Results 1 to 10 of about 236,041 (119)
Interferon‐γ–Responsive Microglia‐Derived Extracellular Vesicles Inhibited Neurogenesis After Stroke via MicroRNA‐199a‐5p/SIRT1 Axis [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Previous studies have reported the presence of interferon‐responsive microglia in the brain after central nervous system injury. However, their roles and the underlying mechanisms in neurological function recovery remain poorly understood ...
Tongtong Xu +17 more
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INF-γ Enhances Nox2 Activity by Upregulating phox Proteins When Applied to Differentiating PLB-985 Cells but Does Not Induce Nox2 Activity by Itself. [PDF]
PLoS ONE, 2015 The cytokine and drug interferon-γ enhances superoxide anion production by the antimicrobicidal Nox2 enzyme of neutrophils. Because mature neutrophils have a short lifespan, we hypothesized that the effects of interferon-γ on these cells might be ...
Michael A Ellison +5 more
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Interferon-γ suppresses intestinal epithelial aquaporin-1 expression via Janus kinase and STAT3 activation. [PDF]
PLoS ONE, 2015 Inflammatory bowel diseases are associated with dysregulated electrolyte and water transport and resultant diarrhea. Aquaporins are transmembrane proteins that function as water channels in intestinal epithelial cells.
Michael S Dicay +6 more
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Сибирский онкологический журнал, 2023 Purpose of the study: to analyze published data on the mechanisms of action of interferon gamma (IFN-γ) in tumor growth and to evaluate the possibility of its use in the treatment of solid tumors. Material and Methods.
A. L. Ilyushin +4 more
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Журнал инфектологии, 2023 Goal. Characteristics of innate, cellular and adaptive immunity in patients of the older age group with COVID19.Materials and methods. Blood leukocytes were induced by Newcastle disease virus (α-interferon), phytohemagglutinin (γ-interferon), SARS CoV 2:
O. N. Scheglovitova +10 more
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Low Interferon-γ Levels in Cord and Peripheral Blood of Pregnant Women Infected with SARS-CoV-2
Microorganisms, 2023 COVID-19 is characterized by the immune system’s overreaction resulting in a ‘cytokine storm’, consisting in a massive release of cytokine into the bloodstream, leading to local and systemic inflammatory response.
Michele Cennamo +11 more
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Zhongliu Fangzhi Yanjiu, 2022 Objective To investigate the effect of IFN-γ on the proliferation and migration of esophageal squamous cell carcinoma cell line Eca9706 and related mechanism. Methods Cells were cultured in vitro and treated with interferon-γ.
CHEN Huicong +7 more
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Molecular Pain, 2020 Recent studies have demonstrated an important role of the pro-inflammatory cytokine interferon-γ in neuropathic pain. Interferon-γ is upregulated in the lumbar spinal cord of nerve-injured rodents and intrathecal injection of interferon-γ has been shown ...
Gerda Reischer +2 more
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LEVELS’ INFLUENCE OF IFN-γ AND IL-10 IN CHILDREN WITH EPILEPTICUS STATUS
Malang Neurology Journal, 2018 Background. Seizures are a common clinical manifestation in the emergency room. Nearly 5% of children aged under 16 years. Seizures are important as a sign of neurological disorders.
Irfan Agus Salim +2 more
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The Scientific World Journal, 2012 Tumour necrosis factor-α, interferon-γ and interleukin-4 are critical cytokines in regulating the immune responses against infections and tumours.
Wenyi Gu +3 more
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