Results 61 to 70 of about 44,747 (232)

Development of a Novel UPC (Urine Red Blood Cell Distribution, Proteinuria, and Serum Creatinine) Index to Differentiate Glomerular from Nonglomerular Hematuria

Journal of Clinical Laboratory Analysis, EarlyView.
The study developed the UPC index by integrating urine red blood cell distribution (URD), urine protein strip, and serum creatinine to enhance the diagnostic accuracy for distinguishing glomerular from nonglomerular hematuria. The UPC index demonstrated superior performance (AUC 0.857) compared to conventional parameters, showing high sensitivity and ...
Hae In Bang, Sun Min Lee, In Hee Lee, A‐Jin Lee, Chang‐Ho Jeon   +4 more
wiley   +1 more source

Chronic Kidney Disease – Where Next? : Predicting Outcomes And Planning Care Pathways [PDF]

, 2014
Peer reviewedPublisher ...
Black, Corri, Fluck, Nicholas, Marks, Angharad   +2 more
core   +1 more source

IgA Glycosylation in IgA Nephropathy [PDF]

, 1998
IgA nephropathy (IgAN) is the commonest form of glomerulonephritis in developed countries where renal biopsy is widely practiced1. IgAN is defined by the deposition of IgA in the glomerular mesangium. Most typically, patients present with episodes of visible haematuria, which often concide with respiratory or gastrointestinal infection.
A, Allen, J, Feehally
openaire   +2 more sources

Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease

Journal of Periodontology, EarlyView.
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar, Jeba Mercy Gnanasekaran, Niyant Ganesh, Cindy Zhou, Amy Plotkin, Giacomo Baima, Massimo Costalonga, Fenfen Zhou, Hanping Feng, Priyam Jani, Jean‐Pierre Raufman, Vivek Thumbigere‐Math   +11 more
wiley   +1 more source

Exploring the causal effect of complement and IgA nephropathy—a Mendelian randomization study

Renal Failure
IgA nephropathy, one of the most common primary glomerulonephritis worldwide, is still under investigation for its precise etiology. The widely accepted theory is the ‘four-hit model’ and subsequent complement and inflammatory responses.
Han Xu, Mengxiao Zou, Yichun Cheng, Shuwang Ge   +3 more
doaj   +1 more source

Half a century of IgA nephropathy: achievements, frustrations and challenges

Український Журнал Нефрології та Діалізу, 2018
IgA nephropathy is the most common glomerulonephritis worldwide. This disease has a tremendous economic impact because renal replacement therapy is expensive and hard-to-reach.
I.I. Lapchynska
doaj   +1 more source

Gut Microbes in Immunoglobulin A Nephropathy and Their Potential Therapeutic Applications

Frontiers in Medicine, 2022
Microbial ecosystem consists of a complex community of bacterial interactions and its host microenvironment (tissue, cell, metabolite). Because the interaction between gut microbiota and host involves many diseases and seriously affects human health, the
Yi Wang, Lingling Tian, Lin Sun, Wenjing Zhou, Wenqiang Zhi, Jianbo Qing, Yasin Abdi Saed, Lina Dong, Xiadong Zhang, Yafeng Li, Yafeng Li, Yafeng Li, Yafeng Li   +12 more
doaj   +1 more source

Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone

JEADV Clinical Practice, EarlyView.
ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri, Marta Dechant, Tilo Biedermann   +2 more
wiley   +1 more source

Clinical Characteristics and Treatment Patterns of Children and Adults With IgA Nephropathy or IgA Vasculitis: Findings From the CureGN Study [PDF]

, 2018
Introduction: The Cure Glomerulonephropathy Network (CureGN) is a 66-center longitudinal observational study of patients with biopsy-confirmed minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, or IgA nephropathy (IgAN)
Ambruzs, Josephine M., Appel, Gerald B., Bomback, Andrew S., Cai, Yi, Cattran, Daniel C., Chishti, Aftab S., CureGN Consortium, D’Agati, Vivette D., D’Alessandri-Silva, Cynthia J., Falk, Ronald J., Flessner, Michael, Gbadegesin, Rasheed A., Gharavi, Ali G., Gillespie, Brenda W., Gipson, Debbie S., Greenbaum, Larry A., Guay-Woodford, Lisa M., Hogan, Jonathan J., Holzman, Lawrence B., Iragorri, Sandra, Jennette, J. Charles, Julian, Bruce A., Khalid, Myda, Kiryluk, Krzysztof, Kretzler, Matthias, Lafayette, Richard A., Liapis, Helen, Lugani, Francesca, Mansfield, Sarah A., Mason, Sherene, Matar, Raed Bou, Nachman, Patrick H., Nast, Cynthia C., Nester, Carla M., Noone, Damien G., Novak, Jan, O’Shaughnessy, Michelle M., Reich, Heather N., Rheault, Michelle N., Rizk, Dana V., Robinson, Bruce M., Saha, Manish K., Sanghani, Neil S., Selewski, David T., Smoyer, William E., Sperati, C. John, Sreedharan, Rajasree, Srivastava, Tarak, Swiatecka-Urban, Agnieszka, Twombley, Katherine, Vasylyeva, Tetyana L., Weaver, Donald J., Yin, Hong, Zee, Jarcy   +53 more
core   +1 more source

Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF‐κB Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley   +1 more source