Results 41 to 50 of about 208,098 (169)

Detecting differential usage of exons from RNA-Seq data

, 2012
RNA-Seq is a powerful tool for the study of alternative splicing and other forms of alternative isoform expression. Understanding the regulation of these processes requires comparisons between treatments, tissues or conditions.
Simon Anders, Wolfgang Huber, Alejandro Reyes   +2 more
core   +1 more source

Integrated Analysis of m6A Methylome in Cisplatin-Induced Acute Kidney Injury and Berberine Alleviation in Mouse

Frontiers in Genetics, 2020
BackgroundN6-methyladenosine (m6A) is the most abundant modification known in mRNAs. It participates in a variety of physiological and pathological processes, such as metabolism, inflammation, and apoptosis.AimsTo explore the mechanism of m6A in ...
Jianxiao Shen, Wanpeng Wang, Xinghua Shao, Jingkui Wu, Shu Li, Xiajing Che, Zhaohui Ni   +6 more
doaj   +1 more source

cyang235/smooth-seq: Smooth-seq

, 2021
A pipeline for Smooth-seq data ...
cyang235
core   +1 more source

Characterisation of bovine leukocyte Ig-like receptors

, 2012
Leukocyte Immunoglobulin-like receptors (LILR) are innate immune receptors involved in regulating both innate and adaptive immune functions. LILR show more interspecies conservation than the closely related Killer Ig-like receptors, and homologues have ...
Laing Ken, Martin Vordermeier, John Trowsdale, Singh Mahavir, Philip Butcher (173962), Allen Rachel L., Ken Laing, Laing, K, Butcher, P, Mahavir Singh, Des C Jones, Butcher, Philip, Bhuju, S, Ken Laing (173955), Vordermeier, M, Singh, Mahavir, Jones, DC, Trowsdale, John, Mahavir Singh (70735), Rachel L Allen, Hogan, Louise, Trowsdale, J, Hogan Louise, Vordermeier Martin, Hogan, L, Philip Butcher, Singh, M, Allen, RL, Des C. Jones (173949), Louise Hogan (173942), John Trowsdale (1225), Martin Vordermeier (108962), Trowsdale John, Vordermeier, Martin, Allen, Rachel L, Jones Des C., Sabin Bhuju, Laing, Ken, Bhuju Sabin, Sabin Bhuju (107606), Rachel L. Allen (173972), Jones, Des C, Bhuju, Sabin, Louise Hogan, Butcher Philip   +44 more
core   +1 more source

FLOUR-seq

, 2023
Pipeline for HIgh-throughput Single-cell ONT Full-length RNA sequencing (FLOUR-seq)
Chen Zhang (17106835)
core   +1 more source

Intra-Vκ Cluster Recombination Shapes the Ig Kappa Locus Repertoire

Cell Reports, 2019
Summary: During V(D)J recombination, RAG proteins introduce DNA double-strand breaks (DSBs) at recombination signal sequences (RSSs) that contain either 12- or 23-nt spacer regions.
Kenta Shinoda, Yaakov Maman, Andres Canela, David G. Schatz, Ferenc Livak, André Nussenzweig   +5 more
doaj   +1 more source

Remibrutinib (LOU064) inhibits neuroinflammation driven by B cells and myeloid cells in preclinical models of multiple sclerosis

Journal of Neuroinflammation, 2023
Background Bruton’s tyrosine kinase (BTK) is a key signaling node in B cell receptor (BCR) and Fc receptor (FcR) signaling. BTK inhibitors (BTKi) are an emerging oral treatment option for patients suffering from multiple sclerosis (MS).
Barbara Nuesslein-Hildesheim, Enrico Ferrero, Cindy Schmid, Catherine Huck, Paul Smith, Sarah Tisserand, Joelle Rubert, Frederic Bornancin, Denis Eichlisberger, Bruno Cenni   +9 more
doaj   +1 more source

bw files for ATAC-seq

, 2023
Through the assay for transposase-accessible chromatin sequencing (ATAC-seq) and RNA-seq analysis, we identified the regulatory network underlying leaf senescence.
Wang (17453556)
core   +1 more source

AIRR-C IG Reference Sets: curated sets of immunoglobulin heavy and light chain germline genes

Frontiers in Immunology
IntroductionAnalysis of an individual’s immunoglobulin (IG) gene repertoire requires the use of high-quality germline gene reference sets. When sets only contain alleles supported by strong evidence, AIRR sequencing (AIRR-seq) data analysis is more ...
Andrew M. Collins, Mats Ohlin, Martin Corcoran, James M. Heather, James M. Heather, Duncan Ralph, Mansun Law, Jesus Martínez-Barnetche, Jian Ye, Eve Richardson, William S. Gibson, Oscar L. Rodriguez, Ayelet Peres, Gur Yaari, Corey T. Watson, William D. Lees, William D. Lees   +16 more
doaj   +1 more source

ASAP - A Webserver for Immunoglobulin-Sequencing Analysis Pipeline

Frontiers in Immunology, 2018
Reproducible and robust data on antibody repertoires are invaluable for basic and applied immunology. Next-generation sequencing (NGS) of antibody variable regions has emerged as a powerful tool in systems immunology, providing quantitative molecular ...
Oren Avram, Anna Vaisman-Mentesh, Dror Yehezkel, Haim Ashkenazy, Tal Pupko, Yariv Wine   +5 more
doaj   +1 more source