Results 21 to 30 of about 208,098 (169)
IgD shapes the pre-immune naïve B cell compartment in humans
Frontiers in Immunology, 2023 B cell maturation and immunoglobulin (Ig) repertoire selection are governed by expression of a functional B cell receptor (BCR). Naïve B cells co-express their BCR as IgM and IgD isotype.
Johannes Dirks +6 more
doaj +1 more source
A comprehensive evaluation of alignment algorithms in the context of RNA-seq. [PDF]
, 2012 Transcriptome sequencing (RNA-Seq) overcomes limitations of previously used RNA quantification methods and provides one experimental framework for both high-throughput characterization and quantification of transcripts at the nucleotide level.
Friedel, Caroline C. +8 more
core +1 more source
, 2022 What's Changed ci: bump action versions by @jsstevenson in https://github.com/GenomicMedLab/cool-seq-tool/pull/109 refactor!: rename uta tools to cool seq tool by @korikuzma in https://github.com/GenomicMedLab/cool-seq-tool/pull/110 Staging by ...
Kuzma, Kori +2 more
core +1 more source
Cell Reports, 2017 Antibody repertoire diversity and plasticity is crucial for broad protective immunity. Repertoires change in size and diversity across multiple B cell developmental stages and in response to antigen exposure.
Victor Greiff +10 more
doaj +1 more source
Characterization of immunoglobulin loci in the gigantic genome of Ambystoma mexicanum
Frontiers in Immunology, 2023 BackgroundThe axolotl, Ambystoma mexicanum is a unique biological model for complete tissue regeneration. Is a neotenic endangered species and is highly susceptible to environmental stress, including infectious disease.
Jesús Martinez-Barnetche +11 more
doaj +1 more source
Frontiers in Immunology, 2019 Next generation sequencing (NGS) of immunoglobulin (Ig) repertoires (Rep-seq) enables examination of the adaptive immune system at an unprecedented level. Applications include studies of expressed repertoires, gene usage, somatic hypermutation levels, Ig
Néstor Vázquez Bernat +7 more
doaj +1 more source
Frontiers in Immunology, 2022 Immunoproteomics has emerged as a versatile tool for analyzing the antibody repertoire in various disease contexts. Until recently, characterization of antibody molecules in biological fluids was limited to bulk serology, which identifies clinically ...
Steven Ionov, Jiwon Lee
doaj +1 more source
Plaque reduction neutralizing antibody titers (90%) of ZIKV-IG and placebo-IG-treated animals.
, 2022 Longitudinal neutralizing antibody titers of ZIKV-IG-treated animals (red). Placebo-IG PRNT90 titers were measured at 0 and 27 dpi only (blue). Dotted vertical lines represent the time point 1 hour post-ZIKV-IG infusion for reference. Mean titers with 95%
Tulika Singh (7310102) +32 more
core +1 more source
Nbs1 ChIP-Seq Identifies Off-Target DNA Double-Strand Breaks Induced by AID in Activated Splenic B Cells. [PDF]
PLoS Genetics, 2015 Activation-induced cytidine deaminase (AID) is required for initiation of Ig class switch recombination (CSR) and somatic hypermutation (SHM) of antibody genes during immune responses.
Lyne Khair +4 more
doaj +1 more source
Results of ChIP-Seq and DNase-Seq
, 2023 Results of ChIP-Seq and DNase-Seq for Cavendish banana ...
Xiuxiu Li (13880603)
core +1 more source