Results 121 to 130 of about 182,666 (399)
Imaging diagnosis-computed tomography of traction bronchiectasis secondary to pulmonary fibrosis in a Patterdale Terrier [PDF]
, 2017 An 8-year-old, Patterdale terrier was referred for evaluation of tachypnoea, exercise intolerance, and weight loss. Computed tomographic images showed pneumomediastinum, diffuse pulmonary ground glass opacity, and marked dilatation of peripheral bronchi,
Fitzgerald, E +2 more
core +1 more source
bioRxiv, 2019 We provide a single cell atlas of Idiopathic Pulmonary Fibrosis (IPF), a fatal interstitial lung disease, focusing on resident lung cell populations. By profiling 312,928 cells from 32 IPF, 29 healthy control and 18 chronic obstructive pulmonary disease (
T. Adams +17 more
semanticscholar +1 more source
Gender Differences in Survival in Idiopathic Pulmonary Fibrosis and Following Lung Transplant [PDF]
, 2008 Idiopathic Pulmonary Fibrosis (IPF) is a chronic and progressive form of interstitial lung disease characterized by inflammation and abnormal tissue repair ultimately leading to decreased pulmonary function and death.
Creel, Michael Eric
core
Autophagy in Idiopathic Pulmonary Fibrosis
PLoS ONE, 2012 Autophagy is a basic cellular homeostatic process important to cell fate decisions under conditions of stress. Dysregulation of autophagy impacts numerous human diseases including cancer and chronic obstructive lung disease. This study investigates the role of autophagy in idiopathic pulmonary fibrosis.Human lung tissues from patients with IPF were ...
Avignat Patel +8 more
openaire +5 more sources
Metabolic alterations in human pulmonary artery smooth muscle cells treated with PDGF‐BB
Animal Models and Experimental Medicine, EarlyView.Metabolic abnormalities are considered to play a key regulatory role in vascular remodeling of pulmonary arterial hypertension. We analyzed the metabolome in the culture supernatants of human pulmonary artery smooth muscle cells (PASMC) during the malignant proliferation phenotype transition via a targeted metabolomics method. Significant and extensive
Meng‐Jie Zhang +9 more
wiley +1 more source
Heterologous matrix metalloproteinase gene promoter activity allows In Vivo real-time imaging of Bleomycin-induced Lung fibrosis in transiently transgenized mice [PDF]
, 2017 Idiopathic pulmonary fibrosis is a very common interstitial lung disease derived from chronic inflammatory insults, characterized by massive scar tissue deposition that causes the progressive loss of lung function and subsequent death for respiratory ...
Donofrio, Gaetano +8 more
core +1 more source
Idiopathic pulmonary fibrosis: pathogenesis and management
Respiratory Research, 2018 BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease characterized by the aberrant accumulation of fibrotic tissue in the lungs parenchyma, associated with significant morbidity and poor prognosis.
G. Sgalla +5 more
semanticscholar +1 more source
Animal Models and Experimental Medicine, EarlyView.Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai +8 more
wiley +1 more source
Natural products targeting tumour angiogenesis
British Journal of Pharmacology, EarlyView., 2023 Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu +2 more
wiley +1 more source
SNAI transcription factors mediate epithelial--mesenchymal transition in lung fibrosis [PDF]
, 2009 Background: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterised by accumulation of activated (myo)fibroblasts and excessive extracellular matrix deposition.
Eickelberg, O. +7 more
core +1 more source