Results 11 to 20 of about 44,977 (202)
Cleveland Clinic Journal of Medicine, 2023 Immunoglobulin A nephropathy (IgAN) is the most common glomerulonephritis in the world. The etiology is unknown but a dysregulated T-cell immune response to viral, bacterial, and food antigens activating mucosal plasma cells to produce polymeric IgA has been proposed. No serological test exists to diagnosis IgAN.
Jonathan J, Taliercio, Ali, Mehdi
openaire +5 more sources
Nature Reviews Disease Primers, 2016 Globally, IgA nephropathy (IgAN) is the most common primary glomerulonephritis that can progress to renal failure. The exact pathogenesis of IgAN is not well defined, but current biochemical and genetic data implicate overproduction of aberrantly glycosylated IgA1.
Schena, FP +6 more
+10 more sources
Annual Review of Medicine, 1987 IgA nephropathy is a syndrome and probably the most important glomerular disease in terms of incidence and mortality. This review documents the clinical and pathological features and concentrates on the evolving thoughts regarding pathogenesis and treatment.
A R, Clarkson +4 more
openaire +4 more sources
Clinical Journal of the American Society of Nephrology, 2017 IgA nephropathy (IgAN) is a leading cause of CKD and renal failure. Recent international collaborative efforts have led to important discoveries that have improved our understanding of some of the key steps involved in the immunopathogenesis of IgAN. Furthermore, establishment of multicenter networks has contributed to rigorous design and execution of ...
Jennifer C, Rodrigues +2 more
openaire +4 more sources
Lack of serologic evidence to link IgA nephropathy with celiac disease or immune reactivity to gluten. [PDF]
PLoS ONE, 2014 IgA nephropathy is the most common form of primary glomerulonephritis worldwide. Mucosal infections and food antigens, including wheat gluten, have been proposed as potential contributing environmental factors.
Sina Moeller +7 more
doaj +1 more source
Urinary MicroRNA Profiling in the Nephropathy of Type 1 Diabetes [PDF]
, 2013 Background: Patients with Type 1 Diabetes (T1D) are particularly vulnerable to development of Diabetic nephropathy (DN) leading to End Stage Renal Disease.
A Krupa +67 more
core +12 more sources
Serological Measurement of Poly-IgA Immune Complex Levels in IgA Nephropathy and IgA Vasculitis
Bio-Protocol, 2022 Both IgA nephropathy and IgA vasculitis, formerly known as Henoch-Schӧnlein purpura, are immune deposition diseases. IgA nephropathy is caused by the deposition of aberrantly formed poly-IgA complexes from blood circulation to the kidney glomerulus; IgA ...
Xue Zhang +6 more
doaj +1 more source
Vogt-Koyanagi-Harada Syndrome in Two Patients with Immunoglobulin A Nephropathy [PDF]
, 2007 We describe herein 2 patients who developed Vogt-Koyanagi-Harada syndrome in the course of renal biopsy-proven immunoglobulin A (IgA) nephropathy. A 61-year-old man with an 11-year history of IgA nephropathy and a 16-year history of thyroiditis, and a 56-
Masuda, Ikuya +5 more
core +1 more source
Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis [PDF]
, 2017 IgA nephropathy (IgAN) is the most prevalent among primary glomerular diseases worldwide. Although our understanding of IgAN has advanced significantly, its underlying biology and potential drug targets are still unexplored.
Cisek, Katryna +11 more
core +2 more sources
Journal of the American Society of Nephrology, 2005 14863
Barratt, J, Feehally, J
openaire +3 more sources