TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum
Insect Science, EarlyView.RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li +8 more
wiley +1 more source
Preclinical pharmacology, pharmacokinetics, and pharmacodynamics of veligrotug, a full antagonist antibody to the IGF-1 receptor in development for thyroid eye disease. [PDF]
MAbsKaplan R +6 more
europepmc +1 more source
Sharing the Same Playground? An Analysis of the Private Sector's Role in Tech Diplomacy
Global Policy, EarlyView.ABSTRACT This article takes the emergence of tech diplomacy as the motivation for an investigation into shifting relationships between traditional diplomatic actors and non‐state actors. The observation that ‘new diplomatic actors’ and new diplomatic venues have led to a ‘new kind of diplomacy’ dates back to at least the 1990s.
Katharina E. Höne
wiley +1 more source
Tales of Cyberspace and Artificial Intelligence: Diverging Stakeholderships?
Global Policy, EarlyView.ABSTRACT This article traces the evolution of the Internet from the 1990s to the 2020s and compares it with the development of Artificial Intelligence (AI), particularly following the public launch of ChatGPT in late 2022. It identifies both parallels and divergencies between these two overlapping technological domains, focusing on the growing ...
Johan Eriksson, Giampiero Giacomello
wiley +1 more source
Predictive Modeling of Central Precocious Puberty Using IGF-1 and IGFBP-3 Standard Deviation Scores. [PDF]
Diagnostics (Basel)Choi R, Chun G, Cho SE, Lee SG.
europepmc +1 more source
Australasian Journal of Dermatology, EarlyView.ABSTRACT Background/Objectives Post‐inflammatory hyperpigmentation (PIH) is a frequent sequela of acne in patients with skin of colour (SOC). While sunscreen is widely recommended for PIH prevention, little is known about real‐world sunscreen practices in this group. This study aimed to evaluate sunscreen use, barriers and factors influencing adherence
Xiaozhun Hang, Davin Sui Lim, Lisa Byrom
wiley +1 more source
The relationship between IGF-1 and cardiovascular diseases and the potential mediating role of TyG-related index: evidence from a cohort study. [PDF]
BMC Cardiovasc DisordChen H, Huang N, Huang Y, Chen J, Luo X.
europepmc +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To study ocular fundus morphology and its relation to growth in adolescents born moderate‐to‐late preterm (MLP) and full term. Methods This prospective and population‐based cohort study included 50 MLP adolescents (26 girls, mean age 16.5 years) and 50 full‐term controls (30 girls, mean age 16.7 years).
Alexandra Lind +6 more
wiley +1 more source
IGF-1 protects against acute pancreatitis by suppressing NF-κB activation through the β-arrestin1/STAT3 pathway. [PDF]
Mol Cell BiochemHuang X, Tao L, Liu H, Luo H, Guo Y.
europepmc +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To assess in Royal College of Surgeons (RCS) rats if the combination of two previously documented neuroprotective strategies: minocycline administration and bone marrow–derived mononuclear cells (BM‐MNCs) intravitreal transplantation, offers enhanced neuroprotection compared with each treatment alone.
Alba Videla‐Ristol +6 more
wiley +1 more source