Results 41 to 50 of about 44,747 (232)

A Case of Henoch-Schonlein Purpura Associated with Rotavirus Infection in an Elderly Asian Male and Review of the Literature. [PDF]

open access: yes, 2017
BACKGROUND Henoch-Schönlein purpura (HSP), a small vessel vasculitis mediated by deposition of immune-complexes containing IgA in the skin, gut, and glomeruli, often presents with abdominal pain, purpuric rash in the lower extremities and buttocks, joint
Adderley   +13 more
core   +2 more sources

IgA nephropathy in a patient with ankylosing spondylitis well controlled with etanercept [PDF]

open access: yesKosin Medical Journal, 2018
Ankylosing spondylitis (AS) can involve the eye, gastrointestinal system, cardiopulmonary system, skin, kidneys, and spinal and peripheral joints. It is rarely accompanied by immunoglobulin A (IgA) nephropathy. Although IgA is involved in both AS and IgA
Do-Hyeong Lee   +3 more
doaj   +1 more source

Integration of three machine learning algorithms identifies characteristic RNA binding proteins linked with diagnosis, immunity and pyroptosis of IgA nephropathy

open access: yesFrontiers in Genetics, 2022
Objective: RNA-binding proteins (RBPs) are essential for most post-transcriptional regulatory events, which exert critical roles in nearly all aspects of cell biology.
Xueqin Zhang   +7 more
doaj   +1 more source

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

open access: yes, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim   +1 more
core   +1 more source

Serum Free Light Chains Removal by HFR Hemodiafiltration in Patients with Multiple Myeloma and Acute Kidney Injury. a Case Series [PDF]

open access: yes, 2018
Background/Aims: Multiple myeloma (MM) represents 10% of all haematologic malignancies. Renal involvement occurs in 50% of MM patients; of them, 12-20% have acute kidney injury (AKI), with 10% needing dialysis at presentation. While hemodialysis (HD) has
Antolino, Giusy   +7 more
core   +2 more sources

Aspirin alleviates the symptoms of immunoglobulin A nephropathy via suppressing platelets-mediated non-canonical NF-κB activation in B cells

open access: yesSTEMedicine, 2023
Purpose: Antiplatelet aggregation drugs, such as aspirin, can alleviate pathological renal damage in immunoglobulin A (IgA) nephropathy, although the precise mechanism is unclear.
Nomvula Johannes, Priyanka Maunga
doaj   +1 more source

Targeted-release budesonide in immunoglobulin A nephropathy; a mini-review [PDF]

open access: yesJournal of Nephropharmacology, 2023
Immunoglobulin A nephropathy is the most common kind of primary glomerulonephritis worldwide and one of the main causes of renal failure. Systemic corticosteroid therapy may protect against renal deterioration in IgA nephropathy; however, it is not often
Shiva Toumaj   +3 more
doaj   +1 more source

New developments in the genetics, pathogenesis, and therapy of IgA nephropathy [PDF]

open access: yes, 2015
Recent years have brought notable progress in the field of IgA nephropathy. Here, we highlight important new directions and latest developments, including successful discovery of several genetic susceptibility loci, formulation of the multihit ...
Appel, Gerald B.   +3 more
core   +2 more sources

Steroid therapy is effective for IgA nephropathy after liver transplantation in a pediatric patient

open access: yesClinical Case Reports, 2021
Hepatic IgA nephropathy is a complication of chronic liver disease. IgA nephropathy after liver transplantation is rare, especially in children, and carries a significant risk factor for chronic renal failure and mortality.
Hiroshi Tamura   +2 more
doaj   +1 more source

Immunoglobulin A-nephropathy: modern view of the problem and treatment options

open access: yesЛечащий Врач, 2021
The presented review discusses the mechanisms of development, the issues of diagnosis and the possibility of therapy for IgAnephropathy. IgA-nephropathy is an immunocomplex lesion of the glomeruli, characterized by the predominant deposition of ...
I. T. Murkamilov   +3 more
doaj   +1 more source

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