Results 21 to 30 of about 304,612 (248)
Mycobacterium bovisbacillus Calmette-Guérin infection promotes SOCS induction and inhibits IFN-γ-stimulated JAK/STAT signaling in J774 macrophages [PDF]
FEMS Immunology & Medical Microbiology, 2003 The resurgence in mycobacterial infection worldwide has led to renewed attention to the pathogenesis of Mycobacterium species. Although interferon-gamma (IFN-gamma) is a principal mediator of macrophage activation, macrophages infected with Mycobacterium are poor in response at the cytokine.
Kenichi, Imai +2 more
openaire +2 more sources
Scientific Reports, 2021 Mesenchymal stem cells (MSCs) administered for therapeutic purposes can be activated by interferon-γ (IFN-γ) secreted from natural killer cells in injured tissues and exert anti-inflammatory effects.
Ryo Kanai +11 more
doaj +1 more source
Frontiers in Microbiology, 2022 ObjectivesWe analyzed the results of the QuantiFERON Glod Plus assay (QFT) and cytokine patterns associated with active tuberculosis (ATB) among patients with positive QFT.MethodsA total of 195 patients are QFT-positive, among which 24 had an ATB and 171
Séverine Carrère-Kremer +8 more
doaj +1 more source
Jurnal Kedokteran Brawijaya, 2015 Probiotik dan Nigella sativa memiliki efek imunomodulator dan telah banyak banyak dikaji penggunaannya dalam kombinasi dengan imunoterapi asma. Imunoterapi dapat merubah perjalanan alamiah asma yang melibatkan perubahan respon imun Th2 menjadi Th1 dengan peningkatan IFN-γ.
Debby Christinne Sumantri +4 more
openaire +2 more sources
Histamine receptor H1 is required for TCR-mediated p38 MAPK activation and optimal IFN-γ production in mice [PDF]
Journal of Clinical Investigation, 2007 Histamine receptor H1 (H1R) is a susceptibility gene in both experimental autoimmune encephalomyelitis (EAE) and experimental autoimmune orchitis (EAO), 2 classical T cell-mediated models of organ-specific autoimmune disease. Here we showed that expression of H1R in naive CD4+ T cells was required for maximal IFN-gamma production but was dispensable ...
Noubade, R +6 more
openaire +3 more sources
Role of IFN-γ and LPS on neuron/glial co-cultures infected by Neospora caninum [PDF]
Frontiers in Cellular Neuroscience, 2014 Neospora caninum causes cattle abortion and neurological symptoms in dogs. Although infection is usually asymptomatic, classical neurological symptoms of neosporosis may be associated with encephalitis. This parasite can grow in brain endothelial cells without markedly damages, but it can modulate the cellular environment to promote its survival in the
De Jesus, Erica Etelvina Viana +7 more
openaire +3 more sources
Frontiers in Immunology, 2015 The role of interferon-γ (IFN-γ) in multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE) has remained as an enigmatic paradox for more than 30 years.
Gabriel eArellano +4 more
doaj +1 more source
IFN-γ and TNF-α Synergize to Inhibit CTGF Expression in Human Lung Endothelial Cells [PDF]
PLoS ONE, 2012 Connective tissue growth factor (CTGF/CCN2) is an angiogenetic and profibrotic factor, acting downstream of TGF-β, involved in both airway- and vascular remodeling. While the T-helper 1 (Th1) cytokine interferon-gamma (IFN-γ) is well characterized as immune-modulatory and anti-fibrotic cytokine, the role of IFN-γ in lung endothelial cells (LEC) is ...
Laug, Roderich +6 more
openaire +5 more sources
Frontiers in Immunology, 2019 Severe fever with thrombocytopenia syndrome (SFTS) is a life-threatening infectious disease caused by a novel phlebovirus, SFTS virus (SFTSV). Currently, there is no vaccine or antiviral available and the viral pathogenesis remains largely unknown.
Yun-Jia Ning +12 more
doaj +1 more source
BMC Infectious Diseases, 2022 Background Active tuberculosis (ATB) originates from primary Mycobacterium tuberculosis (MTB) infection or reactivation of latent tuberculosis. Besides bacteriological examination, MTB-reactive immunocytes detection can be an alternative testing for ...
Yong Fang +8 more
doaj +1 more source