Results 201 to 210 of about 243,754 (245)

Treatment of Idiopathic Membranous Nephropathy

Nature Reviews Nephrology, 2013
Immunosuppressive treatment of patients with idiopathic membranous nephropathy (iMN) is heavily debated. The controversy is mainly related to the toxicity of the therapy and the variable natural course of the disease-spontaneous remission occurs in 40-50% of patients.
Jack F M Wetzels, Julia M Hofstra
exaly   +3 more sources

Oxidative stress and inflammation are mediated via aryl hydrocarbon receptor signalling in idiopathic membranous nephropathy.

Free Radical Biology & Medicine, 2023
Membranous nephropathy (MN) patients are diagnosed by the presence of phospholipase A2 receptor (PLA2R) before they progress to renal failure. However, the subepithelium-like immunocomplex deposit-mediated downstream molecular pathways are poorly ...
Yan-Ni Wang, Hua Miao, Xiao-Yong Yu, Yan Guo, Wei Su, Fei Liu, Gang Cao, Ying-Liang Zhao   +7 more
semanticscholar   +1 more source

Altered Intestinal Microbial Flora and Metabolism in Patients with Idiopathic Membranous Nephropathy

American Journal of Nephrology, 2023
Introduction: Dysbiosis of the intestinal microbiome and related metabolites have been observed in chronic kidney disease, yet their roles in idiopathic membranous nephropathy (IMN) are poorly understood. Methods: In this study, we describe the variation
Xiaohu Shi, Zhaojun Li, Weifeng Lin, Wenying Shi, Rong-Rong Hu, Gang Chen, Xue-Mei Li, Xue-Wang Li, Sen Zhang   +8 more
semanticscholar   +1 more source

Machine learning model to estimate probability of remission in patients with idiopathic membranous nephropathy.

International Immunopharmacology, 2023
BACKGROUND Idiopathic membranous nephropathy (IMN) is a type of nephrotic syndrome and the leading cause of chronic kidney disease. As far as we know, no predictive model for assessing the prognosis of IMN is currently available.
Li-Jin Duo, Lei Chen, Yongdi Zuo, Jiu-Ling Guo, Manrong He, Hong-Sen Zhao, Ying-Xi Kang, Wan-Xin Tang   +7 more
semanticscholar   +1 more source

Idiopathic Membranous Nephropathy

Lancet, The, 1993
Giuseppe Remuzzi, Tullio Bertani, A Schieppati   +2 more
exaly   +2 more sources

Treatment of Idiopathic Membranous Nephropathy

New England Journal of Medicine, 1976
In a retrospective study of the effect of treatment in biopsy-proved idiopathic membranous nephropathy, 91 adults and 12 children were followed for periods up to 29 years after clinical onset (mean, 6.5 years). Forty-four were treated with corticosteroids, 15 with corticosteroids and immunosuppressants; 44 had no treatment and served as a control group.
T, Ehrenreich, J G, Porush, J, Churg, L, Garfinkel, S, Glabman, M H, Goldstein, E, Grishman, S L, Yunis   +7 more
openaire   +2 more sources

Prediction in Idiopathic Membranous Nephropathy [PDF]

Kidney International, 1999
Results of the prognosis of idiopathic membranous nephropathy are conflictive and prevent an effective risk stratification. These conflicts are explained in part by insufficient consideration of methodological principles for prognostic research.
Marx, Brigitte E., Marx, Martin
exaly   +3 more sources

Management of idiopathic membranous nephropathy

Expert Opinion on Pharmacotherapy, 2010
Idiopathic membranous nephropathy (IMN) can have a variable natural course. Treatments able to induce remission can improve the long-term prognosis. However, the optimal therapy for IMN remains controversial.We reviewed the historical and current literature from 1979 to 2010 regarding the natural course of IMN and the possible treatments giving special
Claudio, Ponticelli, Patrizia, Passerini
openaire   +2 more sources

Idiopathic membranous nephropathy in the elderly

Nephrology Dialysis Transplantation, 1993
Abstract In this retrospective non-randomized study we reviewed the outcome for 41 patients with membranous nephropathy older than 65 years at onset and followed for at least 1 year. Twelve of the patients never received any specific treatment (group A), 15 were treated with a 6-month course of methylpredniso-lone alternated to ...
P, Passerini, G, Como, E, Viganò, P, Melis, C, Pozzi, P, Altieri, C, Ponticelli   +6 more
openaire   +2 more sources

Elevated circulating CD19+CD24hiCD38hi B cells display pro-inflammatory phenotype in idiopathic membranous nephropathy.

Immunology Letters, 2023
CD19+CD24hiCD38hi regulatory B cells exert immunosuppressive functions by producing IL-10, but their role in idiopathic membranous nephropathy (IMN) remains elusive.
Bishun Deng, Li Deng, Miao Liu, Ziling Zhao, Hui Huang, Xiaoxin Tu, En-yu Liang, R. Tian, Xiaowan Wang, Rong-Rong Wang, Hai-Biao Lin, Yongyi Yu, A. Peng, Peng Xu, K. Bao, Min He   +15 more
semanticscholar   +1 more source