Results 31 to 40 of about 304,612 (248)

Ekspresi IFN-γ dan IL-4 CD4+T Limfosit pada Tuberkulosis Kontak terhadap Antigen 38 Kda Mycobacterium tuberculosis

Jurnal Kedokteran Brawijaya, 2015
Mengendalikan epidemi tuberkulosis pada anak adalah prioritas kesehatan global. Efikasi vaksin Bacillus of Calmette and Guerin (BCG) sangat bervariasi sehingga memerlukan pengembangan vaksin baru. Antigen rekombinan 38 Kda Mycobacterium tuberculosis sebagai kandidat vaksin harus melalui uji imunogenitas.
Iin Trilistiyanti Nugrahani, HMS Chandra Kusuma, Tri Yudani Mardining Raras, Maimun Zulhaidah Arthamin, Tri Wahju Astuti, Francisca Tanoerahardjo   +5 more
openaire   +2 more sources

In vitro Production of IL-6 and IFN-γ is Influenced by Dietary Variables and Predicts Upper Respiratory Tract Infection Incidence and Severity Respectively in Young Adults [PDF]

Frontiers in Immunology, 2015
Assessment of immune responses in healthy adults following dietary or lifestyle interventions is challenging due to significant inter-individual variability. Thus, gaining a better understanding of host factors that contribute to the heterogeneity in immunity is necessary.
Meng, Huicui, Lee, Yujin, Ba, Zhaoyong, Fleming, Jennifer A., Furumoto, Emily J., Roberts, Robert F., Kris-Etherton, Penny M., Rogers, Connie J.   +7 more
openaire   +3 more sources

Familial hemophagocytic lymphohistiocytosis hepatitis is mediated by IFN-γ in a predominantly hepatic-intrinsic manner

PLoS ONE, 2022
Interferon gamma (IFN-γ) is the main cytokine driving organ dysfunction in Familial Hemophagocytic Lymphohistiocytosis (FHL). Blockade of IFN-γ pathway ameliorates FHL hepatitis, both in animal models and in humans with FHL.
Tamir Diamond, Thomas N. Burn, Mailyn A. Nishiguchi, Danielle Minichino, Julie Chase, Niansheng Chu, Portia A. Kreiger, Edward M. Behrens   +7 more
doaj   +3 more sources

Patients with Allergic Rhinitis Show an Allergen-Specific Interferon-Gamma Defect

European Journal of Inflammation, 2008
Allergic rhinitis (AR) is characterized by Th2 polarized immune response. Consequently, allergic patients have a defect in IFN-γ production. So far, however, all the experimental studies have investigated only the IFN-γ production induced by the causal ...
D. Fenoglio, A. Ferrera, F. Ferrera, M.P. Sormani, M. di Gioacchino, G. Ciprandi   +5 more
doaj   +1 more source

Differential Cytotoxicity but Augmented IFN-γ Secretion by NK Cells after Interaction with Monocytes from Humans, and Those from Wild Type and Myeloid-Specific COX-2 Knockout Mice [PDF]

Frontiers in Immunology, 2015
The list of genes, which augment NK cell function when knocked out in neighboring cells is increasing, and may point to the fundamental function of NK cells targeting cells with diminished capability to differentiate optimally since NK cells are able to target less differentiated cells, and aid in their differentiation.
Han-Ching eTseng, Aida eArasteh, Kawaljit eKaur, Anna eKozlowska, Anna eKozlowska, Paytsar eTopchyan, Anahid eJewett, Anahid eJewett   +7 more
openaire   +3 more sources

Neutralizing Activity of Anti-interferon-γ Autoantibodies in Adult-Onset Immunodeficiency Is Associated With Their Binding Domains

Frontiers in Immunology, 2019
Adult-onset immunodeficiency (AOID) with anti-interferon-γ (IFN-γ) autoantibodies (autoAbs) is an emerging immunodeficiency syndrome in Asian countries. The presence of neutralizing anti-IFN-γ autoAbs are significantly associated with severe disseminated
Umpa Yasamut, Umpa Yasamut, Weeraya Thongkum, Weeraya Thongkum, Weeraya Thongkum, Sutpirat Moonmuang, Sutpirat Moonmuang, Sutpirat Moonmuang, Supachai Sakkhachornphop, Romanee Chaiwarith, Jutarat Praparattanapan, Jiraprapa Wipasa, Kriangkrai Chawansuntati, Khuanchai Supparatpinyo, Khuanchai Supparatpinyo, Ethan Lai, Chatchai Tayapiwatana, Chatchai Tayapiwatana   +17 more
doaj   +1 more source

Mechanism underlying defective interferon gamma-induced IDO expression in non-obese diabetic mouse fibroblasts. [PDF]

PLoS ONE, 2012
Indoleamine 2,3-dioxygenase (IDO) can locally suppress T cell-mediated immune responses. It has been shown that defective self-tolerance in early prediabetic female non-obese diabetic (NOD) mice can be attributed to the impaired interferon-gamma (IFN-γ)-
Azadeh Hosseini-Tabatabaei, Reza Baradar Jalili, Yunyuan Li, Ruhangiz T Kilani, Alireza Moeen Rezakhanlou, Aziz Ghahary   +5 more
doaj   +1 more source

PERCENTAGE OF CD3+ T LYMPHOCYTES EXPRESSING IFN-γ AFTER CFP-10 STIMULATION (Persentase Limfosit T-CD3+ yang Mengekspresikan Interferon Gamma Setelah Stimulasi Antigen CFP-10)

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2018
Tuberkulosis (TB) merupakan penyakit infeksi menular, disebabkan oleh Mycobacterium tuberculosis. Respons imun adaptif yangdiperantarai oleh limfosit T berperan sangat penting dalam menyingkirkan bakteri intraseluler. Hasilan sitokin IFN-γ merupakanmekanisme efektor utama dari limfosit T.
Yulia Nadar Indrasari, Betty Agustina Tambunan, Jusak Nugraha, Fransiska Sri Oetami   +3 more
openaire   +2 more sources

Effects of oral desloratadine citrate disodium combined with physiological seawater nasal irrigation on IgE levels, IL-4, IL-6, IL-13 and IFN-γ expression and treatment of intermittent allergic rhinitis

Cellular and Molecular Biology, 2020
This experiment was performed to explore the effect of oral desloratadine citrate disodium combined with physiological seawater nasal irrigation in the treatment of intermittent allergic rhinitis and its effect on serum inflammatory factors and peripheral blood Th1 and Th2.
Yuanyuan, Zhang, Wei, Li
openaire   +3 more sources

The Different Effects of IFN-β and IFN-γ on the Tumor-Suppressive Activity of Human Amniotic Fluid-Derived Mesenchymal Stem Cells

Stem Cells International, 2019
Current studies have shown that type I or II interferon-modified mesenchymal stem cells have great potential for the application of tumor-targeted therapy, but the underlying mechanism remains largely elusive.
Jingchun Du, Anqi Liu, Rui Zhu, Chengbo Zhou, Heng Su, Guie Xie, Yingshan Deng, Xia Xu   +7 more
doaj   +1 more source