Results 111 to 120 of about 7,459,988 (350)
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Foram utilizadas 76 fêmeas suínas lactantes de médio potencial genético com peso inicial de 207,0 ± 32,0 kg e ordem de parto de 3,53 ± 2,11, para avaliar níveis de treonina digestível na fase de lactação.
Charles Kiefer +5 more
doaj +1 more source
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Evaluation of agro-industrial by-products as protein sources for duck production in the Mekong Delta of Vietnam [PDF]
This thesis is based on four studies to determine the nutritive value and ileal and total tract amino acid digestibility of agro-industrial by-products, and the effects of inclusion of these by-products in diets on the biological performance of growing ...
Nguyen, Thi Kim Dong
core
The objective of the present study was to investigate crude protein reduction and the methionine+cystine and threonine to lysine ratios in diets for reversed Nile tilapia fingerlings (Oreochromis niloticus), Thai strain.
Moisés Quadros +5 more
doaj +1 more source
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Dietary protein levels for juvenile matrinxã (Brycon amazonicus) reared in biofloc and clear water systems [PDF]
This study evaluated the potential for rearing matrinxã (Brycon amazonicus) with different crude protein (CP) levels and using production performance, water quality, and animal welfare as indicators.
Rafaelle Borges Cunha +5 more
doaj +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source

