Results 51 to 60 of about 44,977 (202)

Molecular stratification of antiphospholipid syndrome through integrative analysis of the whole‐blood RNA transcriptome

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Antiphospholipid syndrome (APS) is a thrombo‐inflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)‐positive patients using whole‐blood transcriptomics.
Amala Ambati   +13 more
wiley   +1 more source

Association of urinary NGAL and early diagnosis and prognosis of IgA nephropathy

open access: yesZhongguo linchuang yanjiu, 2023
Objective To investigate the value of urinary neutrophil gelatinase-associated lipocalin (NGAL) in the early diagnosis of IgA nephropathy and its relationship with the cumulative survival rate of kidney in patients with IgA nephropathy.
SHI Jia-jia*, ZHU Guo-zhen
doaj   +1 more source

IgA nephropathy

open access: yesKidney International, 1995
IgAN is the most common type of glomerulonephritis worldwide, and is found more in men and distinctly less in blacks. It presents with macroscopic hematuria in about 40 to 45% of patients, with microscopic hematuria and proteinuria in about 35 to 40%, and with nephrotic syndrome or acute renal failure in the remainder.
openaire   +2 more sources

Discordant Vitamin B12 Results in an IgA Nephropathy Patient

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background Discordant Vitamin B12 results can result from immunoassay interferences, potentially leading to unnecessary diagnostic procedures and misdiagnoses if not properly recognized. Case Presentation A 76‐year‐old male with a history of IgA nephropathy, hypertension, and other comorbidities presented with unexpectedly elevated total ...
Oytun Portakal   +3 more
wiley   +1 more source

Efficacy and safety of artesunate for patients with IgA nephropathy: a study protocol for a multicenter, double-blind, randomized, placebo-controlled trial

open access: yesTrials, 2022
Background IgA nephropathy is the most common glomerular disease and is a common cause of progression to end-stage renal disease in patients with kidney diseases.
Qi Chen   +11 more
doaj   +1 more source

Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar   +11 more
wiley   +1 more source

Causal role of immune cells in IgA nephropathy: a mendelian randomization study

open access: yesRenal Failure
Background Previous observational studies have shown that immune cells play an important role in IgA nephropathy. However, the specific causal relationship between the two is inconsistent.Methods We used a two-sample mendelian randomization(MR) analysis ...
Jinlian Shu, Yating Ge, Yonggui Wu
doaj   +1 more source

Reversible acute renal failure in a patient with IgA nephropathy [PDF]

open access: yes, 1995
Reversible acute renal failure is a rare complication of IgA nephropathy. We report a patient with IgA nephropathy who developed acute renal failure after an episode of gross haematuria.
Chan, DTM, Chan, KW, Cheng, IKP, Lui, SL
core  

Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF‐κB Signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley   +1 more source

Chronic Kidney Disease – Where Next? : Predicting Outcomes And Planning Care Pathways [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Black, Corri   +2 more
core   +1 more source

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