Results 211 to 220 of about 231,978 (311)

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

VIEW, EarlyView.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li, Yulan Liu, Yuran Li, Yingjie Hua, Xinquan Jiang, Mingliang Zhou   +5 more
wiley   +1 more source

Clomiphene Citrate in Men With Hypogonadism-Do we Need to Monitor IGF-1 in All Patients? [PDF]

J Endocr Soc
Hinojosa-Amaya JM, Varlamov EV, Fleseriu M.   +2 more
europepmc   +1 more source

Plasma Proteomics Analysis Identifying IGFBP2 as a Potential Diagnostic Biomarker for Laryngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Currently, there are no blood biomarkers available for the early diagnosis of laryngeal squamous cell carcinoma (LSCC). The objective of this study was to search for potential plasma biomarkers for the diagnosis of LSCC. Methods Plasma samples were taken from patients with LSCC and healthy controls for proteomic analysis.
Shuang Teng, Ling‐Mei Qu, Jun‐Jie Liu, Yu‐Shan Li, Zi‐Qi Chen, Shuo Liu, Zhao‐Nan Xu, Meng Jin, Qiu‐Ying Li, Qin Wu, Hong‐Tian Yi, Xian‐Ji Shen, Bing‐Rui Yan, Ya‐Nan Sun   +13 more
wiley   +1 more source

Three muscle-specific DAF-16/FOXO transcriptional targets activated by reduced insulin/IGF-1 signaling. [PDF]

G3 (Bethesda)
Wu S, Gao J, Li Y, Roy C, Wang Y, Mulcahy B, Li W, Ravivarma S, Calarco J, Hung W, Zhen M.   +10 more
europepmc   +1 more source

Plasma insulin‐like growth‐factor 1 (IGF‐1) concentrations predict early life‐history traits in a wild mammal

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract The hormone insulin‐like growth factor 1 (IGF‐1) is a key player in the insulin/IGF signalling (IIS) pathway. Extensive biogerontological research demonstrates that this evolutionarily conserved nutrient‐sensing pathway plays a causal role in the regulation of growth ...
Sanjana Ravindran, Yolanda Corripio‐Miyar, Joel L. Pick, Xavier Bal, Jill G. Pilkington, Josephine M. Pemberton, Daniel H. Nussey, Hannah Froy   +7 more
wiley   +1 more source

Neuroprotective effects of hydrogen sulfide on BDNF, IGF-1, and oxidative stress in the hippocampus of high-fat diet rats. [PDF]

IBRO Neurosci Rep
Jarahi R, Moradeian H, Azami G, Ebrahimy B, Salehi I, Moridi H.   +5 more
europepmc   +1 more source

Fiscal grievance politics: wealth taxation and master‐race democracy in post‐coup Bolivia Politique des griefs fiscaux : impôt sur la fortune et démocratie de la race maîtresse en Bolivie post‐coup d’État

Journal of the Royal Anthropological Institute, EarlyView.
This article analyses a new wealth tax (the IGF) in Bolivia against the backdrop of the 2019 ousting of former president Evo Morales. In doing so, it engages calls for ‘a return to politics’ in anthropology by proposing the notion of a ‘fiscal grievance politics’ as animating elite opposition to the tax in lowland Santa Cruz department. I show that the
Charles Dolph
wiley   +1 more source

MicroRNA-Induced Regulation of the IGF-1 System in Various Types of Cancer. [PDF]

Genes (Basel)
Triantafyllou G, Kategianni M, Maridaki M, Koutsilieris M, Philippou A.   +4 more
europepmc   +1 more source

TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum

Insect Science, EarlyView.
RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li, Jie Chen, Zi‐Ye Wang, Fei‐Feng Wang, Lu‐Lu Dong, Jun Pan, Min‐Er Li, Lin Yu, Wen Sang   +8 more
wiley   +1 more source

IGF-1 from bone marrow Adipoq-lineage cells stimulates endocortical bone formation in mature female mice. [PDF]

JBMR Plus
Bertels JC, Koehnken Sawall J, Dulmovits B, Liu X, Phan A, Ji X, Song F, Thom C, Long F.   +8 more
europepmc   +1 more source