Directions

MedComm, Volume 6, Issue 11, November 2025.
This review provides a comprehensive synthesis of current research on the epidemiology, pathophysiological mechanisms, imaging characteristics, treatment delays, clinical management strategies, neural repair, and prognostic prediction of intracerebral hemorrhage (ICH).
Tao Liu, Weiwei Jiang, Minzhi Zhang, Shangzhi Xiong, Linan Chen, Xiaoying Chen, Rongcai Jiang   +6 more
wiley   +1 more source

Successful intravenous thrombolysis for ischemic stroke after reversal of dabigatran anticoagulation with idarucizumab: a case report

Journal of Medical Case Reports, 2017
Background Non-vitamin K antagonist oral anticoagulants, including dabigatran, are currently widely used for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation.
Sergio Agosti, Laura Casalino, Enrico Rocci, Gabriele Zaccone, Eugenia Rota   +4 more
doaj   +1 more source

Management of major bleeding in patients treated with direct oral anticoagulants: from experience to standardized protocols

Italian Journal of Medicine, 2020
Evaluation of clinical-laboratory-therapeutic management and related clinical outcomes (thrombotic-hemorrhagic complications) of patients undergoing treatment with direct oral anticoagulants (DOACs) during major bleeding. This is a two-year observational
Sara Mascia, Anna Maria Ferrari, Nicola Macarone Palmieri, Elisa Romagnoli, Chiara Catena, Serena Scarabottini, Francesca Mori, Lucio Brugioni   +7 more
doaj   +1 more source

Non-Vitamin K Oral Anticoagulants Associated Bleeding and Its Antidotes [PDF]

Journal of Stroke, 2018
Oral anticoagulant-associated intracerebral hemorrhage (OAC-ICH) accounts for nearly 20% of all ICH. The number of patients with an indication for oral anticoagulant therapy (OAT) increases with increasing age.
Thorsten Steiner, Martin Köhrmann, Peter D. Schellinger, Georgios Tsivgoulis   +3 more
doaj   +1 more source

Stroke prevention in atrial fibrillation: A narrative review of current evidence and emerging strategies

European Journal of Clinical Investigation, Volume 55, Issue 9, September 2025.
Effective stroke prevention in AF requires a comprehensive holistic approach incorporating appropriate risk stratification, guideline‐adherent anticoagulation and management of underlying cardiovascular conditions and other comorbidities. The ABC pathway, supported by characterisation using the 4S‐AF framework, provides a structured approach to ...
Amir Askarinejad, Deirdre A. Lane, Parham Sadeghipour, Majid Haghjoo, Gregory Y. H. Lip   +4 more
wiley   +1 more source

Left atrial intramural hematoma following right atrial catheter ablation: A rare case involving coronary sinus injury

Journal of Arrhythmia, Volume 41, Issue 4, August 2025.
Left atrial intramural hematoma (LAIH) is an exceedingly rare complication that occurs following catheter ablation in the right atrium. The present case is the first to implicate coronary sinus catheter manipulation—rather than left atrial intervention—as a potential mechanism of LAIH.
Mina Hatsuno, Ken Kobayashi, Kenta Tsutsui, Yuji Watari, Ken Kozuma   +4 more
wiley   +1 more source

Ischemic stroke following reversal of dabigatran with idarucizumab in spontaneous subdural hematoma in cerebral venous thrombosis [PDF]

Spontaneous subdural hematomas (SDH) are an unusual but potentially devastating complication of oral anticoagulation. Emergency management of subdural hematomas following oral anticoagulant therapy consists of reversal of anticoagulation coupled with ...
Acharya, Ullas V., Santhosh, Thanisha, Krishnan, Pramod, Anusha, Donti R., Kalashetty, Mallikarjun   +4 more
core   +1 more source