Results 21 to 30 of about 236,190 (268)
Mediators of Inflammation, 1994 Recombinant rat interferon γ stimulated the contractility of isolated rat ileum at doses of 4–12 units/ml. Muscarinic cholinoceptors were involved, as treatment of the tissue with atropine prevented the contractile response of the ileum.
Enri S. Borda +3 more
doaj +1 more source
Acta Medica, 2009 Background: Francisella tularensis, a causative agent of human tularemia, displaying the ability to proliferate inside the human cells. Aims: To evaluate the growth potential of F.
Monika Holická +4 more
doaj +1 more source
KORELASI ANTARA KADAR INTERFERON-γ PLASMA DENGAN JUMLAH VIRAL LOAD DI PENDERITA HIV
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2018 The incidence of HIV is increasing in Indonesia and Asia as well, Indonesia is considered as the most rapid. One of the diagnostic toolsfor diagnosing HIV is by viral load. Lymphocyte T-CD8+ secreted IFN-γ will inhibit replication of HIV virus through the induction of antiviralprotein and the host immune response, which kills infected cells.
Indita, Hermi +2 more
openaire +2 more sources
Monaldi Archives for Chest DiseaseTraditionally, tuberculosis (TB) has been viewed as having two distinct manifestations, known as TB infection (TBI) and TB disease. The spectrum, however, has recently been expanded to include the elimination of TBI with the help of innate and/or ...
Malay Sarkar, Jasmine Sarkar
doaj +1 more source
New Microbes and New Infections, 2019 This study describes a patient who experienced hepatobiliary Mycobacterium avium infection associated with neutralizing anti–interferon gamma (IFN-γ) autoantibodies during treatment for disseminated M. avium disease. Hepatobiliary M.
H. Namkoong +10 more
doaj +1 more source
Galen Medical Journal, 2021 Background: Gliomas possess low immunogenicity, which is an inevitable hinder in front of cancer immunotherapy. Different interferons (IFNs) may proceed apoptosis instead in p53-dependent or independent pathways. P53 induces the anti-inflammatory programmed cell death in cancer cells; on the other hand, IFN gamma (IFNγ) is a modulatory/pro-inflammatory
Zahra Abbasy +10 more
openaire +2 more sources
BMC Cell Biology, 2002 Background Liver fibrosis is the common sequel of chronic liver diseases. Recent studies have identified hepatic stellate cells as the primary cell type mediating hepatic fibrogenesis.
Minuk Gerald Y +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
mBio, 2019 Interferon-regulated immune defenses protect mammals from pathogenically diverse obligate intracellular bacterial pathogens of the genus Chlamydia. Interferon gamma (IFN-γ) is especially important in controlling the virulence of Chlamydia species and ...
Amanda M. Giebel +11 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source