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Idiopathic Membranous Nephropathy in Two Brothers

Nephron, 2008
Idiopathic membranous nephropathy has been reported rarely to develop in genetic association with certain HLA antigens. This paper describes two male siblings presenting with nephrotic syndrome with histologically proven membranous nephropathy. The younger brother maintained a normal renal function with slight proteinuria during the 3 years of follow ...
K, Sato   +6 more
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Idiopathic membranous nephropathy in identical twins

American Journal of Kidney Diseases, 1997
Familial idiopathic membranous nephropathy is rarely reported, despite the striking immunogenetic association of the disease with certain HLA antigens. This report describes a pair of identical male twins who contemporaneously developed idiopathic membranous nephropathy. HLA typing was carried out in the twins and in almost all members of their family.
A, Guella, M, Akhtar, P, Ronco
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Prognosis of untreated patients with idiopathic membranous nephropathy

Pediatric Nephrology, 1993
Defining the most appropriate treatment for patients with idiopathic membranous nephropathy is a matter of controversy. The course of the disorder is often benign, and the immunosuppressive regimens used in some patients have uncertain benefits and substantial risks.
A, Schieppati   +6 more
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Therapy of Idiopathic Membranous Nephropathy

Clinical Immunotherapeutics, 1996
Idiopathic membranous nephropathy (IMN) is an autoimmune disease without specific aetiology and defined by proteinuria that is often in the nephrotic range and granular deposits of IgG among the glomeruli. It is the causative renal disease in about 3% of patients requiring dialysis.
Guy Rostoker, Bertrand Weil
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Idiopathic membranous nephropathy

The Lancet, 1993
G. Remuzzi, T. Bertani, A. Schieppati
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[Treatment of idiopathic membranous nephropathy].

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2005
Corticosteroids and cytotoxic agents have been largely used in idiopathic membranous nephropathy (MN). A meta-analysis of controlled studies with corticosteroids did not demonstrate any benefit in using these agents on disease outcome. On the contrary, some controlled trials reported that cytotoxic agents can significantly reduce proteinuria.
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