Results 181 to 190 of about 30,609,190 (316)

Endothelial IGF-1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity. [PDF]

EMBO Rep, 2021
Haywood NJ, Luk C, Bridge KI, Drozd M, Makava N, Skromna A, Maccannell A, Ozber CH, Warmke N, Wilkinson CG, Watt NT, Koch-Paszkowski J, Teh I, Boyle JH, Smart S, Schneider JE, Yuldasheva NY, Roberts LD, Beech DJ, Sukumar P, Wheatcroft SB, Cubbon RM, Kearney MT.   +22 more
europepmc   +1 more source

Sex‐Specific Proteomic Profiling Identifies Pregnancy Zone Protein as a Complement‐Linked Marker of Adverse Prognosis in Esophageal Adenocarcinoma

International Journal of Cancer, EarlyView.
ABSTRACT Esophageal adenocarcinoma (EAC) exhibits marked male predominance with male‐to‐female ratios reaching 8.5:1, yet the molecular basis underlying this sex disparity remains poorly characterized. We analyzed 92 EAC specimens using mass spectrometry–based proteomics, comprising 47 female and 45 male tumors from treatment‐naïve patients ...
Alexander Quaas, Hanna Schiemann, Su Ir Lyu, Thomas Zander, Axel Hillmer, Hans Schlößer, Christiane J. Bruns, Reinhard Büttner, Bastian Grothey   +8 more
wiley   +1 more source

IGF-1 and insulin receptors in LepRb neurons jointly regulate body growth, bone mass, reproduction, and metabolism

Mengjie Wang, Piotr J. Czernik, Beata Lecka-Czernik, Jennifer W. Hill   +3 more
openalex   +2 more sources

Cardiometabolic Health and Risk of Breast Cancer Subtypes Among US Black Women

International Journal of Cancer, EarlyView.
ABSTRACT In the United States (US), cardiometabolic conditions and aggressive breast cancers are both more common among Black women than White women. Using data from 57,453 participants in the Black Women's Health Study (BWHS), we prospectively evaluated associations of body mass index (BMI), Type 2 diabetes, hypertension, and hypercholesterolemia with
Yifei Shan, Sarah M. Rothbard, Lynn Rosenberg, Julie R. Palmer, Mollie E. Barnard   +4 more
wiley   +1 more source

IGF-1 receptor ATP-competitive inhibitors for the treatment of Ewing sarcoma: a comprehensive virtual screening analysis for a dataset of molecules showing a wide range of chemical structures

Valentina Guaitoli, Yoanna M. Álvarez Ginarte, Luís A. Montero, Ania de la Nuez Veulens, Fabrice Leclerc   +4 more
openalex   +2 more sources

Hybrid Receptor-Mediated Molecular Delineations in TNF-α and IGF-1-Induced Costimulatory Effects [PDF]

Chandra S. Boosani, Pradeep N. Subramanyam, Gopal P. Jadhav   +2 more
openalex   +1 more source

The utility of serum markers in the conservative management of placenta accreta spectrum (PAS) by leaving the placenta in situ in women with high‐grade PAS

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate the association between serum markers and successful conservative management of patients with placenta accreta spectrum (PAS). Methods This was a retrospective case–control study where patients with high‐grade PAS between 2011 and 2025 undergoing conservative leaving the placenta in situ were included.
Ammar Al Naimi, Charlotte Wiesmann, Doerthe Brueggmann, Anna Elisabeth Hentrich, Eileen Deuster, Samira Catharina Hoock, Lukas Jennewein, Frank Louwen   +7 more
wiley   +1 more source

DAF-2/insulin IGF-1 receptor regulates motility during aging by integrating opposite signaling from muscle and neuronal tissues. [PDF]

Aging Cell, 2022
Roy C, Molin L, Alcolei A, Solyga M, Bonneau B, Vachon C, Bessereau JL, Solari F.   +7 more
europepmc   +1 more source

Interplay of the IGFBP-3 polymorphism and serum levels of IGF-1/IGFBP-3 with hormone receptor subtypes in patients with breast cancer among Palestinian women

Heba Arafat, Tengku Ahmad Damitri Al-Astani Tengku Din, Noorazliyana Shafii, Rosediani Muhamad, Ihab Naser, Nahed Al Laham, Ohood Mohammed Shamallakh   +6 more
openalex   +2 more sources

MON-620 Sub-Chronic Dosing of a Non-peptide Somatostatin 2 Receptor Agonist Reduces IGF-1 and Acutely Impacts Glucose and Insulin Homeostasis in Dogs [PDF]

Ashley P. Tovar, James E. McMahon, Jessica Graves, Phil A Frankino, Stacy Markison, Stephen F. Betz, Hubert C. Chen, Matthew Peloquin   +7 more
openalex   +1 more source