Results 211 to 220 of about 195,645 (350)

Beyond Carrier Status: CFTR Heterozygosity as an Overlooked Clinical Risk Factor for Pancreatitis

open access: yesClinical Genetics, EarlyView.
CFTR carrier status detected via prenatal screening is associated with increased pancreatitis risk in women, but clinical recognition remains low. Integrating carrier results into electronic health records may enhance personalized care and aid in early diagnosis. ABSTRACT This study assessed the effect of CFTR pathogenic variant status, detected during
Lucas D. Richter   +3 more
wiley   +1 more source

Upregulation of Fas-signalling molecules in lung epithelial cells from patients with idiopathic pulmonary fibrosis [PDF]

open access: bronze, 2001
Takuya Maeyama   +9 more
openalex   +1 more source

Super‐Enhancer Target Gene CBP/p300‐Interacting Transactivator With Glu/Asp‐Rich C‐Terminal Domain, 2 Cooperates With Transcription Factor Forkhead Box J3 to Inhibit Pulmonary Vascular Remodeling

open access: yesCell Proliferation, EarlyView.
During hypoxia, the transcriptional effect of super‐enhancer in promoting CBP/p300‐interacting transactivator with Glu/Asp‐rich C‐terminal domain, 2 reduced, eventually leading to the thickening of the smooth muscle layer of the pulmonary artery.
Songyue Li   +11 more
wiley   +1 more source

Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina   +8 more
wiley   +1 more source

Familial idiopathic pulmonary fibrosis in a young female

open access: yesRespiratory Medicine Case Reports, 2018
Idiopathic pulmonary fibrosis is a chronic interstitial lung disease of unknown cause. In the past years there have been observations of clustering of pulmonary fibrosis in families, indicating the disease can be inherited.
Sajitha S. Sritharan   +4 more
doaj  

d‐amino acids: new functional insights

open access: yesThe FEBS Journal, EarlyView.
This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni   +5 more
wiley   +1 more source

Inhaled beclomethasone/formoterol in idiopathic pulmonary fibrosis: A randomised controlled exploratory study [PDF]

open access: yes, 2017
Brindle, Kayleigh   +5 more
core   +2 more sources

The Landscape of SPP1+ Macrophages Across Tissues and Diseases: A Comprehensive Review

open access: yesImmunology, EarlyView.
SPP1+ macrophages represent a conserved, disease‐associated population present across cancerous and non‐cancerous conditions, involved in immunosuppression, fibrosis, lipid metabolism, phagocytosis, and other cellular processes. This review highlights their shared molecular programmes across tissues, their interactions with stromal and immune cells ...
Alessandro Palma
wiley   +1 more source

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