Results 211 to 220 of about 204,699 (375)

Impaired Right, Left, or Biventricular Function and Resting Oxygen Saturation Are Associated With Mortality in Eisenmenger Syndrome: A Clinical and Cardiovascular Magnetic Resonance Study. [PDF]

open access: yes, 2015
Babu-Narayan, SV   +9 more
core   +1 more source

Single lung transplantation from a brain-dead donor for a patient with idiopathic pulmonary fibrosis [PDF]

open access: bronze, 2001
Shinichiro Miyoshi   +5 more
openalex   +1 more source

Resolution of inflammation in pulmonary arterial hypertension, the influence of sex—An IUPHAR immunopharmacology committee review

open access: yesBritish Journal of Pharmacology, EarlyView.
Pulmonary arterial hypertension (PAH) is a progressive and life‐threatening disease with limited treatment options. Sex differences are apparent in PAH, specifically in the pathophysiology, prognoses and pharmacological responses of patients. Inflammation and its resolution, which often differ between sexes, are dysregulated in chronic inflammatory ...
Chloe Landy   +5 more
wiley   +1 more source

Mechanopharmacology of cellular microenvironment stiffness: Therapeutic strategies for age‐related diseases

open access: yesBritish Journal of Pharmacology, EarlyView.
Ageing brings about various biochemical, structural and mechanical alterations within tissues, profoundly impacting cellular behaviour and function. One of the hallmark changes observed with ageing is an increase in cellular microenvironment stiffness, a biomechanical property influenced by intrinsic factors within the cell and extrinsic factors from ...
Wang HaiYang   +3 more
wiley   +1 more source

Beyond Carrier Status: CFTR Heterozygosity as an Overlooked Clinical Risk Factor for Pancreatitis

open access: yesClinical Genetics, EarlyView.
CFTR carrier status detected via prenatal screening is associated with increased pancreatitis risk in women, but clinical recognition remains low. Integrating carrier results into electronic health records may enhance personalized care and aid in early diagnosis. ABSTRACT This study assessed the effect of CFTR pathogenic variant status, detected during
Lucas D. Richter   +3 more
wiley   +1 more source

Super‐Enhancer Target Gene CBP/p300‐Interacting Transactivator With Glu/Asp‐Rich C‐Terminal Domain, 2 Cooperates With Transcription Factor Forkhead Box J3 to Inhibit Pulmonary Vascular Remodeling

open access: yesCell Proliferation, EarlyView.
During hypoxia, the transcriptional effect of super‐enhancer in promoting CBP/p300‐interacting transactivator with Glu/Asp‐rich C‐terminal domain, 2 reduced, eventually leading to the thickening of the smooth muscle layer of the pulmonary artery.
Songyue Li   +11 more
wiley   +1 more source

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