Results 61 to 70 of about 3,819 (202)

Asia-Pacific working group consensus on non-variceal upper gastrointestinal bleeding: An update 2018 [PDF]

, 2018
Non-variceal upper gastrointestinal bleeding remains an important emergency condition, leading to significant morbidity and mortality. As endoscopic therapy is the 'gold standard' of management, treatment of these patients can be considered in three ...
Bjorkman, D.J. (David J.), Chan, F.K.L. (Francis K.L.), Chiu, P.C.Y. (Philip C.Y.), Goh, K.-L. (Khean-Lee), Gotoda, T. (Takuji), Ho, L.H.Y. (Lawrence H.Y.), Jensen, D.M. (Dennis), Jung, H.-Y. (Hwoon-Young), Kuipers, E.J. (Ernst J.), Lanas, A. (Angel), Lau, J.Y.W. (James), Reddy, N. (N.), Singh, R. (Rajvinder), Sollano, J. (José), Sugano, K. (Kentaro), Sung, J.J.Y. (Joseph), Wu, C.-Y. (Chun-Yin), Wu, K.-C. (Kai-Chun)   +17 more
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Stroke prevention in atrial fibrillation: A narrative review of current evidence and emerging strategies

European Journal of Clinical Investigation, Volume 55, Issue 9, September 2025.
Effective stroke prevention in AF requires a comprehensive holistic approach incorporating appropriate risk stratification, guideline‐adherent anticoagulation and management of underlying cardiovascular conditions and other comorbidities. The ABC pathway, supported by characterisation using the 4S‐AF framework, provides a structured approach to ...
Amir Askarinejad, Deirdre A. Lane, Parham Sadeghipour, Majid Haghjoo, Gregory Y. H. Lip   +4 more
wiley   +1 more source

Left atrial intramural hematoma following right atrial catheter ablation: A rare case involving coronary sinus injury

Journal of Arrhythmia, Volume 41, Issue 4, August 2025.
Left atrial intramural hematoma (LAIH) is an exceedingly rare complication that occurs following catheter ablation in the right atrium. The present case is the first to implicate coronary sinus catheter manipulation—rather than left atrial intervention—as a potential mechanism of LAIH.
Mina Hatsuno, Ken Kobayashi, Kenta Tsutsui, Yuji Watari, Ken Kozuma   +4 more
wiley   +1 more source

The new way of Dabigatran reversal – Idarucizumab

Journal of Education, Health and Sport, 2019
Since last few years a popularity of new oral anticoagulants significantly raised. There are following main direct oral anticoagulants (DOAC) used in therapy: Dabigatran, Rywaroxaban, Apixaban, Endoxaban.
Erwin Ciechański, Krystian Ciechański, Magda Ciechańska, Jarosław Szponar   +3 more
doaj   +3 more sources

Successful use of idarucizumab for the management of intracranial hemorrhage in an elderly woman receiving dabigatran for stroke prevention in atrial fibrillation: A case report

IHJ Cardiovascular Case Reports, 2018
Non-vitamin K antagonist oral anticoagulants are effective for prevention of stroke in atrial fibrillation (AF) but management of emergency situations in some patients receiving these drugs can be challenging.
Manoj Mashru, Mehul S. Shah, Arun B. Shah, Sonesh kalra, Sandeep Bhapkar   +4 more
doaj   +1 more source

Chronic kidney disease and arrhythmias: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. [PDF]

, 2018
Patients with chronic kidney disease (CKD) are predisposed to heart rhythm disorders, including atrial fibrillation (AF)/atrial flutter, supraventricular tachycardias, ventricular arrhythmias, and sudden cardiac death (SCD).
Amann, Kerstin, Banerjee, Debasish, Bansal, Nisha, Blankestijn, Peter J, Boriani, Giuseppe, Bunch, Jared, Carrero, Juan-Jesus, Chan, Christopher T, Charytan, David M, Cheung, Michael, Clase, Catherine M, Conen, David, Conference Participants, Deo, Rajat, Friedman, Allon N, Genovesi, Simonetta, Herzog, Charles A, Holden, Rachel M, House, Andrew A, Jadoul, Michel, Jardine, Alan G, Johnson, David W, Jun, Min, Kasner, Scott E, Labriola, Laura, Mark, Patrick B, McCullough, Peter A, Nolin, Thomas D, Passman, Rod S, Pecoits-Filho, Roberto, Potpara, Tatjana S, Pun, Patrick H, Reinecke, Holger, Ribeiro, Antonio L P, Rossignol, Patrick, Shen, Jenny I, Shroff, Gautam R, Sood, Manish M, Tsukamoto, Yusuke, Turakhia, Mintu P, Wang, Angela Yee-Moon, Wanner, Christoph, Weir, Matthew R, Wetmore, James B, Wheeler, David C, Winkelmayer, Wolfgang C, Wranicz, Jerzy K, Yamasaki, Hiro, Zareba, Wojciech   +48 more
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Intravenous Thrombolysis in Patients Taking Direct Oral Anticoagulation Treatment Before Stroke Onset: Results from the Safe Implementations of Treatments in Stroke International Stroke Registry

Annals of Neurology, Volume 97, Issue 6, Page 1205-1214, June 2025.
Objectives Intravenous thrombolysis (IVT) is contraindicated for acute ischemic stroke (AIS) patients taking direct oral anticoagulants (DOACs) within 48 hours before index stroke. Limited data exist on off‐label use of IVT for these patients. We compared the safety and outcomes of IVT in AIS patients with DOAC treatment and patients with no OAC before
Marius Matusevicius, Malin Säflund, Maurizio Balestrino, Manuel Cappellari, Delfina Ferrandi, Abdoreza Ghoreishi, André Peeters, Viiu‐Marika Rand, Manuela De Michele, Aleksandras Vilionskis, Andrea Zini, Niaz Ahmed   +11 more
wiley   +1 more source

Volume replacement strategies do not impair the binding of dabigatran to idarucizumab: Porcine model of hemodilution.

PLoS ONE, 2019
BackgroundIdarucizumab is a humanized Fab fragment that specifically reverses dabigatran anticoagulation. In trauma, volume expanders are used for resuscitation to compensate for blood loss and hemorrhagic shock, but it is unknown whether volume ...
Oliver Grottke, Joanne van Ryn, Christian Zentai, Guanfa Gan, Markus Honickel, Rolf Rossaint, Hugo Ten Cate, Henri M H Spronk   +7 more
doaj   +1 more source

The toxicokinetic profile of Dex40-GTMAC3 : a novel polysaccharide candidate for reversal of unfractionated heparin [PDF]

, 2016
Though protamine sulfate is the only approved antidote of unfractionated heparin (UFH), yet may produce life threatening side effects such as systemic hypotension, catastrophic pulmonary vasoconstriction or allergic reactions.
Błażejczyk, Agnieszka, Kamiński, Kamil, Kasacka, Irena, Kałaska, Bartłomiej, Lewandowska, Alicja, Mogielnicki, Andrzej, Nowakowska, Maria, Pawlak, Dariusz, Sokolowska, Emilia, Szczubiałka, Krzysztof, Wietrzyk, Joanna   +10 more
core   +2 more sources

Dabigatrán fronte acenocumarol ou warfarina en pacientes con fibrilación auricular [PDF]

, 2018
[Resumo] Introdución: A fibrilación auricular non valvular (FANV) é a arritmia máis frecuente e o ictus a súa principal complicación. Nos pacientes con alto risco de embolización, a terapia anticoagulante demostrou ser altamente eficaz. Os antagonistas
García Costa, Noelia
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